Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Nicholas J. Saner"'
Autor:
Hayley T. Dillon, Nicholas J. Saner, Tegan Ilsley, David Kliman, Andrew Spencer, Sharon Avery, David W. Dunstan, Robin M. Daly, Steve F. Fraser, Neville Owen, Brigid M. Lynch, Bronwyn A. Kingwell, Andre La Gerche, Erin J. Howden
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Allogeneic stem cell transplantation (allo-SCT) is a potentially lifesaving treatment for high-risk hematological malignancy, but survivors experience markedly elevated rates of cardiovascular disease and associated functional imp
Externí odkaz:
https://doaj.org/article/d44a5fe4ff3d4b5b81d1ece04e1c8fb9
Autor:
Wentao Lin, Nicholas J. Saner, Xiquan Weng, Nikeisha J. Caruana, Javier Botella, Jujiao Kuang, Matthew J-C. Lee, Nicholas A. Jamnick, Nathan W. Pitchford, Andrew Garnham, Jonathan D. Bartlett, Hao Chen, David J. Bishop
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundInadequate sleep is associated with many detrimental health effects, including increased risk of developing insulin resistance and type 2 diabetes. These effects have been associated with changes to the skeletal muscle transcriptome, althou
Externí odkaz:
https://doaj.org/article/a65559c78c7846f6a08296df303c8f7e
Autor:
Jujiao Kuang, Cian McGinley, Matthew J-C Lee, Nicholas J. Saner, Andrew Garnham, David J. Bishop
Publikováno v:
PeerJ, Vol 10, p e12856 (2022)
Background Exercise elicits a range of adaptive responses in skeletal muscle, which include changes in mRNA expression. To better understand the health benefits of exercise training, it is important to investigate the underlying molecular mechanisms
Externí odkaz:
https://doaj.org/article/457fa5b2fffd49bab5cf527bcd703d27
Autor:
Amanda J. Genders, Evelyn C. Marin, Joseph J. Bass, Jujiao Kuang, Nicholas J. Saner, Ken Smith, Philip J. Atherton, David J. Bishop
Publikováno v:
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Aim Exercise is able to increase both muscle protein synthesis and mitochondrial biogenesis. However, acidosis, which can occur in pathological states as well as during high‐intensity exercise, can decrease mitochondrial function, whilst i
Externí odkaz:
https://doaj.org/article/22fe5f480d4b4b00aa34f08a27a6eab9
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C67-C75
Exercise training can increase both mitochondrial content and mitochondrial respiration. Despite its popularity, high-intensity exercise can be accompanied by mild acidosis (also present in certain pathological states), which may limit exercise-induc
Publikováno v:
American Journal of Physiology-Cell Physiology. 322:C461-C467
As the principal energy-producing organelles of the cell, mitochondria support numerous biological processes related to metabolism, growth, and regeneration in skeletal muscle. Deterioration in skeletal muscle functional capacity with age is thought
Autor:
Evelyn C. Marin, Victor Amorim Andrade-Souza, Nicholas J. Saner, Glenn K. McConell, Amanda J Genders, Macsue Jacques, David Bishop, Javier Chagolla, Jujiao Kuang, Javier Botella
Publikováno v:
Journal of Endocrinology. 252:91-105
The aim of this study was to investigate the relationship between mitochondrial content and respiratory function and whole-body insulin resistance in high-fat diet (HFD) fed rats. Male Wistar rats were given either a chow diet or an HFD for 12 weeks.
Autor:
Michael D. Flannery, Leah Wright, Nicholas J. Saner, David Griffin, A. Lindqvist, Andrew Garnham, Erin H Howden, Ben Costello, Brian Cowie, Rachel E. Climie, Steve Foulkes, Daniel J. Green, K. Janssens, Andre La Gerche, Imogen Wallace, Elizabeth D Paratz, Amy Mitchell
Publikováno v:
European Journal of Preventive Cardiology
[Extract] We recruited every player from a squad of professional basketballers involved in a ‘super-spreader’ event that lead to a majority being infected with COVID-19 following a single training session in Melbourne, Australia. We compared thos
Publikováno v:
The Journal of Physiology. 599:3463-3476
Mitochondria are dynamic organelles, intricately designed to meet cellular energy requirements. To accommodate alterations in energy demand, mitochondria have a high degree of plasticity, changing in response to transient activation of numerous stres
Autor:
Boon Siang Nicholas Tan, Joly Kwek, Chong Kum Edwin Wong, Nicholas J Saner, Charlotte Yap, Fernando Felquer, Michael B Morris, David K Gardner, Peter D Rathjen, Joy Rathjen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163244 (2016)
Multiple pluripotent cell populations, which together comprise the pluripotent cell lineage, have been identified. The mechanisms that control the progression between these populations are still poorly understood. The formation of early primitive ect
Externí odkaz:
https://doaj.org/article/bdda700d644b4543996b3a3770dcdcaa