Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Nicholas J DeVito"'
Autor:
Ben Goldacre, Carl Heneghan, Henry Drysdale, Nicholas J DeVito, Jessica Morley, James Andrew Smith
Publikováno v:
BMJ Medicine, Vol 3, Iss 1 (2024)
Objective To identify the availability of results for trials registered on the European Union Clinical Trials Register (EUCTR) compared with other dissemination routes to understand its value as a results repository.Design Cross sectional audit study
Externí odkaz:
https://doaj.org/article/614b54dd1d6e4757b4d49a96e1a9117f
Autor:
Ben Goldacre, David Evans, Sam Harper, Orla Macdonald, Alex J Walker, Richard Croker, William J Hulme, Colm D Andrews, Laurie A Tomlinson, Krishnan Bhaskaran, Henry Drysdale, Nicholas J DeVito, Ian J Douglas, Caroline E Morton, Jessica Morley, Bang Zheng, Brian MacKenna, Stephen J W Evans, Christopher T Rentsch, Helen J Curtis, Amir Mehrkar, Peter Inglesby, Jonathan Cockburn, John Parry, Frank Hester, Rose Higgins, Simon Davy, John Tazare, Viyaasan Mahalingasivam, George Hickman, Tom Ward, Rebecca M Smith, Amelia C A Green, Louis Fisher, Sebastian C J Bacon, Robin Y Park, Jon Massey, Iain Dillingham, Linda Nab, Christopher Bates, Lisa E M Hopcroft, Milan Wiedemann
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To ascertain patient eligibility status and describe coverage of antiviral drugs and neutralising monoclonal antibodies (nMAB) as treatment for covid-19 in community settings in England.Design Retrospective, descriptive cohort study, approv
Externí odkaz:
https://doaj.org/article/a60fb92626de4ac3ad60f635c2d29cc2
Autor:
Anna Schultze, Emily Nightingale, David Evans, William Hulme, Alicia Rosello, Chris Bates, Jonathan Cockburn, Brian MacKenna, Helen J Curtis, Caroline E Morton, Richard Croker, Seb Bacon, Helen I McDonald, Christopher T Rentsch, Krishnan Bhaskaran, Rohini Mathur, Laurie A Tomlinson, Elizabeth J Williamson, Harriet Forbes, John Tazare, Daniel Grint, Alex J Walker, Peter Inglesby, Nicholas J DeVito, Amir Mehrkar, George Hickman, Simon Davy, Tom Ward, Louis Fisher, Amelia CA Green, Kevin Wing, Angel YS Wong, Robert McManus, John Parry, Frank Hester, Sam Harper, Stephen JW Evans, Ian J Douglas, Liam Smeeth, Rosalind M Eggo, Ben Goldacre, David A Leon
Publikováno v:
The Lancet Regional Health. Europe, Vol 14, Iss , Pp 100295- (2022)
Summary: Background: Residents in care homes have been severely impacted by COVID-19. We describe trends in the mortality risk among residents of care homes compared to private homes. Methods: On behalf of NHS England we used OpenSAFELY-TPP to calcul
Externí odkaz:
https://doaj.org/article/55769e958fc4475a8f7850faac34e4b5
Publikováno v:
BJGP Open, Vol 6, Iss 1 (2022)
Background: The global burden of cardiovascular disease (CVD) is forecast to increase, and anticoagulants will remain important medicines for its management. Coroners' Prevention of Future Death reports (PFDs) provide valuable insights that may enabl
Externí odkaz:
https://doaj.org/article/6cd0b3cdfba644d4b2a27e4a6efc8f2e
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Objective To examine how and when the results of COVID-19 clinical trials are disseminated.Design Cross-sectional study.Setting The COVID-19 clinical trial landscape.Participants 285 registered interventional clinical trials for the treatment and pre
Externí odkaz:
https://doaj.org/article/03364a196c774cf3972184ba9bbd4cdc
Autor:
Anna Schultze, Chris Bates, Jonathan Cockburn, Brian MacKenna, Emily Nightingale, Helen J Curtis, William J Hulme, Caroline E Morton, Richard Croker, Seb Bacon, Helen I McDonald, Christopher T Rentsch, Krishnan Bhaskaran, Rohini Mathur, Laurie A Tomlinson, Elizabeth J Williamson, Harriet Forbes, John Tazare, Daniel J Grint, Alex J Walker, Peter Inglesby, Nicholas J DeVito, Amir Mehrkar, George Hickman, Simon Davy, Tom Ward, Louis Fisher, David Evans, Kevin Wing, Angel YS Wong, Robert McManus, John Parry, Frank Hester, Sam Harper, Stephen JW Evans, Ian J Douglas, Liam Smeeth, Rosalind M Eggo, Ben Goldacre
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Care home residents have been severely affected by the COVID-19 pandemic. Electronic Health Records (EHR) hold significant potential for studying the healthcare needs of this vulnerable population; however, identifying care home residents
Externí odkaz:
https://doaj.org/article/859325d2d5b04712a48a77ec027f86e2
Autor:
Nicholas J DeVito, Ben Goldacre
Publikováno v:
Clinical Trials. 19:172-183
Background/Aims: The European Union Clinical Trials Register is a public facing portal containing information on trials of medicinal products conducted under the purview of the European Union regulatory system. As of September 2021, the registry hold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce77af45a4a1e40b889981635676c36d
https://doi.org/10.1177/17407745211073483
https://doi.org/10.1177/17407745211073483
Publikováno v:
Journal of Clinical Epidemiology. 142:161-170
OBJECTIVE: To describe the trial results reporting behaviour of leading European non-commercial sponsors by country and over time. STUDY DESIGN AND SETTING: Cross-sectional analysis describing results reporting rates to the European Clinical Trials R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9d265b8d49e4db69c7747231905cce9
https://doi.org/10.1016/j.jclinepi.2021.11.005
https://doi.org/10.1016/j.jclinepi.2021.11.005
Autor:
Till Bruckner, Samruddhi Yerunkar, Okan Basegmez, Ronak Borana, Belén Chavarría, Mayra Velarde, Nicholas J. DeVito
Non-publication, incomplete publication and excessively slow publication of clinical trial outcomes contribute to research waste and can harm patients. In this cohort study, we used publicClinicalTrials.govregistry records to identify 81 paediatric c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117bd5ae281b7e5f4dcb70550c2b9da5
https://doi.org/10.1101/2023.01.17.23284683
https://doi.org/10.1101/2023.01.17.23284683
Autor:
Daniel Grint, Stephen J. W. Evans, Kevin Wing, John Parry, David M. Evans, Emily Nightingale, Ben Goldacre, John Tazare, Christopher M. Bates, Elizabeth Williamson, Frank Hester, Hamish Gibbs, Christopher T Rentsch, Simon Davy, Alex J Walker, Nicholas J DeVito, Anna Schultze, George Hickman, Amir Mehrkar, Helen Mcdonald, Sam Harper, Ian J. Douglas, Krishnan Bhaskaran, Richard Croker, Rohini Mathur, Catherine F Houlihan, Angel Y S Wong, Liam Smeeth, Caroline E Morton, Laurie A. Tomlinson, William J Hulme, Rosalind M Eggo, Brian MacKenna, Sebastian Bacon, Helen J Curtis, Peter Ingelsby, Jonathan Cockburn
Publikováno v:
Clinical Infectious Diseases. 75:e1120-e1127
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha variant (B.1.1.7) is associated with higher transmissibility than wild-type virus, becoming the dominant variant in England by January 2021. We aimed to describe the se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8857b1bc9672f183a3dd744ebe2dd84
https://doi.org/10.1093/cid/ciab754
https://doi.org/10.1093/cid/ciab754