Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicholas Gaston"'
Autor:
Nathan Bamidele, Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig, Hanbing Cao, Karen Kelly, Jonathan K. Watts, Jun Xie, Guangping Gao, Erik J. Sontheimer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nme2Cas9 has been established as a genome editing platform with compact size, high accuracy, and broad targeting range, including single-AAV-deliverable adenine base editors. Here, we engineer Nme2Cas9 to further increase the activity and ta
Externí odkaz:
https://doaj.org/article/df3d02ad296b4505893c699918456904
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Targeted insertion of large DNA fragments holds promise for genome engineering and gene therapy. Prime editing (PE) effectively inserts short (400 bp) remains low and in vivo application has not been demonstrated. Inspired by the efficient g
Externí odkaz:
https://doaj.org/article/198f86c79bc94a7cb8636247cdf4344c
Autor:
Nathan Bamidele, Han Zhang, Xiaolong Dong, Nicholas Gaston, Haoyang Cheng, Karen Kelly, Jonathan K. Watts, Jun Xie, Guangping Gao, Erik J. Sontheimer
Publikováno v:
bioRxiv
Nme2Cas9 has been established as a genome editing platform with compact size, high accuracy, and broad targeting range, including single-AAV-deliverable adenine base editors. Here, we have engineered Nme2Cas9 to further increase the activity and targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9221d20e5f7922c51fa056171d4094a
https://europepmc.org/articles/PMC10153126/
https://europepmc.org/articles/PMC10153126/
Autor:
Han Zhang, Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala, Zexiang Chen, Nicholas Gaston, Gregory A. Newby, Jun Xie, David R. Liu, Guangping Gao, Scot A. Wolfe, Anastasia Khvorova, Jonathan K. Watts, Erik J. Sontheimer
Publikováno v:
bioRxiv
Guide RNAs offer programmability for CRISPR-Cas9 genome editing but also add challenges for delivery. Chemical modification, which has been key to the success of oligonucleotide therapeutics, can enhance the stability, distribution, cellular uptake,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1df83c3abdb4daf8faae6772edac4e7
https://europepmc.org/articles/PMC10055305/
https://europepmc.org/articles/PMC10055305/
Publikováno v:
Volume 7: Engineering Education and Professional Development.
For our Junior Project course we worked with John Anderson, apart of the Mechanical and Manufacturing Engineering and Technology department at Oregon Institute of Technology, to build a Robotic Control System. This system would allow a more cost effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2749857f531493a7f490a82b108cc5d
https://doi.org/10.1115/imece2007-43183
https://doi.org/10.1115/imece2007-43183