Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nicholas M. Stamatos"'
Autor:
Prajakta Shinde, Alexander Kiepas, Lei Zhang, Shreya Sudhir, Konstantinos Konstantopoulos, Nicholas M. Stamatos
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112648- (2023)
Summary: Polysialic acid (polySia) is a post-translational modification of a select group of cell-surface proteins that guides cellular interactions. As the overall impact of changes in expression of this glycan on leukocytes during infection is not
Externí odkaz:
https://doaj.org/article/431ad3410e364927a50dee5c22487d89
Autor:
Chiguang Feng, Nicholas M Stamatos, Anatoliy I Dragan, Andrei Medvedev, Melissa Whitford, Lei Zhang, Chang Song, Prasad Rallabhandi, Leah Cole, Quan M Nhu, Stefanie N Vogel, Chris D Geddes, Alan S Cross
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e32359 (2012)
We previously reported that neuraminidase (NA) pretreatment of human PBMCs markedly increased their cytokine response to lipopolysaccharide (LPS). To study the mechanisms by which this occurs, we transfected HEK293T cells with plasmids encoding TLR4,
Externí odkaz:
https://doaj.org/article/d1a75ee7f6f44000aa3d9aa8b1ba3a10
Publikováno v:
The American Journal of Medicine. 134:e64-e65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d18110cff0f3425702d4add3f049ab53
https://doi.org/10.1016/j.amjmed.2020.06.028
https://doi.org/10.1016/j.amjmed.2020.06.028
Autor:
Kim G. Hankey, Alan S. Cross, Anne Jokilammi, Abderrahman El-Maarouf, Lei Zhang, Jukka Finne, Nicholas M. Stamatos, Wilbur H. Chen
Publikováno v:
Glycobiology. 24:864-879
Polysialic acid (polySia) is a unique linear homopolymer of α2,8-linked sialic acid that has been studied extensively as a posttranslational modification of neural cell adhesion molecule in the central nervous system. Only two proteins are known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884f5fc46b9f2df87ab0632763c7652e
https://doi.org/10.1093/glycob/cwu050
https://doi.org/10.1093/glycob/cwu050
Autor:
Nicholas M. Stamatos, Bruno Venerando, Alan S. Cross, Chiguang Feng, Nadia Papini, Peter J Gomatos, Ivan Carubelli, Erik J. Bonten, Lai-Xi Wang, Alessandra d'Azzo, Diantha van de Vlekkert
Publikováno v:
Journal of Leukocyte Biology. 88:1227-1239
Neu1 and Neu3 are up-regulated as monocytes differentiate into DCs; and desialylation of cell surface glycoconjugates by one or both sialidase promotes cytokine production. Removal of sialic acid from glycoconjugates on the surface of monocytes enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df009c8e1718ea94923678dff2f1253
https://doi.org/10.1189/jlb.1209776
https://doi.org/10.1189/jlb.1209776
Publikováno v:
Journal of Leukocyte Biology. 81:284-296
Sialidases influence cellular activity by removing terminal sialic acid from glycoproteins and glycolipids. Four genetically distinct sialidases (Neu1-4) have been identified in mammalian cells. In this study, we demonstrate that only lysosomal Neu1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142094f1ff06e7b9e258d6b99fbb2cc7
https://doi.org/10.1189/jlb.1105692
https://doi.org/10.1189/jlb.1105692
Autor:
Xinli Nan, Alan S. Cross, Lai-Xi Wang, Alexey V. Pshezhetsky, Nicholas M. Stamatos, Karine Landry, Feng Liang
Publikováno v:
FEBS Journal. 272:2545-2556
Sialidases are enzymes that influence cellular activity by removing terminal sialic acid from glycolipids and glycoproteins. Four genetically distinct sialidases have been identified in mammalian cells. In this study, we demonstrate that three of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9e3663cd0e4d1fae040e8a10c93639
https://doi.org/10.1111/j.1742-4658.2005.04679.x
https://doi.org/10.1111/j.1742-4658.2005.04679.x
Autor:
Douglas D. Bannerman, Jie Zhou, Alan S. Cross, Salahaldin Rifat, Simeon E. Goldblum, Serhan Sakarya, Nicholas M. Stamatos
Publikováno v:
Glycobiology. 14:481-494
The amount of sialic acid on the surface of the neutrophil (PMN) influences its ability to interact with other cells. PMN activation with various stimuli mobilizes intracellular sialidase to the plasma membrane, where it cleaves sialic acid from cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e15a15e6af900b4fdab884b7accc3e
https://doi.org/10.1093/glycob/cwh065
https://doi.org/10.1093/glycob/cwh065
Publikováno v:
Journal of Leukocyte Biology. 75:307-313
Modulation of the sialic acid content of cell-surface glycoproteins and glycolipids influences the functional capacity of cells of the immune system. The role of sialidase(s) and the consequent desialylation of cell surface glycoconjugates in the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d2628dfe4009ccdf1bdd529a2ecd6
https://doi.org/10.1189/jlb.0503241
https://doi.org/10.1189/jlb.0503241
Autor:
Frederick J. Cassels, Salahaldin Rifat, Beth Ellen Drysdale, Nicholas M. Stamatos, Alan S. Cross, Apurba K. Bhattacharjee, Ann M. Farese, Philippe A. Grange, Daniel B. Casey, Thomas K. Held, Lai-Xi Wang, Serhan Sakarya, Simeon E. Goldblum, Michael Kleinberg, Jan Powell
Publikováno v:
Journal of Biological Chemistry. 278:4112-4120
Upon activation with various noncytokine stimuli, polymorphonuclear leukocytes (PMNs) mobilize intracellular sialidase to the plasma membrane, where the sialidase releases sialic acid from the cell surface. This desialylation enhances PMN adherence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf57884f76bc9e39547ae49de2581dd
https://doi.org/10.1074/jbc.m207591200
https://doi.org/10.1074/jbc.m207591200