Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nicholas G. Jentsch"'
Autor:
Nicholas G. Jentsch, Jared D. Hume, Emily B. Crull, Samer M. Beauti, Amy H. Pham, Julie A. Pigza, Jacques J. Kessl, Matthew G. Donahue
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has been developed starting from commercially available 2-aminobenzoic acids. In step 1, the anthranilic acids are smoothly converted to isatoic anhydrides
Externí odkaz:
https://doaj.org/article/fbd91e864cd84c9da84a118b40063aa4
Publikováno v:
Journal of Natural Products. 83:2587-2591
The synthesis of three phenolic natural products has been accomplished with unprecedented efficiency using a new alumina-promoted regioselective aromatic allylation reaction. Cannabigerol and grifolin were prepared in one step from the inexpensive 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b5e326e98616d3aad7e0219f9c94e1
https://doi.org/10.1021/acs.jnatprod.0c00131
https://doi.org/10.1021/acs.jnatprod.0c00131
Autor:
Hebatallah Mohamed, Jia Zhou, Haiying Chen, Nicholas G. Jentsch, Stephen Boulton, Stephen J. Yarwood, Urszula Luchowska-Stańska, Jinfeng Huang, Pingyuan Wang, Alison L. Armstrong, Giuseppe Melacini, Hongzhao Shao, Jakob Magolan
Publikováno v:
Journal of Medicinal Chemistry. 63:4762-4775
The exchange protein activated by cAMP (EPAC) is a promising drug target for a wide disease range, from neurodegeneration and infections to cancer and cardiovascular conditions. A novel partial agonist of the EPAC isoform 1 (EPAC1), I942, was recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d4956b873f9344abc9701e190161a
https://doi.org/10.1021/acs.jmedchem.9b02151
https://doi.org/10.1021/acs.jmedchem.9b02151
Autor:
Maya A. Farha, Lindsey A. Carfrae, Nicholas G. Jentsch, Jakob Magolan, Craig R. MacNair, Omar M. El-Halfawy, Eric D. Brown, Robert T. Gale, Xiong Zhang
Publikováno v:
ACS Infectious Diseases. 6:338-346
The spread of antimicrobial resistance continues to be a priority health concern worldwide, necessitating exploration of alternative therapies. Cannabis sativa has long been known to contain antibacterial cannabinoids, but their potential to address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f973ffea8c2fcd19160c257eaee23210
https://doi.org/10.1021/acsinfecdis.9b00419
https://doi.org/10.1021/acsinfecdis.9b00419
Autor:
Gale G. Bozzo, Cameron Parry, Eric Soubeyrand, Taylor J B Forrester, Jakob Magolan, Matthew S. Kimber, Tariq A. Akhtar, Steven J. Rothstein, M. Sameer Al-Abdul-Wahid, Nicholas G. Jentsch, Colby Perrin, Kelly F. Boddington, Kristen Van Gelder, José A. Casaretto
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 109(3)
This study focuses on the biosynthesis of a suite of specialized metabolites from Cannabis that are known as the 'bibenzyls'. In planta, bibenzyls accumulate in response to fungal infection and various other biotic stressors; however, it is their wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828d2a74b3296bd7a522aec174311b5
https://pubmed.ncbi.nlm.nih.gov/34786774
https://pubmed.ncbi.nlm.nih.gov/34786774
Autor:
Jian Sun, Jacques J. Kessl, Kaitlin A McNeely, Julie A. Pigza, Nicholas G. Jentsch, Chiyang Lama, Jared D. Hume, Alison P Hart, Matthew Garrett Donahue
Publikováno v:
ACS Medicinal Chemistry Letters. 9:1007-1012
[Image: see text] HIV-1 integrase multimerization inhibitors have recently been established as an effective class of antiretroviral agents due to their potent ability to inhibit viral replication. Specifically, quinoline-based inhibitors have been sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff79914f4d441c9d2d1e09908647b7
https://doi.org/10.1021/acsmedchemlett.8b00269
https://doi.org/10.1021/acsmedchemlett.8b00269
Publikováno v:
Tetrahedron Letters. 58:3219-3222
A Tsuji-Trost variant of the Winstein-Masamune reaction has been investigated for the synthesis of the AC spirocyclic ring system 9 bearing a quaternary carbon found in the fawcettimine type Lycopodium alkaloids magellanine 1 and lycojaponicumin B 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7d8b076a1d18a875d37856e86d971d
https://doi.org/10.1016/j.tetlet.2017.07.003
https://doi.org/10.1016/j.tetlet.2017.07.003
Publikováno v:
Tetrahedron Letters. 58:1692-1694
The synthesis of [ 13 C 6 ]3,4-diaminobenzoic acid from commercially available [ 13 C 6 ]aniline is described in six steps. Salient features of this route include the preparation of a differentially protected 3,4-diaminobenzonitrile, hydrogen gas fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13eb1e5d837b3596df1e6bc1a6199dcd
https://doi.org/10.1016/j.tetlet.2017.03.045
https://doi.org/10.1016/j.tetlet.2017.03.045
Autor:
Emily B. Crull, Samer M. Beauti, Jared D. Hume, Amy H. Pham, Jacques J. Kessl, Nicholas G. Jentsch, Matthew Garrett Donahue, Julie A. Pigza
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2529-2536 (2018)
A convenient two-step synthesis of ethyl 4-hydroxy-2-methylquinoline-3-carboxylate derivatives has been developed starting from commercially available 2-aminobenzoic acids. In step 1, the anthranilic acids are smoothly converted to isatoic anhydrides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ae380e1f278bb6b26e9c640fdc1393
https://pubmed.ncbi.nlm.nih.gov/30344776
https://pubmed.ncbi.nlm.nih.gov/30344776
