Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Nicholas Hodge"'
Publikováno v:
Journal of Primary Care & Community Health, Vol 14 (2023)
Purpose: The new era of direct-acting antivirals (DAAs) against the hepatitis C virus (HCV) has led many primary care clinicians to begin treating HCV. Nevertheless, many patients are referred to specialists due to comorbidities, care complexities, a
Externí odkaz:
https://doaj.org/article/37326c95b01f4501ad5984982e5374a1
Autor:
Nikolai F. Sepetov, James D. Arroway, Olga Issakova, Dennis Lagasca, Ajit Jadhav, Min Chen, Ioana Popa-Burke, Paul Bernasconi, Scott Galasinski, Robert P. Mohney, Darren A. Sparkman, Roderic S. Lewis, Louis Coudurier, Darren Liu, William P. Janzen, C. Nicholas Hodge
Publikováno v:
Analytical Chemistry. 76:7278-7287
As part of an overall systems approach to generating highly accurate screening data across large numbers of compounds and biological targets, we have developed and implemented streamlined methods for purifying and quantitating compounds at various st
Publikováno v:
Catalysis Today. 72:107-113
We have identified two main mechanisms for inducing low-temperature activity in precious metal catalysts: normal-support activation (NSA) and active-phase enhancement (APE). The usual roles of a precious metal and its metal oxide support are reversed
Autor:
Stanislaw E. Golunski, Quentin A. Pankhurst, Mohammed Rafiq H. Siddiqui, Christopher J. Kiely, Robin Whyman, F. E. Wagner, Raj Rao Rajaram, Nicholas Hodge, Graham J. Hutchings
Publikováno v:
Catalysis Today. 72:133-144
A series of gold/iron-oxide catalysts has been prepared by an inverse co-precipitation method from a mixture of HAuCl4·3H2O and Fe(NO3)3·9H2O. Samples calcined at 400 °C for 3 h exhibited poor activity towards CO oxidation, whereas uncalcined mate
Autor:
Graham J. Hutchings, Jillian E. Bailie, Jian-Guo Zhang, Neville V. Richardson, Christopher J. Kiely, James A. Anderson, Halim A. Abdullah, Nicholas Hodge, A. Burrows, Colin H. Rochester
Publikováno v:
Physical Chemistry Chemical Physics. 3:4113-4121
The hydrogenation of but-2-enal over supported Au catalysts is discussed, together with a detailed characterisation study using X-ray diffraction, infrared spectroscopy and transmission electron microscopy. Au/ZnO catalysts are found to be selective
Autor:
Robin Whyman, F. E. Wagner, Graham J. Hutchings, M. Rafiq H. Siddiqui, Rowan M. Finch, Nicholas Hodge, Quentin A. Pankhurst, Adrian Meagher
Publikováno v:
Physical Chemistry Chemical Physics. 1:485-489
In the light of a recent study which identified the beneficial influence of poorly crystallised ferrihydrite Fe5HO8·4H2O on the activity of CO conversion catalysts comprising gold nanoparticles on oxidic iron, we have investigated three series of fe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:3615-3620
A new class of tricyclic ureas containing a conformationally constrained proline was designed with the aid of molecular modeling. Efficient stereoselective intermolecular pinacol coupling represented the highlight of the synthesis. These rigid cyclic
Publikováno v:
Tetrahedron Letters. 38:7951-7954
Trans-3-alkyl- or -arylcyclopropanecarboxylates, substituted in the 2-position with alkoxycarbonyl or nitrile groups, are efficiently prepared by coupling bromoacetic acid with Wang resin followed by pyridinium ylide formation and condensation of the
Autor:
C. Nicholas Hodge, Zelda R. Wasserman
Publikováno v:
Proteins: Structure, Function, and Genetics. 24:227-237
We used molecular dynamics computer simulation to "fly" a small flexible ligand, L-leucine hydroxamic acid, into the active site of thermolysin. The potential, which imposed no constraints between protein and ligand, produced conformations close to t
Publikováno v:
The Journal of Organic Chemistry. 61:2081-2084
A new procedure for cyclohexenone annelation has been developed. Thus, alkylation of 4-isopropylcyclohexanone with allyl bromide gives, over several steps, ketone 8. Exposure to (trimethylsilyl)diazomethane and MeLi smoothly cyclized 8 to the cyclope