Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicholas J Buchkovich"'
Autor:
Rinki Kumar, Rebecca Kaddis Maldonado, Neil D. Christensen, Maria C. Bewley, John M. Flanagan, Nicholas J. Buchkovich, Leslie J. Parent
Publikováno v:
COVID, Vol 4, Iss 9, Pp 1338-1354 (2024)
Human coronavirus 229E (HCoV-229E) is an alpha coronavirus that infects humans and bats. In common with all positive-strand RNA viruses, 229E infection causes rearrangements of the host’s intracellular membranes to form replication organelles, a hi
Externí odkaz:
https://doaj.org/article/dd85e27d05c04e1b820da13dff73191c
Autor:
Shaogeng Tang, Nicholas J Buchkovich, W Mike Henne, Sudeep Banjade, Yun Jung Kim, Scott D Emr
Publikováno v:
eLife, Vol 5 (2016)
The endosomal sorting complexes required for transport (ESCRT) pathway facilitates multiple fundamental membrane remodeling events. Previously, we determined X-ray crystal structures of ESCRT-III subunit Snf7, the yeast CHMP4 ortholog, in its active
Externí odkaz:
https://doaj.org/article/fe94cbe0e65e461bbec9cd9f7ae267c1
Autor:
Shaogeng Tang, W Mike Henne, Peter P Borbat, Nicholas J Buchkovich, Jack H Freed, Yuxin Mao, J Christopher Fromme, Scott D Emr
Publikováno v:
eLife, Vol 4 (2015)
The endosomal sorting complexes required for transport (ESCRTs) constitute hetero-oligomeric machines that catalyze multiple topologically similar membrane-remodeling processes. Although ESCRT-III subunits polymerize into spirals, how individual ESCR
Externí odkaz:
https://doaj.org/article/52954785127c44ecbee0802e0c51b073
Autor:
Rinki Kumar, Neil D. Christensen, Rebecca J. Kaddis Maldonado, Maria C. Bewley, Alexandria Ostman, Malgorzata Sudol, Eunice C. Chen, Natalie W. Buchkovich, Abhinay Gontu, Meera Surendran Nair, Ruth H. Nissly, Allen M. Minns, Vivek Kapur, Randall Rossi, Suresh V. Kuchipudi, Scott E. Lindner, Leslie J. Parent, John M. Flanagan, Nicholas J. Buchkovich
Publikováno v:
Viruses, Vol 13, Iss 10, p 1899 (2021)
Antibodies targeting the spike (S) and nucleocapsid (N) proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are essential tools. In addition to important roles in the treatment and diagnosis of infection, the availability of high
Externí odkaz:
https://doaj.org/article/ef8e0357932e405f88a0a1b6a9251f49
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) modulates numerous cellular pathways to facilitate infection. Iron is essential to many cellular processes and is often incorporated into proteins and enzymes involved in oxidative phosphorylation and DNA synthesis and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a2fb6b211333edbe598d9e96238358
https://europepmc.org/articles/PMC8941913/
https://europepmc.org/articles/PMC8941913/
Autor:
Vivek Kapur, Natalie W. Buchkovich, Neil D. Christensen, Nicholas J. Buchkovich, Alexandria Ostman, Eunice C. Chen, Ruth H. Nissly, John M. Flanagan, Malgorzata Sudol, Rebecca J. Kaddis Maldonado, Allen M. Minns, Scott E. Lindner, Abhinay Gontu, Leslie J. Parent, Suresh V. Kuchipudi, Maria C. Bewley, Rinki Kumar, Meera Surendran Nair, Randall M. Rossi
Publikováno v:
Viruses
Volume 13
Issue 10
Viruses, Vol 13, Iss 1899, p 1899 (2021)
Volume 13
Issue 10
Viruses, Vol 13, Iss 1899, p 1899 (2021)
Antibodies targeting the spike (S) and nucleocapsid (N) proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are essential tools. In addition to important roles in the treatment and diagnosis of infection, the availability of high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c826c3c9d61d3827e1e14afee7ed45a
Autor:
Xiaoming Liu, Thomas Abraham, Nicholas J. Buchkovich, Yoshinori Takahashi, Hong Gang Wang, Megan M. Young, Zhenyuan Tang, Han Chen, Xinwen Liang, Tatsuya Hattori, Haiyan He, Yuka Imamura-Kawasawa
Publikováno v:
The Journal of Cell Biology
Takahashi et al. perform a genome-wide CRISPR screen using the HaloTag-LC3 assay to gain insight into the mechanisms of phagophore closure. They identify a role for VPS37A in coordinating the ESCRT assembly on the phagophore for membrane closure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26c6b21af115e4a9e4befacb0c4cbe1
http://europepmc.org/articles/PMC6781443
http://europepmc.org/articles/PMC6781443
Autor:
Dhimant Desai, Ge Jin, Aron E. Lukacher, Alexandria Ostman, Linda Cruz, Nicholas J. Buchkovich, Matthew D. Lauver, Kevin Ferguson, Shantu Amin, Daniel Brosius, Brianne Roper
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1795-1803
Opportunistic viruses are a major problem for immunosuppressed individuals, particularly following organ or stem cell transplantation. Current treatments are non-existent or suffer from problems such as high toxicity or development of resistant strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fe6fb25863dc3d787cbbf7678763f7
https://doi.org/10.1016/j.bmc.2019.03.026
https://doi.org/10.1016/j.bmc.2019.03.026
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) manipulates cellular processes associated with secretory pathways within an infected cell to facilitate efficient viral replication. However, little is known about how HCMV infection alters the surrounding cellular enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1b457d57a97e3380fae9ea34d611e2
https://doi.org/10.1128/jvi.00609-20
https://doi.org/10.1128/jvi.00609-20
Publikováno v:
J Virol
Little is known about the human cytomegalovirus (HCMV) tegument protein UL88. Large-scale genomic studies have reported disparate results for UL88-null viruses, reporting both no phenotype and a >1-log decrease in virus titers. UL88 has also been rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f15ed99c16ec2c661605c6dcf0205f
https://pubmed.ncbi.nlm.nih.gov/32376624
https://pubmed.ncbi.nlm.nih.gov/32376624