RIPOSTE: a framework for improving the design and analysis of laboratory-based research

Autor: Nicholas GD Masca, Elizabeth MA Hensor, Victoria R Cornelius, Francesca M Buffa, Helen M Marriott, James M Eales, Michael P Messenger, Amy E Anderson, Chris Boot, Catey Bunce, Robert D Goldin, Jessica Harris, Rod F Hinchliffe, Hiba Junaid, Shaun Kingston, Carmen Martin-Ruiz, Christopher P Nelson, Janet Peacock, Paul T Seed, Bethany Shinkins, Karl J Staples, Jamie Toombs, Adam KA Wright, M Dawn Teare

Publikováno v: eLife, Vol 4 (2015)

Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contr

Externí odkaz: https://doaj.org/article/a0d7e699f1c042edb9b4707dd4859347

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Autor: Turcot, Valérie, Lu, Yingchang, Highland, Heather M, Schurmann, Claudia, Justice, Anne E, Fine, Rebecca S, Bradfield, Jonathan P, Esko, Tõnu, Giri, Ayush, Graff, Mariaelisa, Guo, Xiuqing, Hendricks, Audrey E, Karaderi, Tugce, Lempradl, Adelheid, Locke, Adam E, Mahajan, Anubha, Marouli, Eirini, Sivapalaratnam, Suthesh, Young, Kristin L, Alfred, Tamuno, Feitosa, Mary F, Masca, Nicholas GD, Manning, Alisa K, Medina-Gomez, Carolina, Mudgal, Poorva, Ng, Maggie CY, Reiner, Alex P, Vedantam, Sailaja, Willems, Sara M, Winkler, Thomas W, Abecasis, Gonçalo, Aben, Katja K, Alam, Dewan S, Alharthi, Sameer E, Allison, Matthew, Amouyel, Philippe, Asselbergs, Folkert W, Auer, Paul L, Balkau, Beverley, Bang, Lia E, Barroso, Inês, Bastarache, Lisa, Benn, Marianne, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bots, Michiel L, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Breen, Gerome, Brilliant, Murray H, Broer, Linda, Brumat, Marco, Burt, Amber A, Butterworth, Adam S, Campbell, Peter T, Cappellani, Stefania, Carey, David J, Catamo, Eulalia, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der I, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cocca, Massimiliano, Collins, Francis S, Cook, James P, Corley, Janie, Corominas Galbany, Jordi, Cox, Amanda J, Crosslin, David S, Cuellar-Partida, Gabriel, D'Eustacchio, Angela, Danesh, John, Davies, Gail, Bakker, Paul IW, Groot, Mark CH, Mutsert, Renée, Deary, Ian J, Dedoussis, George, Demerath, Ellen W, Heijer, Martin, Hollander, Anneke I, Ruijter, Hester M, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Drenos, Fotios, Du, Mengmeng, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F

Publikováno v: Nature genetics, vol 50, iss 1

Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from which pinpointing causal genes remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d1520bad5fa2b8df56900ebfc27500a0
https://escholarship.org/uc/item/2j05q4qq

Rare and low-frequency coding variants alter human adult height

Autor: Marouli, Eirini, Graff, Mariaelisa, Medina-Gomez, Carolina, Lo, Ken Sin, Wood, Andrew R, Kjaer, Troels R, Fine, Rebecca S, Lu, Yingchang, Schurmann, Claudia, Highland, Heather M, Rueger, Sina, Thorleifsson, Gudmar, Justice, Anne E, Lamparter, David, Stirrups, Kathleen E, Turcot, Valerie, Young, Kristin L, Winkler, Thomas W, Esko, Tonu, Karaderi, Tugce, Locke, Adam E, Masca, Nicholas GD, Ng, Maggie CY, Mudgal, Poorva, Rivas, Manuel A, Vedantam, Sailaja, Mahajan, Anubha, Guo, Xiuqing, Abecasis, Goncalo, Aben, Katja K, Adair, Linda S, Alam, Dewan S, Albrecht, Eva, Allin, Kristine H, Allison, Matthew, Amouyel, Philippe, Appel, Emil V, Arveiler, Dominique, Asselbergs, Folkert W, Auer, Paul L, Balkau, Beverley, Banas, Bernhard, Bang, Lia E, Benn, Marianne, Bergmann, Sven, Bielak, Lawrence F, Blueher, Matthias, Boeing, Heiner, Boerwinkle, Eric, Boeger, Carsten A, Bonnycastle, Lori L, Bork-Jensen, Jette, Bots, Michiel L, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Breen, Gerome, Brilliant, Murray H, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Carey, David J, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cocca, Massimiliano, Collins, Francis S, Cook, James P, Corley, Janie, Galbany, Jordi Corominas, Cox, Amanda J, Cuellar-Partida, Gabriel, Danesh, John, Davies, Gail, de Bakker, Paul IW, de Borst, Gert J, de Denus, Simon, de Groot, Mark CH, de Mutsert, Renee, Deary, Ian J, Dedoussis, George, Demerath, Ellen W, den Hollander, Anneke I, Dennis, Joe G, Di Angelantonio, Emanuele, Drenos, Fotios, Du, Mengmeng, Dunning, Alison M, Easton, Douglas F, Ebeling, Tapani, Edwards, Todd L, Ellinor, Patrick T, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Faul, Jessica D, Feitosa, Mary F, Feng, Shuang, Ferrannini, Ele, Ferrario, Marco M, Ferrieres, Jean, Florez, Jose C, Ford, Ian, Fornage, Myriam, Franks, Paul W, Frikke-Schmidt, Ruth, Galesloot, Tessel E, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Giri, Ayush, Girotto, Giorgia, Gordon, Scott D, Gordon-Larsen, Penny, Gorski, Mathias, Grarup, Niels, Grove, Megan L, Gudnason, Vilmundur, Gustafsson, Stefan, Hansen, Torben, Harris, Kathleen Mullan, Harris, Tamara B, Hattersley, Andrew T, Hayward, Caroline, He, Liang, Heid, Iris M, Heikkila, Kauko, Helgeland, Oyvind, Hernesniemi, Jussi, Hewitt, Alex W, Hocking, Lynne J, Hollensted, Mette, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hoyng, Carel B, Huang, Paul L, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jansson, Jan-Hakan, Jarvik, Gail P, Jensen, Gorm B, Jhun, Min A, Jia, Yucheng, Jiang, Xuejuan, Johansson, Stefan, Jorgensen, Marit E, Jorgensen, Torben, Jousilahti, Pekka, Jukema, J Wouter, Kahali, Bratati, Kahn, Rene S, Kahonen, Mika, Kamstrup, Pia R, Kanoni, Stavroula, Kaprio, Jaakko, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Keeman, Renske, Kiemeney, Lambertus A, Kitajima, Hidetoshi, Kluivers, Kirsten B, Kocher, Thomas, Komulainen, Pirjo, Kontto, Jukka, Kooner, Jaspal S, Kooperberg, Charles, Kovacs, Peter, Kriebel, Jennifer, Kuivaniemi, Helena, Kury, Sebastien, Kuusisto, Johanna, La Bianca, Martina, Laakso, Markku, Lakka, Timo A, Lange, Ethan M, Lange, Leslie A, Langefeld, Carl D, Langenberg, Claudia, Larson, Eric B, Lee, I-Te, Lehtimaki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Honghuang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindstrom, Jaana, Linneberg, Allan, Liu, Yeheng, Liu, Yongmei, Lophatananon, Artitaya, Luan, Jian'an, Lubitz, Steven A, Lyytikainen, Leo-Pekka, Mackey, David A, Madden, Pamela AF, Manning, Alisa K, Mannisto, Satu, Marenne, Gaelle, Marten, Jonathan, Martin, Nicholas G, Mazul, Angela L, Meidtner, Karina, Metspalu, Andres, Mitchell, Paul, Mohlke, Karen L, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew D, Morris, Andrew P, Mueller-Nurasyid, Martina, Munroe, Patricia B, Nalls, Mike A, Nauck, Matthias, Nelson, Christopher P, Neville, Matt, Nielsen, Sune F, Nikus, Kjell, Njolstad, Pal R, Nordestgaard, Borge G, Ntalla, Ioanna, O'Connel, Jeffrey R, Oksa, Heikki, Loohuis, Loes M Olde, Ophoff, Roel A, Owen, Katharine R, Packard, Chris J, Padmanabhan, Sandosh, Palmer, Colin NA, Pasterkamp, Gerard, Patel, Aniruddh P, Pattie, Alison, Pedersen, Oluf, Peissig, Peggy L, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Person, Thomas N, Pirie, Ailith, Polasek, Ozren, Posthuma, Danielle, Raitakari, Olli T, Rasheed, Asif, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Renstrom, Frida, Ridker, Paul M, Rioux, John D, Robertson, Neil, Robino, Antonietta, Rolandsson, Olov, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Sandow, Kevin, Sapkota, Yadav, Sattar, Naveed, Schmidt, Marjanka K, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo P, Shah, Svati, Sim, Xueling, Sivapalaratnam, Suthesh, Small, Kerrin S, Smith, Albert Vernon, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Starr, John M, Steinthorsdottir, Valgerdur, Stringham, Heather M, Stumvoll, Michael, Surendran, Praveen, 't Hart, Leen M, Tansey, Katherine E, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorsteinsdottir, Unnur, Thuesen, Betina H, Toenjes, Anke, Tromp, Gerard, Trompet, Stella, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Tybjaerg-Hansen, Anne, Tyrer, Jonathan P, Uher, Rudolf, Uitterlinden, Andre G, Ulivi, Sheila, van der Laan, Sander W, Van Der Leij, Andries R, van Duijn, Cornelia M, van Schoor, Natasja M, van Setten, Jessica, Varbo, Anette, Varga, Tibor V, Varma, Rohit, Edwards, Digna R Velez, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vozzi, Diego, Walker, Mark, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wang, Yiqin, Wareham, Nicholas J, Warren, Helen R, Wessel, Jennifer, Willems, Sara M, Wilson, James G, Witte, Daniel R, Woods, Michael O, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yao, Pang, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Rotter, Jerome I, Boehnke, Michael, Kathiresan, Sekar, McCarthy, Mark I, Willer, Cristen J, Stefansson, Kari, Borecki, Ingrid B, Liu, Dajiang J, North, Kari E, Heard-Costa, Nancy L, Pers, Tune H, Lindgren, Cecilia M, Oxvig, Claus, Kutalik, Zoltan, Rivadeneira, Fernando, Loos, Ruth JF, Frayling, Timothy M, Hirschhorn, Joel N, Deloukas, Panos, Lettre, Guillaume, Consortium, EPIC-InterAct, Consortium, EPIC-CVD, Consortium, CHD Exome, Consortium, ExomeBP, Consortium, T2D-Genes, Consortium, GoT2D Genes, Consortium, Global Lipids Genetics, Consortium, ReproGen, Investigators, MAGIC

Publikováno v: Nature, 542, 186-190
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Li, J, Posthuma, D, van Schoor, N M & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjær, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Jørgensen, T & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Posthuma, D & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
NATURE
Nature, 542(7640), 186-190. Nature Publishing Group
Nature 542, 186-190 (2017)
Nature
Nature, vol 542, iss 7640
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V R, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Brandslund, I, Christensen, C, Hansen, T, Jensen, G B, Jørgensen, M E & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S M, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Oxvig, C & EPIC InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Böger, C A, Bonnycastle, L L, Bork-jensen, J, Bots, M L, Bottinger, E P, Bowden, D W, Brandslund, I, Breen, G, Brilliant, M H, Broer, L, Burt, A A, Butterworth, A S, Carey, D J, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y I, Chowdhury, R, Christensen, C, Chu, A Y, Cocca, M, Collins, F S, Cook, J P, Corley, J, Galbany, J C, Cox, A J, Cuellar-partida, G, Danesh, J, Davies, G, De Bakker, P I W, De Borst, G J, De Denus, S, De Groot, M C H, De Mutsert, R, Deary, I J, Dedoussis, G, Demerath, E W, Den Hollander, A I, Dennis, J G, Di Angelantonio, E, Drenos, F, Du, M, Dunning, A M, Easton, D F, Ebeling, T, Edwards, T L, Ellinor, P T, Elliott, P, Evangelou, E, Farmaki, A, Faul, J D, Feitosa, M F, Feng, S, Ferrannini, E, Ferrario, M M, Ferrieres, J, Florez, J C, Ford, I, Fornage, M, Franks, P W, Frikke-schmidt, R, Galesloot, T E, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Giri, A, Girotto, G, Gordon, S D, Gordon-larsen, P, Gorski, M, Grarup, N, Grove, M L, Gudnason, V, Gustafsson, S, Hansen, T, Harris, K M, Harris, T B, Hattersley, A T, Hayward, C, He, L, Heid, I M, Heikkilä, K, Helgeland, Ø, Hernesniemi, J, Hewitt, A W, Hocking, L J, Hollensted, M, Holmen, O L, Hovingh, G K, Howson, J M M, Hoyng, C B, Huang, P L, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jansson, J, Jarvik, G P, Jensen, G B, Jhun, M A, Jia, Y, Jiang, X, Johansson, S, Jørgensen, M E, Jørgensen, T, Jousilahti, P, Jukema, J W, Kahali, B, Kahn, R S, Kähönen, M, Kamstrup, P R, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Keeman, R, Kiemeney, L A, Kitajima, H, Kluivers, K B, Kocher, T, Komulainen, P, Kontto, J, Kooner, J S, Kooperberg, C, Kovacs, P, Kriebel, J, Kuivaniemi, H, Küry, S, Kuusisto, J, La Bianca, M, Laakso, M, Lakka, T A, Lange, E M, Lange, L A, Langefeld, C D, Langenberg, C, Larson, E B, Lee, I, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-gao, R, Lin, H, Lin, L, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, Y, Liu, Y, Lophatananon, A, Luan, J, Lubitz, S A, Lyytikäinen, L, Mackey, D A, Madden, P A F, Manning, A K, Männistö, S, Marenne, G, Marten, J, Martin, N G, Mazul, A L, Meidtner, K, Metspalu, A, Mitchell, P, Mohlke, K L, Mook-kanamori, D O, Morgan, A, Morris, A D, Morris, A P, Müller-nurasyid, M, Munroe, P B, Nalls, M A, Nauck, M, Nelson, C P, Neville, M, Nielsen, S F, Nikus, K, Njølstad, P R, Nordestgaard, B G, Ntalla, I, O'connel, J R, Oksa, H, Loohuis, L M O, Ophoff, R A, Owen, K R, Packard, C J, Padmanabhan, S, Palmer, C N A, Pasterkamp, G, Patel, A P, Pattie, A, Pedersen, O, Peissig, P L, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Person, T N, Pirie, A, Polasek, O, Posthuma, D, Raitakari, O T, Rasheed, A, Rauramaa, R, Reilly, D F, Reiner, A P, Renström, F, Ridker, P M, Rioux, J D, Robertson, N, Robino, A, Rolandsson, O, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Sandow, K, Sapkota, Y, Sattar, N, Schmidt, M K, Schreiner, P J, Schulze, M B, Scott, R A, Segura-lepe, M P, Shah, S, Sim, X, Sivapalaratnam, S, Small, K S, Smith, A V, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Steinthorsdottir, V, Stringham, H M, Stumvoll, M, Surendran, P, ‘t Hart, L M, Tansey, K E, Tardif, J, Taylor, K D, Teumer, A, Thompson, D J, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-hansen, A, Tyrer, J P, Uher, R, Uitterlinden, A G, Ulivi, S, Van Der Laan, S W, Van Der Leij, A R, Van Duijn, C M, Van Schoor, N M, Van Setten, J, Varbo, A, Varga, T V, Varma, R, Edwards, D R V, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vozzi, D, Walker, M, Wang, F, Wang, C A, Wang, S, Wang, Y, Wareham, N J, Warren, H R, Wessel, J, Willems, S M, Wilson, J G, Witte, D R, Woods, M O, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, J H, Zhao, W, Zhao, W, Zheng, H, Zhou, W, Rotter, J I, Boehnke, M, Kathiresan, S, Mccarthy, M I, Willer, C J, Stefansson, K, Borecki, I B, Liu, D J, North, K E, Heard-costa, N L, Pers, T H, Lindgren, C M, Oxvig, C, Kutalik, Z, Rivadeneira, F, Loos, R J F, Frayling, T M, Hirschhorn, J N, Deloukas, P & Lettre, G 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542(7640), 186-190
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Lophatananon, A & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542, 7640, pp. 186-190
Nature, 542(7640), 186. Nature Research
Nature, vol. 542, no. 7640, pp. 186-190
Marouli, E; Graff, M; Medina-Gomez, C; Lo, KS; Wood, AR; Kjaer, TR; et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature, 542(7640), 186-190. doi: 10.1038/nature21039. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1sq5r8fb
Nature, 542, 186. Nature Publishing Group

Contains fulltext : 169801.pdf (Publisher’s version ) (Closed access) Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report

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https://doi.org/10.1038/nature21039

Prevalence and extent of infarct and microvascular obstruction following different reperfusion therapies in ST-elevation myocardial infarction.

Autor: Khan, Jamal N., Razvi, Naveed, Nazir, Sheraz A., Singh, Anvesha, Masca, Nicholas GD, Gershlick, Anthony H., Squire, Iain, McCann, Gerry P.

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