Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Nicholas E. Sherman"'
Autor:
Sabrina Curreli, Francesca Benedetti, Weirong Yuan, Arshi Munawwar, Fiorenza Cocchi, Robert C. Gallo, Nicholas E. Sherman, Davide Zella
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Chaperone proteins are redundant in nature and, to achieve their function, they bind a large repertoire of client proteins. DnaK is a bacterial chaperone protein that recognizes misfolded and aggregated proteins and drives their folding and intracell
Externí odkaz:
https://doaj.org/article/abec0edc5d6749ed9a400200fa1d41c8
Autor:
Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton, Bryce M. Paschal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.
Externí odkaz:
https://doaj.org/article/4e3161d87a9e495bb19ec9d697ca2a8c
Autor:
Ting-Ting Du, James B. Dewey, Elizabeth L. Wagner, Runjia Cui, Jinho Heo, Jeong-Jin Park, Shimon P. Francis, Edward Perez-Reyes, Stacey J. Guillot, Nicholas E. Sherman, Wenhao Xu, John S Oghalai, Bechara Kachar, Jung-Bum Shin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In contrast to the extensively studied mechanosensory hair bundle, the cuticular plate is not as well understood. In this study, authors describe the discovery of a hair cell protein called LIM only protein 7, which is localized in the cuticular plat
Externí odkaz:
https://doaj.org/article/c2ec714b45bc41bf96953f0212beec8a
Autor:
Nitin Joshi, Jing Yan, Seth Levy, Sachin Bhagchandani, Kai V. Slaughter, Nicholas E. Sherman, Julian Amirault, Yufeng Wang, Logan Riegel, Xueyin He, Tan Shi Rui, Michael Valic, Praveen K. Vemula, Oscar R. Miranda, Oren Levy, Ellen M. Gravallese, Antonios O. Aliprantis, Joerg Ermann, Jeffrey M. Karp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.
Externí odkaz:
https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c91
Autor:
Sarah N. C. Gimenes, Jacqueline A. G. Sachett, Mônica Colombini, Luciana A. Freitas-de-Sousa, Hiochelson N. S. Ibiapina, Allyson G. Costa, Monique F. Santana, Jeong-Jin Park, Nicholas E. Sherman, Luiz C. L. Ferreira, Fan H. Wen, Wuelton M. Monteiro, Ana M. Moura-da-Silva, Jay W. Fox
Publikováno v:
Toxins, Vol 13, Iss 11, p 800 (2021)
In the Brazilian Amazon, Bothrops atrox snakebites are frequent, and patients develop tissue damage with blisters sometimes observed in the proximity of the wound. Antivenoms do not seem to impact blister formation, raising questions regarding the me
Externí odkaz:
https://doaj.org/article/e2d38df7b19d40e8be2eb5fde135cb1d
Autor:
Oluwatoyin E. Akande, Priyadarshan K. Damle, Marius Pop, Nicholas E. Sherman, Barbara B. Szomju, Larisa V. Litovchick, Steven R. Grossman
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3323-3335.e4 (2019)
Summary: The control of p53 protein stability is critical to its tumor suppressor functions. The CREB binding protein (CBP) transcriptional co-activator co-operates with MDM2 to maintain normally low physiological p53 levels in cells via exclusively
Externí odkaz:
https://doaj.org/article/4253af2631464865a6032687bd2ff8cc
Autor:
Andrew D. Catling, Nicholas E. Sherman, Evangeline Bailey, Daviel Cardenas, Ashok K. Pullikuth, Aysun Ozdemir, K. Kevin Pfister
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3595-3620 (2013)
Extracellular-signal regulated kinase (ERK) signaling is required for a multitude of physiological and patho-physiological processes. However, the identities of the proteins that ERK phosphorylates to elicit these responses are incompletely known. Us
Externí odkaz:
https://doaj.org/article/27bf5c40eb104c6eab24a2d308aea600
Autor:
Nitin Joshi, Jing Yan, Seth Levy, Sachin Bhagchandani, Kai V. Slaughter, Nicholas E. Sherman, Julian Amirault, Yufeng Wang, Logan Riegel, Xueyin He, Tan Shi Rui, Michael Valic, Praveen K. Vemula, Oscar R. Miranda, Oren Levy, Ellen M. Gravallese, Antonios O. Aliprantis, Joerg Ermann, Jeffrey M. Karp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include support from the National Football League Players Association.
Externí odkaz:
https://doaj.org/article/f879506585b44852bebc90142ed728f6
Autor:
Jayasimha eRao, F. Heath Damron, Marek eBasler, Antonio eDiGiandomenico, Nicholas E. Sherman, Jay W. Fox, John J. Mekalanos, Joanna B. Goldberg
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Pseudomonas aeruginosa chronically infects the lungs of cystic fibrosis (CF) patients. The conditions in the CF lung appear to select for P. aeruginosa with advantageous phenotypes for chronic infection. However, the mechanisms that allow the establi
Externí odkaz:
https://doaj.org/article/932f12394fcf435d9f36b3a132ff5723
Publikováno v:
Physical Review B. 107