Dual-Catalytic Enantioselective Allylation of

Autor: Sangyun, Kim, Annika D S, Richardson, Atanu, Modak, Nicholas J, Race

Publikováno v: The Journal of organic chemistry.

We report the dual-catalytic enantioselective allylic alkylation of 2-(pyridylmethyl)amine-derived ketimines with allylic carbonates. The reaction proceeds under mild reaction conditions to generate α-amino heteroaryl benzylamine stereocenters in go

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c881eec0b40c44a5be5f3e9f3dcbc038
https://pubmed.ncbi.nlm.nih.gov/36562778

Revisiting the ‘Phenonium Phenomenon’: Regiodivergent Opening of Nonsymmetrical Phenonium Ions with Halide Nucleophiles

Autor: Shelby B. McGuire, Nicholas J. Race, Hannah M. Holst

Publikováno v: Synlett. 32:01-06

Formation of phenonium ions through anchimeric assistance (neighboring-group participation) of aryl rings has been known since 1949. Although these reactive intermediates have been studied extensively by physical organic chemists, their potential as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::841ee64f051ba193842bf53a597cf0f0
https://doi.org/10.1055/s-0040-1706420

Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles

Autor: Nicholas J. Race, Adele Faulkner, Ian R. Hazelden, John F. Bower

Publikováno v: Chemical Science
Race, N J, Hazelden, I R, Faulkner, A & Bower, J F 2017, ' Recent developments in the use of aza-Heck cyclizations for the synthesis of chiral N-heterocycles ', Chemical Science, vol. 8, no. 8, pp. 5248-5260 . https://doi.org/10.1039/c7sc01480e

The scope and mechanism of aza-Heck methodologies that provide chiral heterocyclic systems are outlined.
Aza-Heck cyclizations are an emerging method for the construction of chiral N-heterocyclic systems. In these processes, an activated N–O b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c285c9af707b3f13b27711014ddad370
http://europepmc.org/articles/PMC5606024

Dichotomous mechanistic behavior in Narasaka–Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals

Autor: John F. Bower, Nicholas J. Race, Adele Faulkner, Megan H. Shaw

Publikováno v: Race, N J, Faulkner, A, Shaw, M H & Bower, J 2016, ' Dichotomous mechanistic behaviour in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals ', Chemical Science, vol. 7, no. 2, pp. 1508-1513 . https://doi.org/10.1039/C5SC04037J
Chemical Science

Pd-catalyzed cyclizations of oxime esters with pendant alkenes undergo ligand controlled mechanistic divergence. Electron deficient phosphines promote aza-Heck cyclization; electron rich systems favour a SET pathway. Mechanistic experiments different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a09ac5d93b7d9f29f2861edd717cf32
https://doi.org/10.1039/c5sc04037j

Catalytic Oxidation in Organic Synthesis

Autor: N. Rodríguez, J.-P. Lumb, T. M. Leuther, A. C. Wright, Anna Andries-Ulmer, Takao Ikariya, C. Gimbert-Suriñach, Kazuaki Ishihara, P. Calleja, R. Dorel, Z. Li, B. M. Stoltz, G. Liu, F. Bellina, L. A. Perego, L. M. Dornan, P. J. Pérez, Fateh V. Singh, N. L. Hughes, Matthew S. Sigman, N. Jiao, M. J. Muldoon, Muhammet Uyanik, M. Borrell, Kilian Muñiz, R. Gómez-Arrayas, Pau Farràs, D. C. Ebner, T. Wdowik, M. M. Díaz-Requejo, Antoni Llobet, A. Caballero, Nicholas J. Race, Hauke Engler, Yoshihito Kayaki, S. R. Chemler, Thomas Wirth, I. Funes-Ardoiz, P. Chen, Pablo Garrido-Barros, Harshkumar H. Patel, K. V. N. Esguerra, Tanja Gulder, N. Park, L. Vicens, Miquel Costas, A. M. Echavarren, S. Sillner, Claudio Martínez, Albrecht Berkessel, A. G. Griesbeck, M. Kleczka, F. Maseras

Publikováno v: Science of Synthesis ISBN: 9783132403710
Catalytic Oxidation in Organic Synthesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41e4590745a984aa3d12cc2147b0527f
https://doi.org/10.1055/b-003-129345