Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nicholas J. Rotile"'
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is an increasing cause of chronic liver disease characterized by steatosis, inflammation, and fibrosis which can lead to cirrhosis, hepatocellular carcinoma, and mortality. Quantitative, noninvasive metho
Externí odkaz:
https://doaj.org/article/327b39d031bd46df9de3f4c4aba0cf0e
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5dff62519d184cbbbad8e11434fc02ef
Autor:
Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs
Publikováno v:
Hepatology Communications, Vol 2, Iss 7, Pp 821-835 (2018)
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic reso
Externí odkaz:
https://doaj.org/article/3b4760b0fefd4d1697564907fb1c9f1f
Autor:
Lixiong Dai, Chloe M. Jones, Wesley Ting Kwok Chan, Tiffany A. Pham, Xiaoxi Ling, Eric M. Gale, Nicholas J. Rotile, William Chi-Shing Tai, Carolyn J. Anderson, Peter Caravan, Ga-Lai Law
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
MRI contrast agents containing the rare earth metal gadolinium are very effective, yet unstable and thus potentially hazardous. Here, the authors developed complexes between gadolinium and the scaffolding compound DOTA with increased stability, which
Externí odkaz:
https://doaj.org/article/b3f0ee3971b54efaad568f148589af0b
Autor:
Shadi A. Esfahani, Carolina de Aguiar Ferreira, Nicholas J. Rotile, Bahar Ataeinia, Shriya Krishna, Onofrio A. Catalano, Peter Caravan, Yi-Fen Yen, Pedram Heidari, Umar Mahmood
Publikováno v:
Mol Imaging Biol
PURPOSE: New generation of receptor tyrosine kinase inhibitors (RTKIs) have shown to improve survival in many solid tumors. However, an imaging biomarker is needed for patient selection and prediction of treatment response. This study evaluates the u
Autor:
Yin-Ching Chen, Philip A. Waghorn, Ivy A. Rosales, Gunisha Arora, Derek J. Erstad, Nicholas J. Rotile, Chloe M. Jones, Diego S. Ferreira, Lan Wei, Robert V. P. Martinez, Franklin J. Schlerman, Jeremy Wellen, Bryan C. Fuchs, Robert B. Colvin, Ilknur Ay, Peter Caravan
Publikováno v:
Journal of the American Society of Nephrology.
Autor:
Juanye Zhang, Yingying Ning, Hua Zhu, Nicholas J. Rotile, He Wei, Himashinie Diyabalanage, Eric C. Hansen, Iris Y. Zhou, Stephen C. Barrett, Mozhdeh Sojoodi, Kenneth K. Tanabe, Valerie Humblet, Alan Jasanoff, Peter Caravan, Moungi G. Bawendi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
SNIO–CBP, a single-nanometer iron oxide (SNIO) nanoparticle functionalized with a type I collagen-binding peptide (CBP), was developed as a T 1 -weighted MRI contrast agent with only endogenous elements for fast and noninvasive detection of liver f
Tailored chemical reactivity probes for systemic imaging of aldehydes in fibroproliferative diseases
Autor:
Hua Ma, Iris Y. Zhou, Y. Iris Chen, Nicholas J. Rotile, Ilknur Ay, Eman Akam, Huan Wang, Rachel Knipe, Lida P. Hariri, Caiyuan Zhang, Matthew Drummond, Pamela Pantazopoulos, Brianna F. Moon, Avery T. Boice, Samantha E. Zygmont, Jonah Weigand-Whittier, Mozhdeh Sojoodi, Romer A. Gonzalez-Villalobos, Michael K. Hansen, Kenneth K. Tanabe, Peter Caravan
Publikováno v:
bioRxiv
During fibroproliferation, protein-associated extracellular aldehydes are formed by the oxidation of lysine residues on extracellular matrix proteins to form the aldehyde allysine. Here we report three Mn(II)-based, small molecule magnetic resonance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d774103a098f16a85a8a9c60f945cf
https://doi.org/10.1101/2023.04.20.537707
https://doi.org/10.1101/2023.04.20.537707
Autor:
Bryan C. Fuchs, Peter Caravan, Kenneth K. Tanabe, Michael Lanuti, Cristina R. Ferrone, Nabeel Bardeesy, Motaz Qadan, Vikram Deshpande, Valerie Humblet, Gunisha Arora, Yin-Ching Iris Chen, Sarani Ghoshal, Shen Li, Akhil Chawla, Filippos Kontos, Theodoros Michelakos, Diego S. Ferreira, Katherine A. Graham-O'Regan, Chloe Jones, Nicholas J. Rotile, Andrea L. Axtell, Christian T. Farrar, Veronica Clavijo Jordan, Martin S. Taylor, Mozhdeh Sojoodi, Derek J. Erstad
Supplementary Legends, Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc790b80da8f6a8f35733cec0b87d72
https://doi.org/10.1158/1078-0432.22467480
https://doi.org/10.1158/1078-0432.22467480
Autor:
Bryan C. Fuchs, Peter Caravan, Kenneth K. Tanabe, Michael Lanuti, Cristina R. Ferrone, Nabeel Bardeesy, Motaz Qadan, Vikram Deshpande, Valerie Humblet, Gunisha Arora, Yin-Ching Iris Chen, Sarani Ghoshal, Shen Li, Akhil Chawla, Filippos Kontos, Theodoros Michelakos, Diego S. Ferreira, Katherine A. Graham-O'Regan, Chloe Jones, Nicholas J. Rotile, Andrea L. Axtell, Christian T. Farrar, Veronica Clavijo Jordan, Martin S. Taylor, Mozhdeh Sojoodi, Derek J. Erstad
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7baea5c7db506252070b50fbe9a5e8
https://doi.org/10.1158/1078-0432.22467483
https://doi.org/10.1158/1078-0432.22467483