Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicholas J Lodato"'
Publikováno v:
Toxicol Sci
Constitutive androstane receptor (CAR) (Nr1i3), a liver nuclear receptor and xenobiotic sensor, induces drug, steroid, and lipid metabolism and dysregulates genes linked to hepatocellular carcinogenesis, but its impact on the liver epigenome is poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4498b7712743c98fa1a531c963689f9
https://doi.org/10.1093/toxsci/kfz148
https://doi.org/10.1093/toxsci/kfz148
Publikováno v:
Toxicological Sciences. 164:115-128
Activation of the nuclear receptor and transcription factor CAR (Nr1i3) by its specific agonist ligand TCPOBOP (1, 4-bis[2-(3, 5-dichloropyridyloxy)]benzene) dysregulates hundreds of genes in mouse liver and is linked to male-biased hepatocarcinogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c77140dd4e0f1b6c5bbd845ff281eab
https://doi.org/10.1093/toxsci/kfy070
https://doi.org/10.1093/toxsci/kfy070
Publikováno v:
Toxicological Sciences. 159:25-41
Xenobiotic agonists of constitutive androstane receptor (CAR) induce many hepatic drug metabolizing enzymes, but following prolonged exposure, promote hepatocellular carcinoma, most notably in male mouse liver. Here, we used nuclear RNA-seq to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f587deb0fabe20ddac90646d15ff11a
https://doi.org/10.1093/toxsci/kfx114
https://doi.org/10.1093/toxsci/kfx114
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::912c1f1becd178e9ff4deae8fe446cf2
https://doi.org/10.1096/fasebj.29.1_supplement.lb515
https://doi.org/10.1096/fasebj.29.1_supplement.lb515
Autor:
Nicholas J Lodato, Kerri Stanley Yip, Jeannette Connerney, David J. Waxman, Alexander Suvorov
Publikováno v:
Biology of Reproduction. 89
Changes in the CD-1 mouse uterine transcriptome during proestrus and estrus were investigated to help elucidate mechanisms of uterine tissue remodeling during the estrus cycle and their regulation by estrogen and progesterone in preparation of the ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb2838438e581f081f883bdb2dd8a5d
https://doi.org/10.1095/biolreprod.112.107334
https://doi.org/10.1095/biolreprod.112.107334
Autor:
Kerri Stanley, Yip, Alexander, Suvorov, Jeannette, Connerney, Nicholas J, Lodato, David J, Waxman
Publikováno v:
Biology of reproduction. 89(1)
Changes in the CD-1 mouse uterine transcriptome during proestrus and estrus were investigated to help elucidate mechanisms of uterine tissue remodeling during the estrus cycle and their regulation by estrogen and progesterone in preparation of the ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccb220e27543034cbb7872f850402d56
https://pubmed.ncbi.nlm.nih.gov/23740946
https://pubmed.ncbi.nlm.nih.gov/23740946
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f754ca258b48a7e7b701d5fdad800065
https://doi.org/10.1096/fasebj.27.1_supplement.lb628
https://doi.org/10.1096/fasebj.27.1_supplement.lb628