Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Nicholas J. Brooks"'
Autor:
Miguel Paez-Perez, Aurimas Vyšniauskas, Ismael López-Duarte, Eulalie J. Lafarge, Raquel López-Ríos De Castro, Carlos M. Marques, André P. Schroder, Pierre Muller, Christian D. Lorenz, Nicholas J. Brooks, Marina K. Kuimova
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Lipid peroxidation plays an important role in cell signaling and disease as well as therapy, however, the effect on the membrane structure and mechanical behavior remains poorly understood. Here, the authors report the direct and quantitative measure
Externí odkaz:
https://doaj.org/article/d618ddc1b84b4c35a0f7ed7d5c970bc3
Autor:
Marta Salvador-Castell, Maksym Golub, Nelli Erwin, Bruno Demé, Nicholas J. Brooks, Roland Winter, Judith Peters, Philippe M. Oger
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
By studying the properties of a synthetic membrane mimicking an archaeal membrane and containing the apolar polyisoprenoid squalane, Salvador-Castell et al. show that lipid bilayer stability and functionality are shifted to higher temperatures under
Externí odkaz:
https://doaj.org/article/0270c3c5a2ae48b6946e16be5ee4bfc1
Autor:
Anaïs Menny, Marina Serna, Courtney M. Boyd, Scott Gardner, Agnel Praveen Joseph, B. Paul Morgan, Maya Topf, Nicholas J. Brooks, Doryen Bubeck
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The complement membrane attack complex (MAC) is a lytic immune pore that kills pathogens. Here the authors use cryoEM to provide a structural and biophysical mechanism for how β-pore forming proteins breach the lipid bilayer, providing pathways to e
Externí odkaz:
https://doaj.org/article/4bd0eaed6b53416380fc69476cf0e63b
Autor:
Guido Bolognesi, Mark S. Friddin, Ali Salehi-Reyhani, Nathan E. Barlow, Nicholas J. Brooks, Oscar Ces, Yuval Elani
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Assembly of higher-order artificial vesicles can unlock new applications. Here, the authors use optical tweezers to construct user-defined 2D and 3D architectures of chemically distinct vesicles and demonstrate inter-vesicle communication and light-e
Externí odkaz:
https://doaj.org/article/f15abfd0631c43129e22a51a8edbb714
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6087 (2021)
The modification of archaeal lipid bilayer properties by the insertion of apolar molecules in the lipid bilayer midplane has been proposed to support cell membrane adaptation to extreme environmental conditions of temperature and hydrostatic pressure
Externí odkaz:
https://doaj.org/article/fd199071254748deb5f8766e4375ea21
Autor:
Arwen I. I. Tyler, Jake L. Greenfield, John M. Seddon, Nicholas J. Brooks, Sowmya Purushothaman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Biological membranes constantly modulate their fluidity for proper functioning of the cell. Modulation of membrane properties via regulation of fatty acid composition has gained a renewed interest owing to its relevance in endocytosis, endoplasmic re
Externí odkaz:
https://doaj.org/article/951783597f774144916bfb5f73ae08dc
Autor:
Nicholas J. Brooks
Publikováno v:
IUCrJ, Vol 1, Iss 6, Pp 470-477 (2014)
Membranes are amongst the most important biological structures; they maintain the fundamental integrity of cells, compartmentalize regions within them and play an active role in a wide range of cellular processes. Pressure can play a key role in prob
Externí odkaz:
https://doaj.org/article/00bfcb533d18484db8e586ccfe05bb40
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1369-1377 (2013)
Pore-forming proteins containing the structurally conserved membrane attack complex/perforin fold play an important role in immunity and host-pathogen interactions. Intermedilysin (ILY) is an archetypal member of a cholesterol-dependent cytolysin sub
Externí odkaz:
https://doaj.org/article/9efc4171eaf14c4b995d3f729f6d0f50
Publikováno v:
Physical Chemistry Chemical Physics. 25:6316-6325
Physical properties and nanostructuring of ionic liquids show significant differences even in groups of structural isomers.
Lipid membranes are crucial for cellular integrity and regulation, and tight control of their structural and mechanical properties is vital to ensure that they function properly. Fluorescent probes sensitive to the mem-brane’s microenvironment are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50105bc7f90de56488bc672e5873ae8c
https://doi.org/10.26434/chemrxiv-2023-nz4bt-v2
https://doi.org/10.26434/chemrxiv-2023-nz4bt-v2