Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nicholas M. Girardi"'
Autor:
Wai Cheung Chan, Xiaoxi Liu, Robert S. Magin, Nicholas M. Girardi, Scott B. Ficarro, Wanyi Hu, Maria I. Tarazona Guzman, Cara A. Starnbach, Alejandra Felix, Guillaume Adelmant, Anthony C. Varca, Bin Hu, Ariana S. Bratt, Ethan DaSilva, Nathan J. Schauer, Isabella Jaen Maisonet, Emma K. Dolen, Anthony X. Ayala, Jarrod A. Marto, Sara J. Buhrlage
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Deubiquitinases (DUBs) are key signaling enzymes, many of which lack selective inhibitors. Chan et al. pair a DUB-focused covalent library to mass spectrometry activity-based protein profiling, leading to selective hits against 23 endogenous DUBs and
Externí odkaz:
https://doaj.org/article/d6b807ef0bbf47468c2c964d3363d37f
Autor:
Anne E. Turco, Steven R. Oakes, Kimberly P. Keil Stietz, Cheryl L. Dunham, Diya B. Joseph, Thrishna S. Chathurvedula, Nicholas M. Girardi, Andrew J. Schneider, Joseph Gawdzik, Celeste M. Sheftel, Peiqing Wang, Zunyi Wang, Dale E. Bjorling, William A. Ricke, Weiping Tang, Laura L. Hernandez, Janet R. Keast, Adrian D. Bonev, Matthew D. Grimes, Douglas W. Strand, Nathan R. Tykocki, Robyn L. Tanguay, Richard E. Peterson, Chad M. Vezina
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fifth or sixth decade and progressively worsen over the remainder of life. Here, we identify a surprising origin of this dis
Externí odkaz:
https://doaj.org/article/4952606b90dc471c92b6828b628113c4
Autor:
Nicholas M Girardi, Frank M. Raushel, Hazel M. Holden, Thomas K. Anderson, James B. Thoden, Zane W. Taylor, Jamison P. Huddleston
Publikováno v:
Biochemistry. 60:1552-1563
Campylobacter jejuni is the leading cause of food poisoning in the United States and Europe. The exterior cell surface of C. jejuni is coated with a capsular polysaccharide (CPS) that is essential for the maintenance and integrity of the bacterial ce
Publikováno v:
Protein Sci
Tens of thousands of bacterial genome sequences are now known due to the development of rapid and inexpensive sequencing technologies. An important key in utilizing these vast amounts of data in a biologically meaningful way is to infer the function
Autor:
Chad M. Vezina, Richard B. Halberg, Steven R Oakes, Brett Mueller, Paul C. Marker, Hannah Ruetten, Christopher J Unterberger, Anne E. Turco, Nicholas M Girardi, Steven M. Swanson, Enrique J Avila, Kyle A Wegner
Publikováno v:
J Pathol
We genetically engineered expression of an activated form of P110 alpha, the catalytic subunit of PI3K, in mouse prostate epithelium to create a mouse model of direct PI3K activation (Pbsn-cre4Prb;PI3KGOF/+ ). We hypothesized that direct activation w
Autor:
Nathan R. Tykocki, Cheryl L. Dunham, Nicholas M Girardi, Celeste M Sheftel, Janet R. Keast, Diya B. Joseph, Dale E. Bjorling, Laura L. Hernandez, Anne E. Turco, Chad M. Vezina, Matthew D Grimes, Weiping Tang, Thrishna S Chathurvedula, Douglas W. Strand, Peiqing Wang, Kimberly P. Keil Stietz, Steven R Oakes, William A. Ricke, Richard E. Peterson, Adrian D. Bonev, Robyn L Tanguay, Joseph Gawdzik, Andrew J. Schneider, Zunyi Wang
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 7 (2021)
Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fifth or sixth decade and progressively worsen over the remainder of life. Here, we identify a surprising origin of this dis
Autor:
Jamison P, Huddleston, Thomas K, Anderson, Nicholas M, Girardi, James B, Thoden, Zane, Taylor, Hazel M, Holden, Frank M, Raushel
Publikováno v:
Biochemistry
Campylobacter jejuni is the leading cause of food poisoning in the United States and Europe. The exterior cell surface of C. jejuni is coated with a capsular polysaccharide (CPS) that is essential for the maintenance and integrity of the bacterial ce
Autor:
Kyle A, Wegner, Hannah, Ruetten, Nicholas M, Girardi, Chelsea A, O'Driscoll, Jaskiran K, Sandhu, Anne E, Turco, Lisa L, Abler, Peiqing, Wang, Zunyi, Wang, Dale E, Bjorling, Rita, Malinowski, Richard E, Peterson, Douglas W, Strand, Paul C, Marker, Chad M, Vezina
Publikováno v:
Am J Clin Exp Urol
Urinary voiding dysfunction in aging men can cause bothersome symptoms and irreparable tissue damage. Underlying mechanisms are not fully known. We previously demonstrated that subcutaneous, slow-release testosterone and estradiol implants (T+E2) dri
Autor:
Hannah Ruetten, Marlyse Wehber, Michael W. Wood, Michael F. Romero, Nelson T. Peterson, Chad M. Vezina, Nicholas M Girardi, Clara Cole, Dale E. Bjorling, Sara A. Colopy, Kyle A Wegner, Brandon R. Scharpf
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0232564 (2020)
PLoS ONE
PLoS ONE
BackgroundThe identity and spatial distribution of prostatic cell types has been determined in humans but not in dogs, even though aging- and prostate-related voiding disorders are common in both species and mechanistic factors, such as prostatic col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2028341f4e2e4d178db2dd5478615c10