Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicholas Heitman"'
Autor:
Amélie Rezza, Zichen Wang, Rachel Sennett, Wenlian Qiao, Dongmei Wang, Nicholas Heitman, Ka Wai Mok, Carlos Clavel, Rui Yi, Peter Zandstra, Avi Ma’ayan, Michael Rendl
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 3001-3018 (2016)
The hair follicle (HF) is a complex miniorgan that serves as an ideal model system to study stem cell (SC) interactions with the niche during growth and regeneration. Dermal papilla (DP) cells are required for SC activation during the adult hair cycl
Externí odkaz:
https://doaj.org/article/60c691e8f75c41b48a54c03bfd28fdc7
Autor:
Pieter Martino, Raghava Sunkara, Nicholas Heitman, Martina Rangl, Alexia Brown, Nivedita Saxena, Laura Grisanti, Donald Kohan, Masashi Yanagisawa, Michael Rendl
Publikováno v:
Nature Cell Biology.
Publikováno v:
Exp Dermatol
Hair follicles cyclically regenerate throughout adult mammalian life, owing to a resident population of epithelial hair follicle stem cells. Stem cell (SC) activity drives bouts of follicle growth, which are periodically interrupted by follicle regre
Publikováno v:
Current Opinion in Cell Biology. 55:87-95
Adult tissue-specific stem cells are essential for homeostatic tissue maintenance and key to regeneration during injury repair or disease. Many critical stem cell functions rely on the presence of well-timed cues from the microenvironment or niche, w
Autor:
Nicholas Heitman, Zichen Wang, Devika Srivastava, Pieter A Martino, Rachel Sennett, Avi Ma'ayan, Ka-Wai Mok, Laura Grisanti, Nivedita Saxena, Michael Rendl, Panteleimon Rompolas
Publikováno v:
Science
Niche relocated by muscle contraction Regulation of adult stem cells by their microenvironment, or niche, is essential for tissue homeostasis and for regeneration after injury and during aging. Normal regression of hair follicles during the hair cycl
Autor:
Avi Ma'ayan, Yutao Su, Zichen Wang, Nicholas Heitman, Lu M. Yang, Tina Jacob, Mauro J. Muraro, Rachel Sennett, Devika Srivastava, Ka-Wai Mok, Michael Rendl, David M. Ornitz, Laura Grisanti, Nivedita Saxena, Maria Kasper
Publikováno v:
SSRN Electronic Journal.
SUMMARYCell fate transitions are essential for specialization of stem cells and their niches, but the precise timing and sequence of molecular events during embryonic development are largely unknown. Here, we show that dermal condensates (DC), signal
Autor:
Nicholas Heitman, Lu M. Yang, Zichen Wang, Yutao Su, Maria Kasper, Rachel Sennett, Avi Ma'ayan, Mauro J. Muraro, Michael Rendl, David M. Ornitz, Ka-Wai Mok, Laura Grisanti, Nivedita Saxena, Tina Jacob, Devika Srivastava
Publikováno v:
Developmental Cell. 48:32-48.e5
Cell fate transitions are essential for specification of stem cells and their niches, but the precise timing and sequence of molecular events during embryonic development are largely unknown. Here, we identify, with 3D and 4D microscopy, unclustered
Autor:
Michael Rendl, Rachel Sennett, Zichen Wang, Avi Ma'ayan, Ka-Wai Mok, Amélie Rezza, Nicholas Heitman
Publikováno v:
Journal of Investigative Dermatology. 138:S235
Publikováno v:
Journal of bacteriology. 197(17)
In Salmonella enterica , the thiamine biosynthetic intermediate 5-aminoimidazole ribotide (AIR) can be synthesized de novo independently of the early purine biosynthetic reactions. This secondary route to AIR synthesis is dependent on (i) 5-amino-4-i
Autor:
Michael Rendl, Nicholas Heitman, Amélie Rezza, Carlos Clavel, Rachel Sennett, Zichen Wang, Cristina Sicchio, Avi Ma'ayan, Laura Grisanti, Nataly Roitershtein, Ka-Wai Mok
Publikováno v:
Developmental cell. 34(5)
SummaryDefining the unique molecular features of progenitors and their niche requires a genome-wide, whole-tissue approach with cellular resolution. Here, we co-isolate embryonic hair follicle (HF) placode and dermal condensate cells, precursors of a