Zobrazeno 1 - 10
of 419
pro vyhledávání: '"Nicholas M, Anstey"'
Autor:
Angelica F Tan, Sitti Saimah Binti Sakam, Kim Piera, Giri S Rajahram, Timothy William, Bridget E Barber, Nicholas M Anstey, Matthew J Grigg, Steven Kho
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012424 (2024)
The risk of severe malaria from the zoonotic parasite Plasmodium knowlesi approximates that from P. falciparum. In severe falciparum malaria, neutrophil activation contributes to inflammatory pathogenesis, including acute lung injury (ALI). The role
Externí odkaz:
https://doaj.org/article/6ba15fe81694409a834abc0b8f340f3c
Autor:
Stephen D. Woolley, Matthew J. Grigg, Louise Marquart, Jeremy S.E. Gower, Kim Piera, Arya Sheela Nair, Fiona M. Amante, Giri S. Rajahram, Timothy William, David M. Frazer, Stephan Chalon, James S. McCarthy, Nicholas M. Anstey, Bridget E. Barber
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105189- (2024)
Summary: Background: The interaction between iron status and malaria is incompletely understood. We evaluated longitudinal changes in iron homeostasis in volunteers enrolled in malaria volunteer infection studies (VIS) and in Malaysian patients with
Externí odkaz:
https://doaj.org/article/cacdf27f70df4dd7b2ca25c9e1760fa9
Autor:
Pengxing Cao, Steven Kho, Matthew J. Grigg, Bridget E. Barber, Kim A. Piera, Timothy William, Jeanne R. Poespoprodjo, Ihn Kyung Jang, Julie A. Simpson, James M. McCaw, Nicholas M. Anstey, James S. McCarthy, Sumudu Britton
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Plasmodium vivax lactate dehydrogenase (PvLDH) is an essential enzyme in the glycolytic pathway of P. vivax. It is widely used as a diagnostic biomarker and a measure of total-body parasite biomass in vivax malaria. However, the dynamics of
Externí odkaz:
https://doaj.org/article/d48ba3507e1249c79abee4305c434258
Autor:
Nicholas L. Dooley, Tinashe G. Chabikwa, Zuleima Pava, Jessica R. Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S. F. Soon, Arya SheelaNair, Kim A. Piera, Timothy William, Bridget E. Barber, Matthew J. Grigg, Christian R. Engwerda, J. Alejandro Lopez, Nicholas M. Anstey, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the development of effective anti-parasitic immunity. Understanding malaria induced tolero
Externí odkaz:
https://doaj.org/article/d4f0ae647bca412fa846c8d4ab492791
Autor:
Ruarai J Tobin, Lucinda E Harrison, Meg K Tully, Inke N D Lubis, Rintis Noviyanti, Nicholas M Anstey, Giri S Rajahram, Matthew J Grigg, Jennifer A Flegg, David J Price, Freya M Shearer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011570 (2024)
BackgroundPlasmodium knowlesi is a zoonotic parasite that causes malaria in humans. The pathogen has a natural host reservoir in certain macaque species and is transmitted to humans via mosquitoes of the Anopheles Leucosphyrus Group. The risk of huma
Externí odkaz:
https://doaj.org/article/47b12f130f1b4c7e916f555d101f8e30
Autor:
Angelica F. Tan, Priyaleela Thota, Sitti Saimah Binti Sakam, Yao Long Lew, Giri S. Rajahram, Timothy William, Bridget E. Barber, Steven Kho, Nicholas M. Anstey, David Bell, Matthew J. Grigg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Plasmodium knowlesi is the major cause of zoonotic malaria in Southeast Asia. Rapid and accurate diagnosis enables effective clinical management. A novel malaria diagnostic tool, Gazelle (Hemex Health, USA) detects haemozoin, a by-product of
Externí odkaz:
https://doaj.org/article/51cabcc3b230470fb930eceb70eadb59
Autor:
Jeyamalar T. Thurai Rathnam, Matthew J. Grigg, Saber Dini, Timothy William, Sitti Saimah Sakam, Daniel J. Cooper, Giri S. Rajahram, Bridget E. Barber, Nicholas M. Anstey, Ali Haghiri, Megha Rajasekhar, Julie A. Simpson
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background The incidence of zoonotic Plasmodium knowlesi infections in humans is rising in Southeast Asia, leading to clinical studies to monitor the efficacy of anti-malarial treatments for knowlesi malaria. One of the key outcomes of anti-
Externí odkaz:
https://doaj.org/article/9264b50a5c56427db4cdcce28b8e8fa0
Autor:
Hidayat Trimarsanto, Roberto Amato, Richard D. Pearson, Edwin Sutanto, Rintis Noviyanti, Leily Trianty, Jutta Marfurt, Zuleima Pava, Diego F. Echeverry, Tatiana M. Lopera-Mesa, Lidia M. Montenegro, Alberto Tobón-Castaño, Matthew J. Grigg, Bridget Barber, Timothy William, Nicholas M. Anstey, Sisay Getachew, Beyene Petros, Abraham Aseffa, Ashenafi Assefa, Awab G. Rahim, Nguyen H. Chau, Tran T. Hien, Mohammad S. Alam, Wasif A. Khan, Benedikt Ley, Kamala Thriemer, Sonam Wangchuck, Yaghoob Hamedi, Ishag Adam, Yaobao Liu, Qi Gao, Kanlaya Sriprawat, Marcelo U. Ferreira, Moses Laman, Alyssa Barry, Ivo Mueller, Marcus V. G. Lacerda, Alejandro Llanos-Cuentas, Srivicha Krudsood, Chanthap Lon, Rezika Mohammed, Daniel Yilma, Dhelio B. Pereira, Fe E. J. Espino, Cindy S. Chu, Iván D. Vélez, Chayadol Namaik-larp, Maria F. Villegas, Justin A. Green, Gavin Koh, Julian C. Rayner, Eleanor Drury, Sónia Gonçalves, Victoria Simpson, Olivo Miotto, Alistair Miles, Nicholas J. White, Francois Nosten, Dominic P. Kwiatkowski, Ric N. Price, Sarah Auburn
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An online, amendable classifier for detecting malaria parasite country of origin from genomic data is developed using a machine learning approach.
Externí odkaz:
https://doaj.org/article/595d6999c2294de5a765b7b051ac5f17
Autor:
Leo Leonardo, Enny Kenangalem, Jeanne R. Poespoprodjo, Rintis Noviyanti, Ric N. Price, Nicholas M. Anstey, Gabriela Minigo, Steven Kho
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Circulating myeloid-derived-suppressor-cells (MDSC) with immunosuppressive function are increased in human experimental Plasmodium falciparum infection, but have not been studied in clinical malaria. Methods Using flow-cytometry,
Externí odkaz:
https://doaj.org/article/150c6f3bd9a849968fa8a21f34b3d52a
Autor:
Steven Kho, Nicholas M. Anstey, Bridget E. Barber, Kim Piera, Timothy William, Enny Kenangalem, James S. McCarthy, Ihn Kyung Jang, Gonzalo J. Domingo, Sumudu Britton, Matthew J. Grigg
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Commercial point-of-care tests remain insufficient for accurately detecting and differentiating low-level malaria infections in regions co-endemic with multiple non-falciparum species, including zoonotic Plasmodium knowlesi (Pk). A 5-plex ch
Externí odkaz:
https://doaj.org/article/f431d93e67034c118708832962c78c62