Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nicholas J Anthis"'
Publikováno v:
PLoS Biology, Vol 6, Iss 9, p e240 (2008)
Externí odkaz:
https://doaj.org/article/a6aad1aa871d4959bc1a7aa2f0d36fe7
The Global Challenge to Prevent Breast Cancer: Surfacing New Ideas to Accelerate Prevention Research
Publikováno v:
International Journal of Environmental Research and Public Health, vol 17, iss 4
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 4, p 1394 (2020)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 4, p 1394 (2020)
Despite increases in screening and advances in treatment, breast cancer continues to be the most common cancer and cause of cancer deaths among women worldwide, and breast cancer rates have remained steady for decades. A new focus on population-level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eeff041ada69c1bf5621a44afbb36ca
https://doi.org/10.3390/ijerph17041394
https://doi.org/10.3390/ijerph17041394
Autor:
G. Marius Clore, Nicholas J. Anthis
Publikováno v:
Quarterly Reviews of Biophysics. 48:35-116
Myriad biological processes proceed through states that defy characterization by conventional atomic-resolution structural biological methods. The invisibility of these ‘dark’ states can arise from their transient nature, low equilibrium populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a2abcc9376964ffb6cf63657dd943e
https://doi.org/10.1017/s0033583514000122
https://doi.org/10.1017/s0033583514000122
Autor:
Nicholas J. Anthis, G. Marius Clore
Publikováno v:
Journal of the American Chemical Society. 135:9648-9651
Calmodulin (CaM), the prototypical calcium sensing protein in eukaryotes, comprises two domains separated by a short flexible linker, which allows CaM to assume a wide range of extended and compact conformations. Here we use NMR relaxation measuremen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18f09d585d8847faba67f8f223bf48a
https://doi.org/10.1021/ja4051422
https://doi.org/10.1021/ja4051422
Autor:
G. Marius Clore, Nicholas J. Anthis
Publikováno v:
Protein Science. 22:851-858
Quantitative studies in molecular and structural biology generally require accurate and precise determination of protein concentrations, preferably via a method that is both quick and straightforward to perform. The measurement of ultraviolet absorba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87113f4864488761ad0a9efedbcd6aac
https://doi.org/10.1002/pro.2253
https://doi.org/10.1002/pro.2253
Autor:
Iain D. Campbell, Nicholas J. Anthis
Integrins are essential adhesion receptors found on the surfaces of all metazoan cells. As regulators of cell migration and extracellular matrix assembly, these membrane-spanning heterodimers are critical for embryonic development, tissue repair and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64e39222ce7da71846ad44e511da69
https://ora.ox.ac.uk/objects/uuid:f6383bda-f578-47d0-a5d8-7867a383df78
https://ora.ox.ac.uk/objects/uuid:f6383bda-f578-47d0-a5d8-7867a383df78
Autor:
Nicolas L. Fawzi, Kálmán Hideg, Nicholas J. Anthis, Wayne L. Hubbell, Tamás Kálai, Mark R. Fleissner, G. Marius Clore
Publikováno v:
Journal of Biomolecular NMR. 51:105-114
The measurement of (1)H transverse paramagnetic relaxation enhancement (PRE) has been used in biomolecular systems to determine long-range distance restraints and to visualize sparsely-populated transient states. The intrinsic flexibility of most nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c731f002287f246903d0d406f7a1ca1f
https://doi.org/10.1007/s10858-011-9545-x
https://doi.org/10.1007/s10858-011-9545-x
Autor:
Mark S.P. Sansom, Iain D. Campbell, Benjamin T. Goult, Nicholas J. Anthis, Kate L. Wegener, Antreas C. Kalli
Publikováno v:
Structure(London, England:1993)
Summary Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20ae1186a471f7508ba02d585bd5745
Autor:
Feng Ye, Nicholas J. Anthis, Kate L. Wegener, Benjamin T. Goult, David R. Critchley, Edward D. Lowe, Ioannis Vakonakis, Iain D. Campbell, Mark H. Ginsberg, Neil Bate, Chungho Kim
Publikováno v:
The EMBO Journal. 28:3623-3632
Fundamental to cell adhesion and migration, integrins are large heterodimeric membrane proteins that uniquely mediate inside-out signal transduction, whereby adhesion to the extracellular matrix is activated from within the cell by direct binding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e0471255641b36d26b27edfeb2d71d
https://doi.org/10.1038/emboj.2009.287
https://doi.org/10.1038/emboj.2009.287
Autor:
Igor L. Barsukov, Mohamed Bouaouina, Iain D. Campbell, David A. Calderwood, David S. Harburger, Bipin Patel, Benjamin T. Goult, Nicholas J. Anthis, David R. Critchley, Gordon C. K. Roberts, Neil Bate
Publikováno v:
Journal of Molecular Biology
The integrin family of heterodimeric cell adhesion molecules exists in both low- and high-affinity states, and integrin activation requires binding of the talin FERM (four-point-one, ezrin, radixin, moesin) domain to membrane-proximal sequences in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fce53d437dc839fc4ad01967c84257c
http://europepmc.org/articles/PMC2963925
http://europepmc.org/articles/PMC2963925