Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nicholas Grayson"'
Autor:
Sreejith Jayasree Varma, Enrica Calvani, Nana-Maria Grüning, Christoph B Messner, Nicholas Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser
Publikováno v:
eLife, Vol 11 (2022)
Interpreting the function and metabolism of enzymatic DNA modifications requires both position-specific and global quantities. Sequencing-based techniques that deliver the former have become broadly accessible, but analytical methods for the global q
Externí odkaz:
https://doaj.org/article/cdb0f9a3469c422abcd659712ef826e1
Autor:
Jane R. Millar, Nomonde Bengu, Rowena Fillis, Ken Sprenger, Vuyokazi Ntlantsana, Vinicius A. Vieira, Nisreen Khambati, Moherndran Archary, Maximilian Muenchhoff, Andreas Groll, Nicholas Grayson, John Adamson, Katya Govender, Krista Dong, Photini Kiepiela, Bruce D. Walker, David Bonsall, Thomas Connor, Matthew J. Bull, Nelisiwe Nxele, Julia Roider, Nasreen Ismail, Emily Adland, Maria C. Puertas, Javier Martinez-Picado, Philippa C. Matthews, Thumbi Ndung'u, Philip Goulder
Publikováno v:
EClinicalMedicine, Vol 22, Iss , Pp - (2020)
Background: Early combination antiretroviral therapy (cART) reduces the size of the viral reservoir in paediatric and adult HIV infection. Very early-treated children may have higher cure/remission potential. Methods: In an observational study of 151
Externí odkaz:
https://doaj.org/article/61a2b26377714f00b5db58796befa090
Autor:
Enrica Calvani, Sreejith Jayasree Varma, Nana-Maria Grüning, Christoph B Messner, Nicholas Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser
Funder: Medical Research Council
Interpreting the function and metabolism of enzymatic DNA modifications requires both position-specific and global quantities. Sequencing-based techniques that deliver the former have become broadly accessible, b
Interpreting the function and metabolism of enzymatic DNA modifications requires both position-specific and global quantities. Sequencing-based techniques that deliver the former have become broadly accessible, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e22512e7db58a7069a63a9504341e0b
Autor:
Enrica Calvani, Sreejith Jayasree Varma, Nana-Maria Grüning, Christoph B Messner, Nicholas Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5bc15b9a2551659aa9386761496cd9a
https://doi.org/10.7554/elife.81002.sa2
https://doi.org/10.7554/elife.81002.sa2
Autor:
Sreejith Jayasree Varma, Enrica Calvani, Nana-Maria Grüning, Christoph Messner, Nicholas Grayson, Floriana Capuano, Michael Mülleder, Markus Ralser
Enzymatic DNA modifications like methylcytosine (5mdC), methyladenine (N6mdA), or hydroxymethylcytosine (5hmdC) are key for chromatin function, gene expression regulation, and antiviral defense, but they remain understudied in non-model organisms. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36a8b281698dcc1658ce373e3eb8ed0
https://doi.org/10.1101/2022.03.22.485282
https://doi.org/10.1101/2022.03.22.485282
Autor:
Reena R. D’Souza, David Bonsall, Philip J. R. Goulder, Vinicius A Vieira, Maximilian Muenchhoff, Cherrelle Dacon, Emily Adland, Anna Csala, Fa’eeda Richards, Pieter Jooste, Nicholas Grayson, M. H. Tsai, Rohin Athavale
Publikováno v:
Journal of virology. 96(2)
HIV-specific CD8+ T-cells play a central role in immune control of adult HIV, but their contribution in paediatric infection is less well-characterised. Previously, we identified a group of ART-naive children with persistently undetectable plasma vir
SECOND GENERATION MOTHER-TO-CHILD HIV TRANSMISSION IN SOUTH AFRICA IS CHARACTERISED BY POOR OUTCOMES
Autor:
Jane Millar, Nomonde Bengu, Noxolo Mchunu, Thumbi Ndung'u, Philip J. R. Goulder, Moherndran Archary, Isabella Fatti, David Bonsall, Nicholas Grayson, Emily Adland, Philippa C Matthews
Publikováno v:
AIDS
Objective The worldwide incidence of pregnancy for women living with perinatal HIV infection is increasing. Subsequently, there is growing risk of second-generation mother-to-child HIV transmission. The infant clinical outcomes for such a phenomenon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536cce13f68759e3267e9a458e7215b5
https://europepmc.org/articles/PMC8288499/
https://europepmc.org/articles/PMC8288499/
Autor:
Maria Zambon, Tim Brooks, Robin Gopal, Matthew Robb, Steven Dicks, Monika Patel, Abbie Bown, Sunetra Gupta, Jai S Bolton, Alex Fyfe, Nicholas Grayson, Juthathip Mongkolsapaya, David J. Roberts, Gail Miflin, Daniel Bailey, Dejnirattisai Wanwisa, Heli Harvala, Richard Vipond, Craig Thompson, Rutger J. Ploeg, Gavin R. Screaton, Nicholas A. Watkins, Piyada Supasa, Chang Liu, Nigel J. Temperton, Peter Simmonds, Samreen Ijaz
Publikováno v:
Transfusion Medicine
Introduction: The lack of approved specific therapeutic agents to treat coronavirus disease (COVID‐19) associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has led to the rapid implementation of convalescent pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8c375459cc21caeedd4d4d755ccba6
https://doi.org/10.1111/tme.12746
https://doi.org/10.1111/tme.12746
Autor:
M Pace, Sarah Fidler, Lucia Parolini, John Frater, Matthew Jones, Ane Ogbe, P Goulder, Pontiano Kaleebu, Nicola Robinson, Harriet R. Brown, Emanuele Marchi, Zacharapoulou P, Paul Klenerman, Nicholas Grayson, Helen Rees
Although certain individuals with HIV infection can stop antiretroviral therapy (ART) without evidence of viral load rebound, the mechanisms under-pinning ‘post-treatment control’ remain unclear. Twelve individuals who had received 12 months of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cd177e1b965ec967dfe47758f0836ac
https://doi.org/10.1101/2020.11.24.395574
https://doi.org/10.1101/2020.11.24.395574
Autor:
Andreas Groll, Philippa C Matthews, Ken Sprenger, Nelisiwe Nxele, Bruce D. Walker, Nicholas Grayson, Photini Kiepiela, Julia Roider, Emily Adland, Krista L. Dong, Maria C. Puertas, Nisreen Khambati, Nomonde Bengu, Matthew J. Bull, David Bonsall, Thomas R. Connor, Katya Govender, Jane Millar, Rowena Fillis, John W. Adamson, Moherndran Archary, Vinicius A Vieira, Philip J. R. Goulder, Maximilian Muenchhoff, Nasreen Ismail, Thumbi Ndung'u, Vuyokazi Ntlantsana, Javier Martinez-Picado
Publikováno v:
EClinicalMedicine, Vol 22, Iss, Pp-(2020)
EClinicalMedicine
EClinicalMedicine
Background: Early combination antiretroviral therapy (cART) reduces the size of the viral reservoir in paediatric and adult HIV infection. Very early-treated children may have higher cure/remission potential. Methods: In an observational study of 151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d027f58ec77df9fc0ed584c0cb038c
https://ora.ox.ac.uk/objects/uuid:112d96f6-9c6c-4237-8e88-de8c60ac261a
https://ora.ox.ac.uk/objects/uuid:112d96f6-9c6c-4237-8e88-de8c60ac261a