Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nicholas J. DelRaso"'
Publikováno v:
Chemical Research in Toxicology. 32:265-284
Previously, we demonstrated that treatment of rats with myo-inositol plus ethanolamine (ME) elevated brain ethanolamine plasmalogens (PE-Pls) and protected against phosphine-induced oxidative stress. Here we tested the hypothesis that ME treatment el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6020474794abff38cdc281645ea100ad
https://doi.org/10.1021/acs.chemrestox.8b00280
https://doi.org/10.1021/acs.chemrestox.8b00280
Autor:
Nicholas J. DelRaso, Mari L. Chamberlain, Paul E. Anderson, Donald L. Harville, Nicholas V. Reo, Michael L. Raymer, Isaie Sibomana
Publikováno v:
Current Metabolomics. 4:63-77
Background: Continuous and sustained actions in military and civilian operational environments typically lead to reduced sleep normally required to perform optimally. Because cognitive fatigue leading to defects in performance is an occupational haza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a9c664aa68d0b195050da7cc8c9db9
https://doi.org/10.2174/2213235x04666151117211154
https://doi.org/10.2174/2213235x04666151117211154
Publikováno v:
Military Medicine. 180:67-75
Integrated Omics research capabilities within the Air Force Research Laboratory began in 2003 with the initiation of a Defense Technology Objective project aimed to identify biomarkers of toxicity occurring within the warfighter as a preclinical indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031070d4cd1a68c31e5fe1b6b3b5989c
https://doi.org/10.7205/milmed-d-15-00051
https://doi.org/10.7205/milmed-d-15-00051
Publikováno v:
Metabolomics. 13
The ability of urinary metabolomics to detect meaningful, tissue-specific, biological effects (i.e., toxicity, disease) is compounded by high background variability. We hypothesize that sensitivity can be enhanced by imposing a tissue-targeted metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fa91995eb90ddc36dd887ad9ffc5a2
https://doi.org/10.1007/s11306-017-1162-6
https://doi.org/10.1007/s11306-017-1162-6
Autor:
Nicholas J. DelRaso, Travis E. Doom, Deirdre A. Mahle, Paul E. Anderson, Michael L. Raymer, Nicholas V. Reo
Publikováno v:
Metabolomics. 7:179-190
The interpretation of nuclear magnetic resonance (NMR) experimental results for metabolomics studies requires intensive signal processing and multivariate data analysis techniques. A key step in this process is the quantification of spectral features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b5bb05e9c8f4e852b7ab1d1f9dc9f0
https://doi.org/10.1007/s11306-010-0242-7
https://doi.org/10.1007/s11306-010-0242-7
Autor:
Nicholas J. DelRaso, Deirdre A. Mahle, Nicholas V. Reo, Michael L. Raymer, Paul E. Anderson, Andrew Neuforth
Publikováno v:
Metabolomics. 7:206-216
As metabolomic technology expands, validated techniques for analyzing highly dimensional categorical data are becoming increasingly important. This manuscript presents a novel latent vector-based methodology for analyzing complex data sets with multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f07ec1504fddf930d563173d9669d4
https://doi.org/10.1007/s11306-010-0246-3
https://doi.org/10.1007/s11306-010-0246-3
Autor:
Nicholas J. DelRaso, Nicholas V. Reo, Lyle D. Burgoon, Michael N. Kent, Gary L. Jahns, Timothy R. Zacharewski
Publikováno v:
Metabolomics. 5:253-262
Metabolomics offers the potential to assess the effects of toxicants on metabolite levels. To fully realize this potential, a robust analytical workflow for identifying and quantifying treatment-elicited changes in metabolite levels by nuclear magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9400ff202139ca4d511ed5e3bdf8f6df
https://doi.org/10.1007/s11306-008-0148-9
https://doi.org/10.1007/s11306-008-0148-9
Publikováno v:
Metabolomics. 4:261-272
In many metabolomics studies, NMR spectra are divided into bins of fixed width. This spectral quantification technique, known as uniform binning, is used to reduce the number of variables for pattern recognition techniques and to mitigate effects fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d9b00c2fc7a5ac3fca3c481d12e77b
https://doi.org/10.1007/s11306-008-0117-3
https://doi.org/10.1007/s11306-008-0117-3
Publikováno v:
Toxicological Sciences. 72:19-30
The relationship between cytotoxicity and kinetics of cadmium uptake was investigated in primary rat hepatocyte cultures. Primary rat hepatocytes were exposed to cadmium concentrations ranging from 1.0 to 80 micro M in albumin-free buffer or 32 to 8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdfde1caf2a3c28bac4bd25d1fb8f56
https://doi.org/10.1093/toxsci/kfg009
https://doi.org/10.1093/toxsci/kfg009
Autor:
Agnes L. Forgacs, Meghan K. Makley, Nicholas V. Reo, Nicholas J. DelRaso, Gary L. Jahns, Michael N. Kent, Lyle D. Burgoon, Timothy R. Zacharewski, Bryan D. Mets
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that elicits a broad spectrum of biochemical and toxic effects in a species-specific manner. These effects include hepatotoxicity, immunotoxicity, endocrine disrupti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c129f5dd4f2b61b4c43acfafcb032f8
https://europepmc.org/articles/PMC3243745/
https://europepmc.org/articles/PMC3243745/
