Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicholas J.F. Dodd"'
Autor:
Yuktee Dogra, Daniel C.J. Ferguson, Nicholas J.F. Dodd, Gary R. Smerdon, Alison Curnow, Paul G. Winyard
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 90-99 (2016)
Methyl-aminolevulinate-based photodynamic therapy (MAL-PDT) is utilised clinically for the treatment of non-melanoma skin cancers and pre-cancers and the hydroxypyridinone iron chelator, CP94, has successfully been demonstrated to increase MAL-PDT ef
Externí odkaz:
https://doaj.org/article/571f669eb27b4a2993207cacbb6a1810
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 809:43-49
Auranofin, an organogold compound classified as an anti-rheumatic agent is under phase 2 clinical trials for re-purposing to treat recurrent epithelial ovarian cancer. We have reported earlier that Breast cancer 1, early onset (BRCA1) mutant ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55f3abfa08f8de32b706f3127ae68e1
https://doi.org/10.1016/j.mrgentox.2016.09.003
https://doi.org/10.1016/j.mrgentox.2016.09.003
Autor:
Nga-Chi Yip, Paula M. Mendes, David J. Garrett, Simon K. Jackson, Alison J. Downard, Kim Baronian, Jacqueline M. Hicks, György Fejer, Frankie J. Rawson, Wondwossen Abate, Nicholas J.F. Dodd
Publikováno v:
ACS Applied Materials & Interfaces
Herein, we report a highly sensitive electrocatalytic sensor-cell construct that can electrochemically communicate with the internal environment of immune cells (e.g., macrophages) via the selective monitoring of a particular reactive oxygen species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642116636be9ffbf53855c2e2cf90d1b
http://europepmc.org/articles/PMC4654508
http://europepmc.org/articles/PMC4654508
Autor:
Nicholas J.F. Dodd, Awadhesh N. Jha
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 660:79-82
Titanium dioxide (TiO(2)) nanoparticles have been shown to be genotoxic to cells exposed to ultraviolet A (UVA) radiation. Using the technique of electron spin resonance (ESR) spin trapping, we have confirmed that the primary damaging species produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19cd938da682d2b5dd65e007ec7508b
https://doi.org/10.1016/j.mrfmmm.2008.10.007
https://doi.org/10.1016/j.mrfmmm.2008.10.007
Publikováno v:
International Journal of Food Science & Technology. 27:371-383
Summary The exposure of foodstuffs containing bone or other calcified tissue to a dose of ionizing radiation results in the formation of long lived free radicals which give rise to characteristic ESR signals. The presence of this signal provides clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93493d03db5a9fef9b524fa93652451c
https://doi.org/10.1111/j.1365-2621.1992.tb01202.x
https://doi.org/10.1111/j.1365-2621.1992.tb01202.x
Autor:
Laura M. Langan, Nicholas J.F. Dodd, Awadhesh N. Jha, Wendy M. Purcell, Simon K. Jackson, Stewart F. Owen
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149492 (2016)
PLoS ONE
PLoS ONE
Advanced in vitro culture from tissues of different origin includes three-dimensional (3D) organoid micro structures that may mimic conditions in vivo. One example of simple 3D culture is spheroids; ball shaped structures typically used as liver and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6238c1f53fd848c485013a778f999af6
https://doi.org/10.1371/journal.pone.0149492
https://doi.org/10.1371/journal.pone.0149492
Autor:
Awadhesh N. Jha, Nicholas J.F. Dodd
Publikováno v:
Photochemistry and photobiology. 87(3)
It is well-established that exposure of aqueous suspensions of titanium dioxide (TiO(2)) nanoparticles to ultraviolet A (UVA) light produces reactive oxygen species which leads to biological damage. However, there is disagreement in the literature as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7795b6f2907f8eae72386a8d9cdab7
https://pubmed.ncbi.nlm.nih.gov/21244435
https://pubmed.ncbi.nlm.nih.gov/21244435
Publikováno v:
Mutation research. 640(1-2)
TiO(2) nanoparticles (< 100 nm diameter) have been reported to cause oxidative stress related effects, including inflammation, cytotoxicity and genomic instability, either alone or in the presence of UVA irradiation in mammalian studies. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c77559951b4f5ce6fc235b084001cfe
https://pubmed.ncbi.nlm.nih.gov/18258270
https://pubmed.ncbi.nlm.nih.gov/18258270
Publikováno v:
Carcinogenesis. 21(1)
Ethanol was given to male Wistar rats as an acute dose (5 g/kg) or continuously at 5% (w/v) in a liquid diet to provide 36% of the caloric requirement. Free radicals generated in the liver were collected as a stable adduct in bile following the in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf97c94d2bfc699209f61f8c3b58450a
https://pubmed.ncbi.nlm.nih.gov/10607739
https://pubmed.ncbi.nlm.nih.gov/10607739
Autor:
J. M. Bruce, C. Lambert, S. P. McNeeney, I. Hamblett, Anthony A. Gorman, Nicholas J.F. Dodd, C. W. Kerr
Publikováno v:
Photochemistry and photobiology. 52(2)
The singlet and triplet states of the anthralin (1,8-dihydroxy-9-anthrone) dehydrodimer have been produced selectively in benzene via pulsed laser excitation and pulse radiolysis respectively. The lifetime of S1 is less than or equal to 30 ps, that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3806e4d5914bf71b9b3d740f2ba6a14c
https://pubmed.ncbi.nlm.nih.gov/2217548
https://pubmed.ncbi.nlm.nih.gov/2217548