Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicholas E. Mamrak"'
Autor:
Sudarshan Pinglay, Milica Bulajić, Dylan P. Rahe, Emily Huang, Ran Brosh, Nicholas E. Mamrak, Benjamin R. King, Sergei German, John A. Cadley, Lila Rieber, Nicole Easo, Timothée Lionnet, Shaun Mahony, Matthew T. Maurano, Liam J. Holt, Esteban O. Mazzoni, Jef D. Boeke
Publikováno v:
Science
INTRODUCTION: Despite an ever-expanding catalog of noncoding elements that are implicated in the control of mammalian gene expression, how the regulatory input from multiple elements is integrated across a genomic neighborhood has remained largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7772d22daf61c45f770cf5e49e7233
https://doi.org/10.1126/science.abk2820
https://doi.org/10.1126/science.abk2820
Autor:
Nicholas E Mamrak, Nader Alerasool, Daniel Griffith, Alex S Holehouse, Mikko Taipale, Timothée Lionnet
Cell-to-cell variability is shaped by transcription dynamics because genes are transcribed in bursts interspersed with inactive periods. The stochasticity of bursting means that genes transcribed in rare bursts exhibit more heterogeneity at the singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec105ea0409f5a075626843d82287701
https://doi.org/10.1101/2022.06.01.494187
https://doi.org/10.1101/2022.06.01.494187
Publikováno v:
Blood Reviews. 31:93-99
Fanconi anemia (FA) is a rare autosomal and X-linked genetic disease characterized by congenital abnormalities, progressive bone marrow failure (BMF), and increased cancer risk during early adulthood. The median lifespan for FA patients is approximat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a6039e8663245fa2c1fefe2bf31aa
https://doi.org/10.1016/j.blre.2016.10.002
https://doi.org/10.1016/j.blre.2016.10.002
Autor:
Karissa L. Paquin, Jodi L. Camberg, Elizabeth A Vuono, Jada L. Garzon, Nicholas E. Mamrak, Niall G. Howlett, Juan A. Cantres-Velez, Kevin E. Lima, Paul A. Azzinaro
Publikováno v:
Molecular and Cellular Biology. 39
Fanconi anemia (FA) is an inherited disease characterized by bone marrow failure and increased cancer risk. FA is caused by mutation of any 1 of 22 genes, and the FA proteins function cooperatively to repair DNA interstrand cross-links (ICLs). A cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2592ba2767af32362b63046d7f8734f
https://doi.org/10.1128/mcb.00194-19
https://doi.org/10.1128/mcb.00194-19