Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicholas M. Oyster"'
Autor:
Elisia D. Tichy, David K. Sidibe, Christopher D. Greer, Nicholas M. Oyster, Panteleimon Rompolas, Nadia A. Rosenthal, Helen M. Blau, Foteini Mourkioti
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Background Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regene
Externí odkaz:
https://doaj.org/article/27ec8e7c1d7b4772a6981532d288802e
Autor:
Maryam Sharifi‐Sanjani, Nicholas M. Oyster, Elisia D. Tichy, Kenneth C. Bedi, Ofer Harel, Kenneth B. Margulies, Foteini Mourkioti
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 9 (2017)
BackgroundTelomere defects are thought to play a role in cardiomyopathies, but the specific cell type affected by the disease in human hearts is not yet identified. The aim of this study was to systematically evaluate the cell type specificity of tel
Externí odkaz:
https://doaj.org/article/d5b5322344714474bc23a249995e50c1
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2019)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Stem cell-based bone tissue engineering shows promise for bone repair but faces some challenges, such as insufficient osteogenesis and limited architecture flexibility of the cell-delivery scaffold. Methods In this study, we first used len
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4be7cb7d470e3237160dc6fc6410677
http://link.springer.com/article/10.1186/s13287-019-1350-6
http://link.springer.com/article/10.1186/s13287-019-1350-6
Projection Stereolithographic Fabrication of BMP-2 Gene-activated Matrix for Bone Tissue Engineering
Autor:
Rocky S. Tuan, Madalyn R. Fritch, Robert B. Kang, Bing Wang, Ying Tang, Nicholas M. Oyster, Hang Lin, Thomas P. Lozito
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Currently, sustained in vivo delivery of active bone morphogenetic protein-2 (BMP-2) protein to responsive target cells, such as bone marrow-derived mesenchymal stem cells (BMSCs), remains challenging. Ex vivo gene transfer method, while efficient, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1908cb1e4560743301e6e8effd7bc091
http://link.springer.com/article/10.1038/s41598-017-11051-0
http://link.springer.com/article/10.1038/s41598-017-11051-0
Autor:
Ofer Harel, Foteini Mourkioti, Maryam Sharifi-Sanjani, Elisia D. Tichy, Kenneth B. Margulies, Kenneth C. Bedi, Nicholas M. Oyster
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Telomere defects are thought to play a role in cardiomyopathies, but the specific cell type affected by the disease in human hearts is not yet identified. The aim of this study was to systematically evaluate the cell type specificity of te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac59bae2fd09c7e9848540101f6fc71
http://europepmc.org/articles/PMC5634248
http://europepmc.org/articles/PMC5634248
Autor:
Ying Tang, Johnny Huard, Jonathan D. Proto, Bing Wang, Aiping Lu, Jihee Sohn, Xiaodong Mu, Nicholas M. Oyster, Minakshi Poddar
Publikováno v:
Human Molecular Genetics. 23:4786-4800
Duchenne muscular dystrophy (DMD) patients lack dystrophin from birth; however, muscle weakness becomes apparent only at 3–5 years of age, which happens to coincide with the depletion of the muscle progenitor cell (MPC) pools. Indeed, MPCs isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05b6c316296afc916a2400450653ee9
https://doi.org/10.1093/hmg/ddu194
https://doi.org/10.1093/hmg/ddu194
Autor:
Huamin Wang, Núria M. Pastor-Soler, Robert S. Edinger, Nicholas M. Oyster, John P. Johnson, Jochen Buck, Kenneth R. Hallows, Michael B. Butterworth, Lonny R. Levin, Hui Li
Publikováno v:
Journal of Biological Chemistry. 284:5774-5783
Alkalosis impairs the natriuretic response to diuretics, but the underlying mechanisms are unclear. The soluble adenylyl cyclase (sAC) is a chemosensor that mediates bicarbonate-dependent elevation of cAMP in intracellular microdomains. We hypothesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0740b4d08dd47a6364c00e94ef22af
https://doi.org/10.1074/jbc.m805501200
https://doi.org/10.1074/jbc.m805501200
Autor:
Zhirong Huang, Marjolein A. Wijngaarden, Xiaoyu Xia, Nicholas M. Oyster, Jeffrey K. Lee, Kenneth R. Hallows, Alma L. Burlingame, Hui Li, Robert J. Chalkley, Sindhu Chandran, David A. Pearce, Vivek Bhalla
The E3 ubiquitin ligase Nedd4-2 regulates several ion transport proteins, including the epithelial Na(+) channel (ENaC). Nedd4-2 decreases apical membrane expression and activity of ENaC. Although it is subject to tight hormonal control, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a92d57cb56cd8c7024d07686bdf15b
https://europepmc.org/articles/PMC2898378/
https://europepmc.org/articles/PMC2898378/
Autor:
Zhirong Huang, Xiaoyu Xia, Marjolein A. Wijngaarden, Vivek Bhalla, David A. Pearce, Hui Li, Ken Hallows, Nicholas M. Oyster, Alma L. Burlingame, Jeffrey E. Lee, Robert J. Chalkley
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87618b24d1056f33a6863f51e3eff4f9
https://doi.org/10.1096/fasebj.24.1_supplement.611.18
https://doi.org/10.1096/fasebj.24.1_supplement.611.18
Autor:
Amy Magill, Kenneth R. Hallows, Catherine J. Baty, Jay K. Kolls, Nicholas M. Oyster, Adam Fitch, J Darwin King, Michael M. Myerburg, Joseph M. Pilewski, Simon C. Watkins
Publikováno v:
American journal of respiratory cell and molecular biology. 42(6)
The metabolic sensor AMP-activated kinase (AMPK) inhibits both the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) Cl(-) channel and epithelial Na(+) channel (ENaC), and may inhibit secretion of proinflammatory cytokines in epithelia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ac6d97468f707fe647271d1db8b766
https://pubmed.ncbi.nlm.nih.gov/19617399
https://pubmed.ncbi.nlm.nih.gov/19617399