Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nicholas J Wilson"'
Autor:
William A Figgett, Katherine Monaghan, Milica Ng, Monther Alhamdoosh, Eugene Maraskovsky, Nicholas J Wilson, Alberta Y Hoi, Eric F Morand, Fabienne Mackay
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract Objectives Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that is difficult to treat. There is currently no optimal stratification of patients with SLE, and thus, responses to available treatments are unpredictable.
Externí odkaz:
https://doaj.org/article/24ce743335bc4a30b9ded20c32a67a96
Autor:
Shereen Oon, Katherine Monaghan, Milica Ng, Alberta Hoi, Eric Morand, Gino Vairo, Eugene Maraskovsky, Andrew D Nash, Ian P Wicks, Nicholas J Wilson
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract Objectives Plasmacytoid dendritic cells (pDCs), through the production of type 1 interferons (IFNs) and other cytokines, are major contributors to systemic lupus erythematosus (SLE) pathogenesis. IL‐3 promotes pDC survival, but its role in
Externí odkaz:
https://doaj.org/article/dc33ae9259a9457d941114886e24feff
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 17, Pp n/a-n/a (2023)
Abstract Antarctic ice shelves are losing mass at increasing rates, yet the ice‐ocean interactions that cause significant ice loss are not well understood. A new approach of high‐resolution phase‐change simulations is used to model vertical ice
Externí odkaz:
https://doaj.org/article/95f7b875ff1b4f59ac4e0e2c0b8f3711
Publikováno v:
Australian Journal of Psychology, Vol 72, Iss 2, Pp 211-222 (2020)
Objectives The aims of the present study are to investigate (a) whether a control task (i.e., the grocery imagery task) classically used in emotion research and designed to emulate emotional neutrality is truly neutral and (b) how boredom proneness,
Externí odkaz:
https://doaj.org/article/8a2377ab08d34e1497b70c6f8bf822f4
Autor:
Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Winnie L. Kan, Emma F. Barry, Mara Dottore, Karen S. Cheung Tung Shing, Craig J. Morton, Urmi Dhagat, Matthew P. Hardy, Nicholas J. Wilson, Matthew T. Downton, Christine Schieber, Timothy P. Hughes, Angel F. Lopez, Michael W. Parker
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The N-terminal domain (NTD) of interleukin-3 receptor α-subunit (IL3Rα) is involved in IL-3 recognition but the underlying mechanism is unknown. Here, the authors present crystal structures of the IL3Rα complex and provide biochemical evidence tha
Externí odkaz:
https://doaj.org/article/a177e8976263487282e8d1895527256b
Autor:
Sophie E. Broughton, Timothy R. Hercus, Matthew P. Hardy, Barbara J. McClure, Tracy L. Nero, Mara Dottore, Huy Huynh, Hal Braley, Emma F. Barry, Winnie L. Kan, Urmi Dhagat, Pierre Scotney, Dallas Hartman, Samantha J. Busfield, Catherine M. Owczarek, Andrew D. Nash, Nicholas J. Wilson, Michael W. Parker, Angel F. Lopez
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 410-419 (2014)
Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Here, we report the crystal structure of the IL-3 receptor α chain (IL3Rα) in complex with the anti-leukemia
Externí odkaz:
https://doaj.org/article/06924e2c5a1a4bf8928942626539913b
Autor:
Jonathan L. McQualter, Christian Aloe, Steven Bozinovski, Hao Wang, Nicholas J. Wilson, Ross Vlahos, Angelica Papanicolaou
Publikováno v:
British Journal of Pharmacology. 178:1869-1885
Background and purpose Asthma is a chronic disease that displays heterogeneous clinical and molecular features. A phenotypic subset of late-onset severe asthmatics has debilitating fixed airflow obstruction, increased neutrophilic inflammation and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e2b57b29a4e40e509cbc25dba921e5
https://doi.org/10.1111/bph.15415
https://doi.org/10.1111/bph.15415
Autor:
Jason C. Lao, Christine B. Bui, Merrin A. Pang, Steven X. Cho, Ina Rudloff, Kirstin Elgass, Jan Schröder, Anton Maksimenko, Niamh E. Mangan, Malcolm R. Starkey, Elisabeth M. Skuza, Yu B. Y. Sun, Friederike Beker, Clare L. Collins, Omar F. Kamlin, Kai König, Atul Malhotra, Kenneth Tan, Christiane Theda, Morag J. Young, Catriona A. McLean, Nicholas J. Wilson, Arvind Sehgal, Philip M. Hansbro, James T. Pearson, Jose M. Polo, Alex Veldman, Philip J. Berger, Claudia A. Nold-Petry, Marcel F. Nold
Publikováno v:
Science translational medicine. 14(639)
Postnatal maturation of the immune system is poorly understood, as is its impact on illnesses afflicting term or preterm infants, such as bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension. These are both cardiopulmonary infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2e2b4753e51cdfc85af03052509013
https://pubmed.ncbi.nlm.nih.gov/35385341
https://pubmed.ncbi.nlm.nih.gov/35385341
Autor:
Shenna Y. Langenbach, Jade Jaffar, Peter Vee Sin Lee, Ingrid Lönnstedt, Milica Ng, Asres Berhan, Glen P. Westall, Alastair G. Stewart, Monther Alhamdoosh, Nicholas J. Wilson, Trudi Harris, Michael J. Wilson, Fernando Jativa
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 63:819-830
Pathological changes in the biomechanical environment are implicated in the progression of idiopathic pulmonary fibrosis (IPF). Stiffened matrix augments fibroblast proliferation and differentiation and activates TGF-β1 (transforming growth factor-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e088fac3eec4debfae1483983a76cf34
https://doi.org/10.1165/rcmb.2020-0227oc
https://doi.org/10.1165/rcmb.2020-0227oc
Publikováno v:
Australian Journal of Psychology. 72:211-222
The aims of the present study are to investigate (a) whether a control task (i.e., the grocery imagery task) classically used in emotion research and designed to emulate emotional neutrality is tru...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b69a5e9e041ebe12d9f99694ce0fff
https://doi.org/10.1111/ajpy.12268
https://doi.org/10.1111/ajpy.12268