Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicholas F S Watson"'
Autor:
John Trowsdale, Graham Ball, Robert A. Eagle, Ahmad Al-Attar, Insiya Jafferji, Roger McGilvray, Lindy G. Durrant, Nicholas F S Watson
Publikováno v:
Clinical Cancer Research. 15:6993-7002
Purpose: NKG2D (natural killer group 2, member D) binds to cellular ligands of the MIC and ULBP/RAET family. These ligands have restricted expression in normal tissue, but are frequently expressed on primary tumors. The role of NKG2D ligands is thoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21529f74c9c07e73651e4e81d4a84424
https://doi.org/10.1158/1078-0432.ccr-09-0991
https://doi.org/10.1158/1078-0432.ccr-09-0991
Autor:
Ian Spendlove, Gustav J. Ullenhag, Lindy G. Durrant, Mukul G. Dube, Charles Maxwell-Armstrong, R. A. Robins, John H. Scholefield, Nicholas F S Watson, Adrian A. Indar
Publikováno v:
Clinical Cancer Research. 12:7389-7396
Purpose: To assess the tolerability and effectiveness of 105AD7 vaccination in colorectal cancer patients. 105AD7 is a human anti-idiotypic antibody mimicking CD55, a glycoprotein, which is more than expressed on colorectal cancer cells and protects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e08184f5ddbb68d5515f46e6a8f1897
https://doi.org/10.1158/1078-0432.ccr-06-1003
https://doi.org/10.1158/1078-0432.ccr-06-1003
Autor:
Lindy G. Durrant, Ian O. Ellis, John H. Scholefield, Ian Spendlove, Zahra Madjd, Nicholas F S Watson
Publikováno v:
Cancer Immunology, Immunotherapy. 55:973-980
It has been known for some time that the immune system can recognise growing tumours, and that tumours may respond by modulation of molecules, which make them resistant to further attack. Expression, over-expression, or loss of these molecules may fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb924c84c19b4cf2873e61ab025019e3
https://doi.org/10.1007/s00262-005-0055-0
https://doi.org/10.1007/s00262-005-0055-0
Background and aims Endoscopy performance is dependent on the technical ability and experience of the operator. There is anxiety among surgical trainees that certification to perform independent endoscopy to agreed national standards by the date of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bf8f389362d642e0d84b6dfa62fbb9
https://europepmc.org/articles/PMC5369786/
https://europepmc.org/articles/PMC5369786/
Autor:
Iain Au-Yong, Simon C. Whitaker, Timothy E. Bowling, John F Abercrombie, Catherine L Boereboom, Nicholas F S Watson
Publikováno v:
World Journal of Emergency Surgery, Vol 5, Iss 1, p 7 (2010)
World Journal of Emergency Surgery : WJES
World Journal of Emergency Surgery : WJES
Pseudoaneurysms related to the superior mesenteric artery (SMA) are a recognised complication of trauma to the vessel, and successful treatment with stenting has been previously described. We report the case of a patient who presented with obstructio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1309c15eceb193722f317605e400f5a0
https://doi.org/10.1186/1749-7922-5-7
https://doi.org/10.1186/1749-7922-5-7
Autor:
Nicholas F S Watson, Ahmad Al-Attar, Mohamed A. H. Ahmed, Lindy G. Durrant, J Kim, John H. Scholefield, Mohammad Ilyas
Publikováno v:
Journal of clinical pathology. 62(12)
Background and aims: The putative stem cell marker CD24 is a small, heavily glycosylated, cell surface molecule which was originally associated with tumour metastasis. Recently it has been reported to be upregulated and of prognostic importance in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4e49512ba42a3841547e1bbdbed18e
https://pubmed.ncbi.nlm.nih.gov/19946098
https://pubmed.ncbi.nlm.nih.gov/19946098
Autor:
John Hammond, Charles Maxwell-Armstrong, Nicholas F S Watson, Adam Brooks, John F Abercrombie
Jansen et al highlight the potential difficulty of diagnosing intraperitoneal bleeding and hollow viscus injuries in patients with blunt abdominal trauma.1 Despite an increasing use of point of care focused assessment with sonography for trauma (FAST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c592078cadc2a6b1927fbf0176251fd2
https://europepmc.org/articles/PMC2386648/
https://europepmc.org/articles/PMC2386648/
Autor:
Lindy G. Durrant, Kathy Pritchard-Jones, Nicholas F S Watson, C. Kallmeyer, Gustav J. Ullenhag, Ian Spendlove
Publikováno v:
Clinical immunology (Orlando, Fla.). 128(2)
We assessed T-cell responses in young osteosarcoma patients vaccinated with 105AD7, 1-6months after having received chemotherapy. 105AD7 is a human anti-idiotypic antibody mimicking CD55, a glycoprotein that protects from attack by complement and whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5746c83c9977d500623ece931008d2e2
https://pubmed.ncbi.nlm.nih.gov/18508409
https://pubmed.ncbi.nlm.nih.gov/18508409
Autor:
John H. Scholefield, Nicholas F S Watson, Abhik Mukherjee, Gustave J. Ullenhag, Lindy G. Durrant, Ahmad Al-Attar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(17)
Purpose: Colorectal cancer is one of the most common cancers. The tumor necrosis factor–related apoptosis inducing ligand (TRAIL) pathway transmits apoptotic signals and anticancer agents that activate this system, which are in clinical development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6293ad4a8584c1528b038c99d22ea3
https://pubmed.ncbi.nlm.nih.gov/17785559
https://pubmed.ncbi.nlm.nih.gov/17785559
Autor:
Ian Spendlove, Poulam M. Patel, Duncan Scrimgeour, Nicholas F S Watson, Lindy G. Durrant, Ian O. Ellis, John H. Scholefield, Zahra Madjd
Publikováno v:
World journal of gastroenterology. 12(39)
To evaluate the prognostic significance of p27(kip1) in colorectal cancer patients.Cytoplasmic and nuclear p27(kip1) expression was evaluated in 418 colorectal cancers using tissue microarrays. Data were associated with known patient and tumor variab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1eae2d1cc287d9feac4f6fe17be6987
https://pubmed.ncbi.nlm.nih.gov/17072952
https://pubmed.ncbi.nlm.nih.gov/17072952