Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nicholas E. Lea"'
Autor:
Lei Jin, Heather A. Sullivan, Mulangma Zhu, Nicholas E. Lea, Thomas K. Lavin, Xin Fu, Makoto Matsuyama, YuanYuan Hou, Guoping Feng, Ian R. Wickersham
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 11, Pp 100644- (2023)
Summary: Rabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid
Externí odkaz:
https://doaj.org/article/933dc6b926c64e9a8fda4a668cda7b95
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Monosynaptically-restricted transsynaptic tracing using deletion-mutant rabies virus (RV) has become a widely used technique in neuroscience, allowing identification, imaging, and manipulation of neurons directly presynaptic to a starting neuronal po
Externí odkaz:
https://doaj.org/article/f5589ee29fd346d3bc720563db46a210
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT In many bacterial species, the glycine riboswitch is composed of two homologous ligand-binding domains (aptamers) that each bind glycine and act together to regulate the expression of glycine metabolic and transport genes. While the structur
Externí odkaz:
https://doaj.org/article/d0a9a7384d9d41f9a6062a84360361e7
Autor:
Mulangma Zhu, María Lucía Dam Ferdínez, Heather A. Sullivan, Thomas K. Lavin, Lei Jin, Nicholas E. Lea, YuanYuan Hou, Maxwell T. Pruner, Makoto Matsuyama, Ian R. Wickersham
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Monosynaptic tracing using rabies virus is an important technique in neuroscience, allowing brain- wide labeling of neurons directly presynaptic to a targeted neuronal population. A 2017 article reported development of a noncytotoxic version – a ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40df4787a327947c04642a8c0e40552
https://doi.org/10.1073/pnas.2023481120
https://doi.org/10.1073/pnas.2023481120
Autor:
Ying Zhang, Dheeraj S. Roy, Yi Zhu, Yefei Chen, Tomomi Aida, Yuanyuan Hou, Chenjie Shen, Nicholas E. Lea, Margaret E. Schroeder, Keith M. Skaggs, Heather A. Sullivan, Kyle B. Fischer, Edward M. Callaway, Ian R. Wickersham, Ji Dai, Xiao-Ming Li, Zhonghua Lu, Guoping Feng
Publikováno v:
Nature
Although bradykinesia, tremor, and rigidity are the hallmark motor defects in Parkinson’s disease (PD) patients, they also experience motor learning impairments and non-motor symptoms such as depression(1). The neural circuit basis for these differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a045ec54d2bef435e0515273dbc4cd9f
https://europepmc.org/articles/PMC9403858/
https://europepmc.org/articles/PMC9403858/
Autor:
Lei Jin, Heather A. Sullivan, Mulangma Zhu, Nicholas E. Lea, Thomas K. Lavin, Makoto Matsuyama, YuanYuan Hou, Ian R. Wickersham
SUMMARYRabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d17277edf2cd9b2b123930695516ee8c
https://doi.org/10.1101/2022.02.23.481706
https://doi.org/10.1101/2022.02.23.481706
Autor:
Lei Jin, Heather A. Sullivan, Mulangma Zhu, Thomas K. Lavin, Makoto Matsuyama, Xin Fu, Nicholas E. Lea, Ran Xu, YuanYuan Hou, Luca Rutigliani, Maxwell Pruner, Kelsey R. Babcock, Jacque Pak Kan Ip, Ming Hu, Tanya L. Daigle, Hongkui Zeng, Mriganka Sur, Guoping Feng, Ian R. Wickersham
Monosynaptic tracing is a widely-used technique for mapping neural circuitry, but its cytotoxicity has confined it primarily to anatomical applications. Here we present a second-generation system for labeling direct inputs to targeted neuronal popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf87526a0041583d4e51597bbee81fd
https://doi.org/10.1101/2021.12.04.471186
https://doi.org/10.1101/2021.12.04.471186
Publikováno v:
SynOpen, Vol 07, Iss 04, Pp 718-722 (2023)
Externí odkaz:
https://doaj.org/article/c5cfa04a4f0c4282943bd37d4b868bd3
Autor:
Ian R. Wickersham, Steven A. McCarroll, Carter Jones, Nicholas E. Lea, Juliana C. Quay, Arpiar Saunders, Hannah Maisano, Qian Chen, Keith Skaggs, Heather A. Sullivan, Dong Kong, YuanYuan Hou, Vinh Le, Ying Zhang, Tomomi Aida, Soon-Wook Choi, Dheeraj S. Roy, Min Liew, Guoping Feng, Jie Xu
Publikováno v:
Neuron
Neuropsychiatric disorders are often accompanied by cognitive impairments/intellectual disability (ID). It is not clear whether there are converging mechanisms underlying these debilitating impairments. We found that many autism and schizophrenia ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624c6a13afb2de34f3a53f90319f518f
https://pubmed.ncbi.nlm.nih.gov/34197733
https://pubmed.ncbi.nlm.nih.gov/34197733
Publikováno v:
Frontiers in Synaptic Neuroscience
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Monosynaptically-restricted transsynaptic tracing using deletion-mutant rabies virus has become a widely used technique in neuroscience, allowing identification, imaging, and manipulation of neurons directly presynaptic to a starting neuronal populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af77b2fe8dae116d1c6ab11dc30b98c
http://europepmc.org/articles/PMC7033752
http://europepmc.org/articles/PMC7033752