Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nicholas J. Santistevan"'
Autor:
Richard D. Smrt, Julialea Eaves-Egenes, Basam Z. Barkho, Nicholas J. Santistevan, Chunmei Zhao, James B. Aimone, Fred H. Gage, Xinyu Zhao
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 1, Pp 77-89 (2007)
It is well known that Rett Syndrome, a severe postnatal childhood neurological disorder, is mostly caused by mutations in the MECP2 gene. However, how deficiencies in MeCP2 contribute to the neurological dysfunction of Rett Syndrome is not clear. We
Externí odkaz:
https://doaj.org/article/1be05c33e93e45438572ea91f30aa969
Autor:
Nicholas J Santistevan, Jessica C Nelson, Elelbin A Ortiz, Andrew H Miller, Dima Kenj Halabi, Zoë A Sippl, Michael Granato, Yevgenya Grinblat
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270903 (2022)
BackgroundThe ability to filter sensory information into relevant versus irrelevant stimuli is a fundamental, conserved property of the central nervous system and is accomplished in part through habituation learning. Synaptic plasticity that underlie
Externí odkaz:
https://doaj.org/article/05f8398aaf7949c8b8514d58c4b3b85a
Autor:
Yujing Li, Yuping Luo, Peng Jin, Keith E. Szulwach, Nicholas J. Santistevan, Wendi Li, Xuekun Li, Xinyu Zhao, Li Lin, Richard D. Smrt
Publikováno v:
The Journal of Cell Biology
The microRNA miR-137 represses expression of Ezh2, a histone methyltransferase, which in turn alters the epigenetic architecture of chromatin that is important for regulation of miR-137 levels.
Both microRNAs (miRNAs) and epigenetic regulation h
Both microRNAs (miRNAs) and epigenetic regulation h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6853806d24373a033160f3b643c4492b
https://doi.org/10.1083/jcb.200908151
https://doi.org/10.1083/jcb.200908151
Autor:
Hongda Li, Qiang Chang, Peng Jin, Guangyao Kong, Jamie Masliah, Jingyi Chi, Xinyu Zhao, Xuekun Li, Nicholas J. Santistevan, Weixiang Guo, Jing Zhang, Kevin F. Chau, Xiaofen Zhong, Mitul Kadakia
Publikováno v:
Nature Communications
Nature Communications, 2013, 5, pp.5601. ⟨10.1038/ncomms6601⟩
Nature Communications, Nature Publishing Group, 2013, 5, pp.5601. ⟨10.1038/ncomms6601⟩
Nature communications
Nature Communications, 2013, 5, pp.5601. ⟨10.1038/ncomms6601⟩
Nature Communications, Nature Publishing Group, 2013, 5, pp.5601. ⟨10.1038/ncomms6601⟩
Nature communications
International audience; Neuronal activity regulates the phosphorylation states at multiple sites on MeCP2 in postmitotic neurons. The precise control of the phosphorylation status of MeCP2 in neurons is critical for the normal development and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f0bbbe57107d442e7177c502bacb83
https://doi.org/10.1038/ncomms6601
https://doi.org/10.1038/ncomms6601
Autor:
Keith E. Szulwach, Zhao-Qian Teng, Xinyu Zhao, Weixiang Guo, Chang-Mei Liu, Nicholas J. Santistevan, Peng Jin
Summary Methyl-CpG binding protein 1 (MBD1) regulates gene expression via a DNA methylation-mediated epigenetic mechanism. We have previously demonstrated that MBD1 deficiency impairs adult neural stem/progenitor cell (aNSC) differentiation and neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b13fc91a79ed4f8a7cd60ad0c37f71
https://europepmc.org/articles/PMC2867837/
https://europepmc.org/articles/PMC2867837/
Autor:
Tomoko Kuwabara, Basam Z. Barkho, Yuping Luo, Nicholas J. Santistevan, Richard D. Smrt, Xuekun Li, Fred H. Gage, Jinfeng Bao, Chang-Mei Liu, Xinyu Zhao
Dr. Bao's name was inadvertently omitted from the list of authors. The correct author list is shown above. Dr. Bao's affiliation is as follows: Department of Pharmacology, Xuzhou Medical College, Tongshan Road 209, Xuzhou 221004, Jiangsu Province, Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ab5c2160beaba2691f0b9004e2adc8
https://europepmc.org/articles/PMC2659258/
https://europepmc.org/articles/PMC2659258/
Autor:
Chang-Mei Liu, Fred H. Gage, Xuekun Li, Basam Z. Barkho, Yuping Luo, Nicholas J. Santistevan, Tomoko Kuwabara, Xinyu Zhao, Richard D. Smrt
Whether and how mechanisms intrinsic to stem cells modulate their proliferation and differentiation are two central questions in stem cell biology. Although exogenous basic fibroblast growth factor 2 (FGF-2/Fgf-2) is commonly used to expand adult neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e76b34046a121a866d0f55350239b3d
https://europepmc.org/articles/PMC2562066/
https://europepmc.org/articles/PMC2562066/
Autor:
Nicholas J. Santistevan, Basam Z. Barkho, Chunmei Zhao, Fred H. Gage, James B. Aimone, Xinyu Zhao, Julialea Eaves-Egenes, Richard D. Smrt
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 1, Pp 77-89 (2007)
It is well known that Rett Syndrome, a severe postnatal childhood neurological disorder, is mostly caused by mutations in the MECP2 gene. However, how deficiencies in MeCP2 contribute to the neurological dysfunction of Rett Syndrome is not clear. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5be0be31dde667e5db434bb6a6857e
https://pubmed.ncbi.nlm.nih.gov/17532643
https://pubmed.ncbi.nlm.nih.gov/17532643
Publikováno v:
Retrovirology, Vol 8, Iss 1, p 51 (2011)
Retrovirology
Retrovirology
Background The process of HIV-1 genomic RNA (gRNA) encapsidation is governed by a number of viral encoded components, most notably the Gag protein and gRNA cis elements in the canonical packaging signal (ψ). Also implicated in encapsidation are cis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2becffaf67b9d7b7721bcc9bef21155