Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Nicholas K. Akers"'
Autor:
Travers Ching, Megan E. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter, Jeffrey M. Tracy, Michelle S. Steen, Ryan P. Brown, Srivatsa Venkatasubbarao, Nicholas K. Akers, Marissa Vignali, Martin E. Moorhead, Drew Watson, Ryan O. Emerson, Tobias P. Mann, B. Melina Cimler, Pamela L. Swatkowski, Ilan R. Kirsch, Charles Sang, Harlan S. Robins, Bryan Howie, Anna Sherwood
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The clonoSEQ® Assay (Adaptive Biotechnologies Corporation, Seattle, USA) identifies and tracks unique disease-associated immunoglobulin (Ig) sequences by next-generation sequencing of IgH, IgK, and IgL rearrangements and IgH-BCL1
Externí odkaz:
https://doaj.org/article/f4765b6429fd4f42acca9201ac81c886
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Akers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-16 (2019)
Abstract Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511
Externí odkaz:
https://doaj.org/article/a76b99477ddb49caaac1147906552dfc
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Ayers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-1 (2019)
Externí odkaz:
https://doaj.org/article/4821428476ee4beaa78f0a9545cce053
Autor:
Jordi Abril-Fornaguera, Laura Torrens, Carmen Andreu-Oller, Juan Carrillo-Reixach, Alex Rialdi, Ugne Balaseviciute, Roser Pinyol, Carla Montironi, Philipp K. Haber, Álvaro Del Río-Álvarez, Montserrat Domingo-Sàbat, Laura Royo, Nicholas K. Akers, Catherine E. Willoughby, Judit Peix, Miguel Torres-Martin, Marc Puigvehi, Stefano Cairo, Margaret Childs, Rudolf Maibach, Rita Alaggio, Piotr Czauderna, Bruce Morland, Bojan Losic, Vincenzo Mazzaferro, Ernesto Guccione, Daniela Sia, Carolina Armengol, Josep M. Llovet
Publikováno v:
Molecular Cancer Therapeutics. 22:485-498
Management of hepatoblastoma (HB), the most frequent pediatric liver cancer, is based on surgical resection and perioperative chemotherapy regimens. In this study, we aimed to identify actionable targets in HB and assess the efficacy of molecular the
Autor:
Josep M. Llovet, Carolina Armengol, Daniela Sia, Ernesto Guccione, Vincenzo Mazzaferro, Bojan Losic, Bruce Morland, Piotr Czauderna, Rita Alaggio, Rudolf Maibach, Margaret Childs, Stefano Cairo, Marc Puigvehi, Miguel Torres-Martin, Judit Peix, Catherine E. Willoughby, Nicholas K. Akers, Laura Royo, Montserrat Domingo-Sàbat, Álvaro Del Río-Álvarez, Philipp K. Haber, Carla Montironi, Roser Pinyol, Ugne Balaseviciute, Alex Rialdi, Juan Carrillo-Reixach, Carmen Andreu-Oller, Laura Torrens, Jordi Abril-Fornaguera
Management of hepatoblastoma (HB), the most frequent pediatric liver cancer, is based on surgical resection and perioperative chemotherapy regimens. In this study, we aimed to identify actionable targets in HB and assess the efficacy of molecular the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390a621810712aa475236362b5db108a
https://doi.org/10.1158/1535-7163.c.6534814.v2
https://doi.org/10.1158/1535-7163.c.6534814.v2
Autor:
Josep M. Llovet, Carolina Armengol, Daniela Sia, Ernesto Guccione, Vincenzo Mazzaferro, Bojan Losic, Bruce Morland, Piotr Czauderna, Rita Alaggio, Rudolf Maibach, Margaret Childs, Stefano Cairo, Marc Puigvehi, Miguel Torres-Martin, Judit Peix, Catherine E. Willoughby, Nicholas K. Akers, Laura Royo, Montserrat Domingo-Sàbat, Álvaro Del Río-Álvarez, Philipp K. Haber, Carla Montironi, Roser Pinyol, Ugne Balaseviciute, Alex Rialdi, Juan Carrillo-Reixach, Carmen Andreu-Oller, Laura Torrens, Jordi Abril-Fornaguera
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567fb3a489dd0bab0c7470eb009aa094
https://doi.org/10.1158/1535-7163.22552095.v1
https://doi.org/10.1158/1535-7163.22552095.v1
Autor:
Miao Jiang, Nicholas K. Akers, Darcy B. Gill, Benjamin Eckhert, Emily Svejnoha, Harlan Robins
ImportanceDespite widespread use of clinical diagnostic tests to assess prior exposure to SARS-CoV-2, limited evidence exists regarding how test results affect patient behaviors and decision-making.ObjectiveTo understand the rationale behind ordering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fabc544faa288426f2c78549160c4f7
https://doi.org/10.1101/2022.07.01.22277108
https://doi.org/10.1101/2022.07.01.22277108
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Recently proposed tumor fitness measures, based on profiling neoepitopes for reactive viral epitope similarity, have led to improved prediction models of response to immune checkpoint inhibitors in melanoma and small-cell lung cancer. Here we test if
Autor:
Cristina Beléndez, Viera Bajčiová, Nicholas K. Akers, Aroa Soriano, David Piñeyro, Manuel López Santamaría, Michael A. Grotzer, Carolina Armengol, José Antonio Salinas, Lara Nonell, Mar Mallo, Jordi Abril-Fornaguera, Bruce Morland, Roland Kappler, Monique Fabre, Josep M. Llovet, Ramon Planas, Helena Masnou, Piotr Czauderna, María Elena Mateos, Constantino Sábado, Genevieve Laureys, Catherine Guettier, Ricardo López-Almaraz, Claudia Paris, Maria Rosa Sarrias, Montserrat Domingo-Sàbat, Yasmina Mozo, Olga Kuchuk, Marta Garrido, José Javier Uriz, Laura Torrens, Stefano Cairo, Julià Blanco, Gabriela Guillén, Blanca López-Ibor, Sophie Branchereau, Francisco Andrés Pérez Hernández, Daniela Sia, Bojan Losic, Bárbara Torres, Magdalena Arnal, Laura Guerra, Margarita Sala, Laura Royo, Maria Vázquez-Vitali, Gema Ramírez, Núria Villalmanzo, Alberto Villanueva, Ariadna Clos, Mireia Jordà, Nagore García de Andoin, Marina Simon-Coma, Marie Annick Buendia, Juan Carrillo-Reixach, Lauro Sumoy, Sonia Ragull
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Hepatology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
JOURNAL OF HEPATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Universidad de Barcelona
Journal of Hepatology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
JOURNAL OF HEPATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Background & Aims: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the mechanisms of HB pathobiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eda32a593d433d3874ce90c0752929b
http://hdl.handle.net/2445/171912
http://hdl.handle.net/2445/171912
Autor:
Bojan Losic, Delia DʹAvola, Swan N. Thung, Eric E. Schadt, Paula Restrepo, Johann von Felden, Josep M. Llovet, Daniela Sia, Mehmet Eren Ahsen, Stephen C. Ward, Ashley Stueck, Kimaada Allette, Carlos Villacorta-Martin, Gustavo Stolovitzky, Spiros P. Hiotis, Ismail Labgaa, Nicholas K. Akers, Amanda J. Craig, Teresa Garcia-Lezana, Sergio A. Lira, Xintong Chen, Robert Sebra, Sebastiao N. Martins-Filho, Augusto Villanueva, Maria Isabel Fiel, Ganesh Gunasekaran, Myron Schwartz, Glaucia C. Furtado
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Universidad de Barcelona
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Clonal evolution of a tumor ecosystem depends on different selection pressures that are principally immune and treatment mediated. We integrate RNA-seq, DNA sequencing, TCR-seq and SNP array data across multiple regions of liver cancer specimens to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06c1059ab08740960753e706bbbc77a
http://hdl.handle.net/2445/174195
http://hdl.handle.net/2445/174195