Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicholas G. Robinson"'
Autor:
Monique S. J. Simmonds, Wally M. Blaney, James C. Anderson, Dinos Santafianos, Nicholas G. Robinson, Zev Lidert, Steven V. Ley, Philip Jones, Peter L. Toogood, E. David Morgan
Publikováno v:
Tetrahedron. 45:5175-5192
Chemical modification of the potent insect antifeedant and growth-disruption agent azadirachtin (1) and the related limonoids 3-tigloyl azadirachtol (6) and salannin (27) have permitted an exploration of the biological activity of these compounds. Ge
Publikováno v:
J. Chem. Soc., Chem. Commun.. :1664-1667
A series of structural variants of the cysteinyl moiety of the natural precursor of penicillins, δ(L-α-aminoadipoyl)-L-cysteinyl-D-valine, have been synthesised and their effectiveness as substrates for the enzyme isopenicillin N synthetase has bee
Publikováno v:
Tetrahedron Letters. 29:1849-1852
The conversion of azadirachtin derivatives to the corresponding azadirachtinin skeletons can be achieved in high yield under mild conditions.
Autor:
Wally M. Blaney, Zev Lidert, Steven V. Ley, Monique S. J. Simmonds, E. David Morgan, James C. Anderson, Nicholas G. Robinson
Publikováno v:
Tetrahedron Letters. 29:5433-5436
Azadirachtin (1) can be converted to the natural product 22,23-dihydro-23β-methoxyazadirachtin (2) via selective bromomethoxylation of the C-22,23 enol ether double bond and tri-n-butyltin hydride reduction; the corresponding acetic acid adduct on p
Autor:
Zev Lidert, Philip Jones, Monique S. J. Simmonds, W. M. Blaney, Peter L. Toogood, Nicholas G. Robinson, Steven V. Ley, James C. Anderson, Dinos Santafianos, E. D. Morgan
Publikováno v:
ChemInform. 20
Publikováno v:
ChemInform. 19
The stereospecific addition of a glycine anion equivalent to a β-ribosyl acrylate is the key step in the enantiospecific synthesis of L -3-(β- D -ribofuranosyl)-pyroglutamic acids, possible intermediates in C-nucleoside biosynthesis.
Publikováno v:
ChemInform. 18
Reaction of N-tosyl- or N-acyl aziridine-(2S)-carboxylate esters with carbonyl stabilized Wittig reagents provides an isolable phosphorus ylide resulting from opening of the aziridine ring; this ylide reacts with carbonyl compounds to provide a novel
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :153
Reaction of N-tosyl- or N-acyl aziridine-(2S)-carboxylate esters with carbonyl stabilized Wittig reagents provides an isolable phosphorus ylide resulting from opening of the aziridine ring; this ylide reacts with carbonyl compounds to provide a novel