Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Nicholas M, Bernthal"'
Autor:
Alexandra M. Stein, Ambika E. Paulson, Joseph K. Kendal, Nicholas M. Bernthal, Lauren E. Wessel
Publikováno v:
Cancer Treatment and Research Communications, Vol 37, Iss , Pp 100773- (2023)
Background and Objectives: As there is an increasing reliance on the internet for medical information, patients diagnosed with rare diseases have turned to online community forums to share information about their diagnoses. These forums help patients
Externí odkaz:
https://doaj.org/article/58dd920490e947c18de4a55c29d2a2e0
Autor:
Zachary D. C. Burke, Christopher M. Hart, Benjamin V. Kelley, Zeinab Mamouei, Gideon W. Blumstein, Christopher Hamad, Kellyn Hori, Nicolas Cevallos, Christina Villalpando, Nicole Truong, Amr Turkmani, Micah Ralston, Aaron Kavanaugh, Edgar Tenorio, Lawrence M. Kauvar, Alan Li, Nathanael Prunet, Alexandra I. Stavrakis, Nicholas M. Bernthal
Publikováno v:
Antibiotics, Vol 12, Iss 10, p 1490 (2023)
Bacterial biofilms on orthopedic implants are resistant to the host immune response and to traditional systemic antibiotics. Novel therapies are needed to improve patient outcomes. TRL1068 is a human monoclonal antibody (mAb) against a biofilm anchor
Externí odkaz:
https://doaj.org/article/64cfd71921e94a6890bf163a384a5fc1
Autor:
Weixian Xi, Vishal Hegde, Stephen D. Zoller, Howard Y. Park, Christopher M. Hart, Takeru Kondo, Christopher D. Hamad, Yan Hu, Amanda H. Loftin, Daniel O. Johansen, Zachary Burke, Samuel Clarkson, Chad Ishmael, Kellyn Hori, Zeinab Mamouei, Hiroko Okawa, Ichiro Nishimura, Nicholas M. Bernthal, Tatiana Segura
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Implant infection is the most common mode of joint replacement failure with serious complications. Here, the authors report on the in vivo application of a prophylactic coating technology that can incorporate a range of antibiotics and be applied in
Externí odkaz:
https://doaj.org/article/76aa4dbb4edd442f94aaa3e0f4b4b488
Autor:
Nicholas M. Bernthal, Geert Spierenburg, John H. Healey, Emanuela Palmerini, Sebastian Bauer, TOPP Study Group, Hans Gelderblom, Eric L. Staals, Julio Lopez-Bastida, Eva-Maria Fronk, Xin Ye, Petra Laeis, Michiel A. J. van de Sande
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-13 (2021)
Abstract Background Tenosynovial giant cell tumor (TGCT) is a rare, locally aggressive neoplasm arising from the synovium of joints, bursae, and tendon sheaths affecting small and large joints. It represents a wide spectrum ranging from minimally sym
Externí odkaz:
https://doaj.org/article/1ce67f14ec8a4c31aac50afe682d5be0
Autor:
Howard Y. Park, Stephen D. Zoller, Vishal Hegde, William Sheppard, Zachary Burke, Gideon Blumstein, Christopher Hamad, Marina Sprague, John Hoang, Ryan Smith, Francisco Romero Pastrana, Julie Czupryna, Lloyd S. Miller, Marina López-Álvarez, Mafalda Bispo, Marleen van Oosten, Jan Maarten van Dijl, Kevin P. Francis, Nicholas M. Bernthal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Implant-associated infections are challenging to diagnose and treat. Fluorescent probes have been heralded as a technologic advancement that can improve our ability to non-invasively identify infecting organisms, as well as guide the inexact
Externí odkaz:
https://doaj.org/article/86227a18cd1245e9a49adb1de27d0f16
Autor:
Geert Spierenburg, Floortje G. M. Verspoor, Jay S. Wunder, Anthony M. Griffin, Peter C. Ferguson, Matthew T. Houdek, David M. King, Richard Boyle, Robert Lor Randall, Steven W. Thorpe, Jacob I. Priester, Erik J. Geiger, Lizz van der Heijden, Nicholas M. Bernthal, Bart H. W. B. Schreuder, Hans Gelderblom, Michiel A. J. van de Sande
Publikováno v:
Cancers, Vol 15, Iss 3, p 941 (2023)
Diffuse-type tenosynovial giant cell tumors’ (D-TGCTs) intra- and extra-articular expansion about the knee often necessitates an anterior and posterior surgical approach to facilitate an extensive synovectomy. There is no consensus on whether two-s
Externí odkaz:
https://doaj.org/article/25996fe3534945848be3f67ae3c19dee
Autor:
Stephen D. Zoller, Vishal Hegde, Zachary D. C. Burke, Howard Y. Park, Chad R. Ishmael, Gideon W. Blumstein, William Sheppard, Christopher Hamad, Amanda H. Loftin, Daniel O. Johansen, Ryan A. Smith, Marina M. Sprague, Kellyn R. Hori, Samuel J. Clarkson, Rachel Borthwell, Scott I. Simon, Jeff F. Miller, Scott D. Nelson, Nicholas M. Bernthal
Publikováno v:
Bone Research, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract Extremity reconstruction surgery is increasingly performed rather than amputation for patients with large-segment pathologic bone loss. Debate persists as to the optimal void filler for this “limb salvage” surgery, whether metal or allog
Externí odkaz:
https://doaj.org/article/95438cbe8f854ef4bf22ac72442d7b17
Publikováno v:
Case Reports in Orthopedics, Vol 2022 (2022)
Tenosynovial giant cell tumor (TGCT) is a rare neoplasm of the joint synovium that has a wide clinical spectrum including pain and stiffness in the affected joint, joint swelling, periarticular erosions, and cartilage loss, which can severely impact
Externí odkaz:
https://doaj.org/article/3b260c9fdcbe4677a6abceb48ed446a9
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 4, Iss 1, Pp 1-14 (2020)
Abstract Purpose The purpose of this study was to evaluate the psychometric properties of the PROMIS-Physical Function (PF) and Worst Stiffness Numeric Rating Scale (NRS) among patients with tenosynovial giant cell tumors (TGCT). Methods Measurement
Externí odkaz:
https://doaj.org/article/8777fe06495b493a8b8514ec59f3df06
Autor:
Francisco Romero Pastrana, John M. Thompson, Marjolein Heuker, Hedzer Hoekstra, Carly A. Dillen, Roger V. Ortines, Alyssa G. Ashbaugh, Julie E. Pickett, Matthijs D. Linssen, Nicholas M. Bernthal, Kevin P. Francis, Girbe Buist, Marleen van Oosten, Gooitzen M. van Dam, Daniel L. J. Thorek, Lloyd S. Miller, Jan Maarten van Dijl
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 262-272 (2018)
Staphylococcus aureus infections are a major threat in healthcare, requiring adequate early-stage diagnosis and treatment. This calls for novel diagnostic tools that allow noninvasive in vivo detection of staphylococci. Here we performed a preclinica
Externí odkaz:
https://doaj.org/article/b3948013660441b29da4311a15413d71