Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicholas Knoblauch"'
Autor:
Siming Zhao, Jun Liu, Pranav Nanga, Yuwen Liu, A. Ercument Cicek, Nicholas Knoblauch, Chuan He, Matthew Stephens, Xin He
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Finding driver genes sheds lights on the biological mechanisms propelling the development of a tumour, and can suggest therapeutic strategies. Here, the authors develop driverMAPS, a model-based approach to identify driver genes, and apply it to TCGA
Externí odkaz:
https://doaj.org/article/e2cfc4a4bb3344c3b518ce9ae9dea3be
Autor:
Yuwen Liu, Yanyu Liang, A. Ercument Cicek, Zhongshan Li, Jinchen Li, Rebecca Muhle, Martina Krenzer, Yue Mei, Yan Wang, Nicholas Knoblauch, Jean Morrison, Siming Zhao, Yi Jiang, Evan Geller, Iuliana Ionita-Laza, Jinyu Wu, Kun Xia, James Noonan, Zhong Sheng Sun, Xin He
Analysis of de novo mutations (DNMs) from sequencing data of nuclear families has identified risk genes for many complex diseases, including multiple neurodevelopmental and psychiatric disorders. Most of these efforts have focused on mutations in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccef201a4a1661e77b6da2183d579a83
https://doi.org/10.1101/077578
https://doi.org/10.1101/077578