Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicholas L Arp"'
Publikováno v:
eLife, Vol 11 (2022)
Chromosomal instability (CIN)—persistent chromosome gain or loss through abnormal mitotic segregation—is a hallmark of cancer that drives aneuploidy. Intrinsic chromosome mis-segregation rate, a measure of CIN, can inform prognosis and is a promi
Externí odkaz:
https://doaj.org/article/7f548a7a7f9c4dcaa81c622dfb9ba2ff
Autor:
Zafer Gurel, Michael S. Luy, Qianyun Luo, Nicholas L. Arp, Amy K. Erbe, Aparna H. Kesarwala, Jing Fan, Randall J. Kimple
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionLactate is a pivotal molecule with diverse functions in the metabolic reprogramming of cancer cells. Beyond its role in metabolism, lactate exerts a modulatory effect within the tumor microenvironment; it is utilized by stromal cells and
Externí odkaz:
https://doaj.org/article/e11c06729ad144b8b224cd5c1aa245f1
Autor:
Gretchen L. Seim, Steven V. John, Nicholas L. Arp, Zixiang Fang, David J. Pagliarini, Jing Fan
Publikováno v:
Nature Chemical Biology. 19:265-274
Pyruvate dehydrogenase complex (PDHC) and oxoglutarate dehydrogenase complex (OGDC), which belong to the mitochondrial α-ketoacid dehydrogenase family, play crucial roles in cellular metabolism. These multi-subunit enzyme complexes use lipoic arms c
Autor:
Katrina L. Ruedinger, Nicholas L Arp, Anqi Gao, Margot Miranda-Katz, Nasia Safdar, Austin K. Feeney, Ashley E. Kates, Emma J Graham Linck, Tung H Nguyen, Jonathan H Schrope
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
Public health agencies have recommended that the public wear face coverings as a major non-pharmaceutical intervention to mitigate COVID-19 transmission. However, there is concern whether or not the public has adopted this recommendation. An observat