Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicholas J. Kuehl"'
Autor:
Caleb R. Hoopes, Francisco J. Garcia, Akash M. Sarkar, Nicholas J. Kuehl, David T. Barkan, Nicole L. Collins, Glenna E. Meister, Taylor R. Bramhall, Chien-Hsiang Hsu, Michael D. Jones, Markus Schirle, Michael T. Taylor
Publikováno v:
J Am Chem Soc
Tryptophan (Trp) plays a variety of critical functional roles in protein biochemistry however, owing to its low natural frequency and poor nucleophilicity, the design of effective methods for both single protein bioconjugation at Trp as well as for i
Autor:
Michael D. Jones, Francisco J. Garcia, David T. Barkan, Nicole Collins, Chien-Hsang Hsu, Caleb Hoopes, Nicholas J. Kuehl, Michael T. Taylor, Markus Schirle, Akash Sarkar
Tryptophan (Trp) plays a variety of critical functional roles in protein biochemistry however, owing to its low natural frequency and poor nucleophilicity, the design of effective methods for both single protein bioconjugation at Trp as well as for i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3a52a2cdc1f4ca70f722fd88e0750c
https://doi.org/10.33774/chemrxiv-2021-r2nd2
https://doi.org/10.33774/chemrxiv-2021-r2nd2
Publikováno v:
J Am Chem Soc
We report here a photochemical process for the selective modification of tryptophan (Trp) residues in peptides and small proteins using electron-responsive N-carbamoylpyridinium salts and UV-B light. Preliminary mechanistic experiments suggest that t