Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nicholas Heeley"'
Autor:
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L. Evans, Florian T. Merkle, Frank Reimann, Fiona M. Gribble, Clemence Blouet
Publikováno v:
Molecular Metabolism, Vol 10, Iss , Pp 14-27 (2018)
Objective: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which hypothalamic neural cir
Externí odkaz:
https://doaj.org/article/ca276ba2670243aeb41eb1b77aef2f9a
Autor:
Luke K. Burke, Emmanuel Ogunnowo-Bada, Teodora Georgescu, Claudia Cristiano, Pablo B. Martinez de Morentin, Lourdes Valencia Torres, Giuseppe D'Agostino, Christine Riches, Nicholas Heeley, Yue Ruan, Marcelo Rubinstein, Malcolm J. Low, Martin G. Myers, Justin J. Rochford, Mark L. Evans, Lora K. Heisler
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1092-1102 (2017)
Objective: The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the mechanisms mediating glucose homeostasis to accelerate the identification of new medicat
Externí odkaz:
https://doaj.org/article/d5d57fc4ef3a41a08e876808e1d9eeec
Autor:
Brian Y.H. Lam, Irene Cimino, Joseph Polex-Wolf, Sara Nicole Kohnke, Debra Rimmington, Valentine Iyemere, Nicholas Heeley, Chiara Cossetti, Reiner Schulte, Luis R. Saraiva, Darren W. Logan, Clemence Blouet, Stephen O'Rahilly, Anthony P. Coll, Giles S.H. Yeo
Publikováno v:
Molecular Metabolism, Vol 6, Iss 5, Pp 383-392 (2017)
Objective: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture. Methods: Using single cell RNA sequencin
Externí odkaz:
https://doaj.org/article/420acb59b9a143a7bd33fe340d1f7af7
Autor:
Nicholas Heeley, Clemence Blouet
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Dietary protein quantity and quality greatly impact metabolic health via evolutionary-conserved mechanisms that ensure avoidance of amino acid imbalanced food sources, promote hyperphagia when dietary protein density is low, and conversely produce sa
Externí odkaz:
https://doaj.org/article/f898527c2bb249eb92e67dc97eb19f8c
Autor:
Ana P García, Teemu Aitta-aho, Laura Schaaf, Nicholas Heeley, Lena Heuschmid, Yunjing Bai, Francisco J Barrantes, John Apergis-Schoute
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133327 (2015)
Nicotinic acetylcholine receptors (nAChRs) play an important role in regulating appetite and have been shown to do so by influencing neural activity in the hypothalamus. To shed light on the hypothalamic circuits governing acetylcholine's (ACh) regul
Externí odkaz:
https://doaj.org/article/ca8e647490d542bcb5e598c473e973e4
Autor:
Fiona M. Gribble, Clemence Blouet, Mark L. Evans, Peter Kirwan, Frank Reimann, Marion Arnaud, Tamana Darwish, Florian T. Merkle, Nicholas Heeley
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 10, Iss, Pp 14-27 (2018)
Molecular Metabolism, Vol 10, Iss, Pp 14-27 (2018)
Objective Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which hypothalamic neural circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd87ee19a1d709e9c8c3f3d33765d73
Autor:
Luis R. Saraiva, Joseph Polex-Wolf, Stephen O'Rahilly, Anthony P. Coll, Chiara Cossetti, Reiner Schulte, Valentine P. Iyemere, Brian Y.H. Lam, Debra Rimmington, Sara Kohnke, Nicholas Heeley, Darren W. Logan, Irene Cimino, Giles S.H. Yeo, Clemence Blouet
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 5, Pp 383-392 (2017)
Molecular Metabolism, Vol 6, Iss 5, Pp 383-392 (2017)
Objective Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture. Methods Using single cell RNA sequencing,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ed89391711fba13ab8089572265820
https://www.repository.cam.ac.uk/handle/1810/264134
https://www.repository.cam.ac.uk/handle/1810/264134
Autor:
Clemence Blouet, Nicholas Heeley
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Frontiers in Endocrinology
Frontiers in Endocrinology
Dietary protein quantity and quality greatly impact metabolic health via evolutionary-conserved mechanisms that ensure avoidance of amino acid imbalanced food sources, promote hyperphagia when dietary protein density is low, and conversely produce sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab88a213b974d656c3b61c456e46c91
https://www.repository.cam.ac.uk/handle/1810/275621
https://www.repository.cam.ac.uk/handle/1810/275621
Autor:
Yunjing Bai, Laura Schaaf, Teemu Aitta-aho, Lena Heuschmid, Francisco J. Barrantes, Ana Paula Garcia, Nicholas Heeley, John Apergis-Schoute
Publikováno v:
PLoS ONE Vol. 10, N° 8, 2015
PLoS ONE, Vol 10, Iss 8, p e0133327 (2015)
PLoS ONE
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
PLoS ONE, Vol 10, Iss 8, p e0133327 (2015)
PLoS ONE
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
Fil: Garcia, Ana P. University of Cambridge. Department of Pharmacology; Reino Unido Fil: García, Ana P. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Neurobiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cbb5c48070162991259c73ae1683cd
https://repositorio.uca.edu.ar/handle/123456789/8735
https://repositorio.uca.edu.ar/handle/123456789/8735