Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicholas Jonathan, Cole King"'
Autor:
Jian Tan, Duan Ni, Jemma Taitz, Gabriela Veronica Pinget, Mark Read, Alistair Senior, Jibran Abdul Wali, Reem Elnour, Erin Shanahan, Huiling Wu, Steven J. Chadban, Ralph Nanan, Nicholas Jonathan Cole King, Georges Emile Grau, Stephen J. Simpson, Laurence Macia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Secretory IgA plays vital roles interfacing between the host immune system and the resident microbiota at the mucosal surface. Here the authors explore the effect of dietary protein on the production of secretory IgA, driven by the production of extr
Externí odkaz:
https://doaj.org/article/1a558a672c5147d9bc844ff084a46355
Autor:
Duan Ni, Jian Tan, Paula Niewold, Alanna Gabrielle Spiteri, Gabriela Veronica Pinget, Dragana Stanley, Nicholas Jonathan Cole King, Laurence Macia
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dietary fiber supports healthy gut bacteria and their production of short-chain fatty acids (SCFA), which promote anti-inflammatory cell development, in particular, regulatory T cells. It is thus beneficial in many diseases, including influenza infec
Externí odkaz:
https://doaj.org/article/a8b5ad3dc462415095b1621dcf72f0e4
Autor:
Jian Tan, Duan Ni, Jibran Abdul Wali, Darren Anthony Cox, Gabriela Veronica Pinget, Jemma Taitz, Claire Immediato Daïen, Alistair Senior, Mark Norman Read, Stephen James Simpson, Nicholas Jonathan Cole King, Laurence Macia
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102835- (2021)
Summary: While diet modulates immunity, its impact on B cell ontogeny remains unclear. Using mixture modeling, a large-scale isocaloric dietary cohort mouse study identified carbohydrate as a major driver of B cell development and function. Increasin
Externí odkaz:
https://doaj.org/article/7a5e95ba684f4b70858620e02385dd8d
Autor:
Christina Lai, Steven J. Chadban, Yik Wen Loh, Tony King-Tak Kwan, Chuanmin Wang, Julian Singer, Paula Niewold, Zheng Ling, Alanna Spiteri, Daniel Getts, Nicholas Jonathan Cole King, Huiling Wu
Publikováno v:
Kidney International. 102:1090-1102
Inflammatory monocytes are a major component of the cellular infiltrate in acutely rejecting human kidney allografts. Since immune-modifying nanoparticles (IMPs) bind to circulating inflammatory monocytes via the specific scavenger receptor MARCO, ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a907e3fcb69cec0ec390aaf3380a83
https://doi.org/10.1016/j.kint.2022.06.024
https://doi.org/10.1016/j.kint.2022.06.024
Publikováno v:
Wishart, Claire L; Spiteri, Alanna G; Locatelli, Giuseppe; King, Nicholas J C (2023). Integrating transcriptomic datasets across neurological disease identifies unique myeloid subpopulations driving disease-specific signatures. GLIA, 71(4), pp. 904-925. Wiley-Blackwell 10.1002/glia.24314
Microglia and bone marrow-derived monocytes are key elements of central nervous system (CNS) inflammation, both capable of enhancing and dampening immune-mediated pathology. However, the study-specific focus on individual cell types, disease models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebff6184a54d77098dadd621a2be4df
https://boris.unibe.ch/176034/1/Glia_-_2022_-_Wishart_-_Integrating_transcriptomic_datasets_across_neurological_disease_identifies_unique_myeloid.pdf
https://boris.unibe.ch/176034/1/Glia_-_2022_-_Wishart_-_Integrating_transcriptomic_datasets_across_neurological_disease_identifies_unique_myeloid.pdf
Autor:
Gabriela Veronica Pinget, Jian Kai Tan, Duan Ni, Jemma Taitz, Claire Immediato Daien, Julie Mielle, Robert John Moore, Dragana Stanley, Stephen Simpson, Nicholas Jonathan Cole King, Laurence Macia
Publikováno v:
Cell Reports
Cell Reports, 2022, 40 (7), pp.111191. ⟨10.1016/j.celrep.2022.111191⟩
Cell Reports, 2022, 40 (7), pp.111191. ⟨10.1016/j.celrep.2022.111191⟩
International audience; Psoriasis has long been associated with inflammatory bowel disease (IBD); however, a causal link is yet to be established. Here, we demonstrate that imiquimod-induced psoriasis (IMQ-pso) in mice disrupts gut homeostasis, chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7ec835a4229eb7390ab50171cbd84b
https://pubmed.ncbi.nlm.nih.gov/35977500
https://pubmed.ncbi.nlm.nih.gov/35977500
Autor:
Jian Tan, Duan Ni, Jemma Taitz, Gabriela Veronica Pinget, Mark Read, Alistair Senior, Jibran Abdul Wali, Reem Elnour, Erin Shanahan, Huiling Wu, Steven J. Chadban, Ralph Nanan, Nicholas Jonathan Cole King, Georges Emile Grau, Stephen J. Simpson, Laurence Macia
Publikováno v:
Nature communications. 13(1)
Secretory IgA is a key mucosal component ensuring host-microbiota mutualism. Here we use nutritional geometry modelling in mice fed 10 different macronutrient-defined, isocaloric diets, and identify dietary protein as the major driver of secretory Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cd999d9aa6b190ed6a0ed3d4bafb2d
https://pubmed.ncbi.nlm.nih.gov/35896537
https://pubmed.ncbi.nlm.nih.gov/35896537
Publikováno v:
Frontiers in Immunology, Vol 2 (2011)
Despite their clear relationship to immunology, few existing studies have examined potential role of microparticles (MP) in infectious disease. Infection with pathogens usually leads to the expression of a range of inflammatory cytokines and chemokin
Externí odkaz:
https://doaj.org/article/3739f0ab58894a9a8f2addf0b2d39ede
Autor:
Thomas Myles, Ashhurst, Caryn van, Vreden, Luis, Munoz-Erazo, Paula, Niewold, Kanami, Watabe, Rachael L, Terry, Celine, Deffrasnes, Daniel R, Getts, Nicholas Jonathan, Cole King
Publikováno v:
The Indian Journal of Medical Research
Mosquito-borne flaviviruses are a major current and emerging threat, affecting millions of people worldwide. Global climate change, combined with increasing proximity of humans to animals and mosquito vectors by expansion into natural habitats, coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5826c1bd371f06022fd680cdf079c7b3
https://pubmed.ncbi.nlm.nih.gov/24434318
https://pubmed.ncbi.nlm.nih.gov/24434318
Publikováno v:
Scopus-Elsevier
The murine S100 chemotactic protein of m.w. 10,000 termed (CP-10), has potent chemotactic activity for murine and human myeloid cells. We examined the ability of a synthetic CP-10 hinge region peptide CP-10(42-55) and rCP-10 to act as chemotactic age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a87eb4340b20101c1b2247deb872bd
https://doi.org/10.4049/jimmunol.152.4.1888
https://doi.org/10.4049/jimmunol.152.4.1888