Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicholas L. Bray"'
Autor:
Nicholas L. Bray, Katelynn R. Kazane, Stephen N. Floor, Jacob E. Corn, Christopher D. Richardson, Sharon J. Feng, Axel J. Schäfer, Elena Zelin
Publikováno v:
Nature genetics. 50(8)
CRISPR–Cas genome editing creates targeted DNA double-strand breaks (DSBs) that are processed by cellular repair pathways, including the incorporation of exogenous DNA via single-strand template repair (SSTR). To determine the genetic basis of SSTR
Autor:
Axel J. Schaefer, Stephen N. Floor, Christopher D. Richardson, Jacob E. Corn, Nicholas L. Bray, Sharon J. Feng, Katelynn R. Kazane
CRISPR-Cas9 genome editing creates targeted double strand breaks (DSBs) in eukaryotic cells that are processed by cellular DNA repair pathways. Co-administration of single stranded oligonucleotide donor DNA (ssODN) during editing can result in high-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eba775a98084c7f4d9e3b9519f4a0a9
https://doi.org/10.1101/136028
https://doi.org/10.1101/136028
Publikováno v:
Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics
We describe pair hidden Markov models, with an emphasis on their relationship to evolutionary models and hidden Markov models. We then explain the statistical interpretation of alignment with pair hidden Markov models, and highlight connections to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cb85a8ef715fe70a89def3254baa42e
https://doi.org/10.1002/047001153x.g402215
https://doi.org/10.1002/047001153x.g402215
In this paper we describe a new global alignment method called AVID. The method is designed to be fast, memory efficient, and practical for sequence alignments of large genomic regions up to megabases long. We present numerous applications of the met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9247d0077f996ea7653bcef4aef3c92
https://resolver.caltech.edu/CaltechAUTHORS:20170308-155631683
https://resolver.caltech.edu/CaltechAUTHORS:20170308-155631683