Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Nicholas J Tobias"'
Autor:
Sacha J Pidot, Stephan Klatt, Louis S Ates, Wafa Frigui, Fadel Sayes, Laleh Majlessi, Hiroshi Izumi, Ian R Monk, Jessica L Porter, Vicki Bennett-Wood, Torsten Seemann, Ashley Otter, George Taiaroa, Gregory M Cook, Nicholas West, Nicholas J Tobias, John A Fuerst, Michael D Stutz, Marc Pellegrini, Malcolm McConville, Roland Brosch, Timothy P Stinear
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012440 (2024)
Reconstructing the evolutionary origins of Mycobacterium tuberculosis, the causative agent of human tuberculosis, has helped identify bacterial factors that have led to the tubercle bacillus becoming such a formidable human pathogen. Here we report t
Externí odkaz:
https://doaj.org/article/c05a679dcd724c87b14f99cec3647995
Autor:
Anthony S Ablordey, Koen Vandelannoote, Isaac A Frimpong, Evans K Ahortor, Nana Ama Amissah, Miriam Eddyani, Lies Durnez, Françoise Portaels, Bouke C de Jong, Herwig Leirs, Jessica L Porter, Kirstie M Mangas, Margaret M C Lam, Andrew Buultjens, Torsten Seemann, Nicholas J Tobias, Timothy P Stinear
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003798 (2015)
Externí odkaz:
https://doaj.org/article/33c8b2f64bb54617b9a596a3cd65e8b9
Autor:
Anthony S Ablordey, Koen Vandelannoote, Isaac A Frimpong, Evans K Ahortor, Nana Ama Amissah, Miriam Eddyani, Lies Durnez, Françoise Portaels, Bouke C de Jong, Herwig Leirs, Jessica L Porter, Kirstie M Mangas, Margaret M C Lam, Andrew Buultjens, Torsten Seemann, Nicholas J Tobias, Timothy P Stinear
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003681 (2015)
Efforts to control the spread of Buruli ulcer--an emerging ulcerative skin infection caused by Mycobacterium ulcerans--have been hampered by our poor understanding of reservoirs and transmission. To help address this issue, we compared whole genomes
Externí odkaz:
https://doaj.org/article/4c95674c2da543cdb1a715be9207e340
Autor:
Nana Ama Amissah, Sophie Gryseels, Nicholas J Tobias, Bahram Ravadgar, Mitsuko Suzuki, Koen Vandelannoote, Lies Durnez, Herwig Leirs, Timothy P Stinear, Françoise Portaels, Anthony Ablordey, Miriam Eddyani
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3148 (2014)
The reservoir and mode of transmission of Mycobacterium ulcerans, the causative agent of Buruli ulcer, still remain a mystery. It has been suggested that M. ulcerans persists with difficulty as a free-living organism due to its natural fragility and
Externí odkaz:
https://doaj.org/article/8640b1c9efdc48e3934b0c9b6906af41
Autor:
Jessica L Porter, Nicholas J Tobias, Sacha J Pidot, Steffen Falgner, Kellie L Tuck, Andrea Vettiger, Hui Hong, Peter F Leadlay, Timothy P Stinear
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70520 (2013)
Mycolactones are polyketide-derived lipid virulence factors made by the slow-growing human pathogen, Mycobacterium ulcerans. Three unusually large and homologous plasmid-borne genes (mlsA1: 51 kb, mlsB: 42 kb and mlsA2: 7 kb) encode the mycolactone t
Externí odkaz:
https://doaj.org/article/f4488c8b8faa4147bb82d834045ccc60
Autor:
Nicholas J Tobias, Torsten Seemann, Sacha J Pidot, Jessica L Porter, Laurent Marsollier, Estelle Marion, Franck Letournel, Tasnim Zakir, Joseph Azuolas, John R Wallace, Hui Hong, John K Davies, Benjamin P Howden, Paul D R Johnson, Grant A Jenkin, Timothy P Stinear
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 3, Iss 11, p e553 (2009)
Mycolactone A/B is a lipophilic macrocyclic polyketide that is the primary virulence factor produced by Mycobacterium ulcerans, a human pathogen and the causative agent of Buruli ulcer. In M. ulcerans strain Agy99 the mycolactone polyketide synthase
Externí odkaz:
https://doaj.org/article/f5ca91bc94794b68aef17ebbecdb2553
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3051-3057 (2021)
Trypanosoma cruzi, the causative agent of Chagas disease (American trypanosomiasis), colonizes the intestinal tract of triatomines. Triatomine bugs act as vectors in the life cycle of the parasite and transmit infective parasite stages to animals and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4454da01e2e4ab225cd79f306de61231
https://doi.org/10.1016/j.csbj.2021.05.027
https://doi.org/10.1016/j.csbj.2021.05.027
Autor:
Yi-Ming Shi, Merle Hirschmann, Yan-Ni Shi, Shabbir Ahmed, Desalegne Abebew, Nicholas J. Tobias, Peter Grün, Jan J. Crames, Laura Pöschel, Wolfgang Kuttenlochner, Christian Richter, Jennifer Herrmann, Rolf Müller, Aunchalee Thanwisai, Sacha J. Pidot, Timothy P. Stinear, Michael Groll, Yonggyun Kim, Helge B. Bode
Publikováno v:
Nature Chemistry
Nat Chem
Nat Chem
Microorganisms contribute to the biology and physiology of eukaryotic hosts and affect other organisms through natural products. Xenorhabdus and Photorhabdus (XP) living in mutualistic symbiosis with entomopathogenic nematodes generate natural produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ebd9cea9fd140424a73059eec83e36
Autor:
Sophie Brameyer, Helge B. Bode, Nicholas J. Tobias, Darko Kresovic, Ralf Heermann, Jannis Brehm
Publikováno v:
Chembiochem
Quorum sensing (QS) is widely accepted as a procedure that bacteria use to converse. However, prevailing thinking places acyl homoserine lactones (AHLs) at the forefront of this communication pathway in Gram‐negative bacteria. With the advent of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40540c80b2576aa66aebc58876a684b2
https://doi.org/10.1002/cbic.201900580
https://doi.org/10.1002/cbic.201900580
Publikováno v:
Microbiome. 10(1)
The causative agent of Chagas disease, Trypanosoma cruzi, and its nonpathogenic relative, Trypanosoma rangeli, are transmitted by haematophagous triatomines and undergo a crucial ontogenetic phase in the insect's intestine. In the process, the parasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76fcf2eccea85b2b4f0810f6625b199e
https://pubmed.ncbi.nlm.nih.gov/35272716
https://pubmed.ncbi.nlm.nih.gov/35272716