Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Nicholas E. Banovich"'
Autor:
Margarita Gutova, Jonathan C. Hibbard, Eric Ma, Heini M. Natri, Vikram Adhikarla, Nyam-Osor Chimge, Runxiang Qiu, Cu Nguyen, Elizabeth Melendez, Brenda Aguilar, Renate Starr, Holly Yin, Russel C. Rockne, Masaya Ono, Nicholas E. Banovich, Yate-Ching Yuan, Christine E. Brown, Michael Kahn
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite aggressive standard-of-care therapy, including surgery, radiation, and chemotherapy, glioblastoma recurrence is almost inevitable and uniformly lethal. Activation of glioma-intrinsic Wnt/β-catenin signaling is associated with a p
Externí odkaz:
https://doaj.org/article/46059b87db0348ce905d3e52ef396589
Autor:
Erping Long, Montserrat García-Closas, Stephen J. Chanock, M. Constanza Camargo, Nicholas E. Banovich, Jiyeon Choi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Tissue-based functional genomics resources including molecular quantitative trait loci datasets lack diversity in ancestry and tissue types and thus are inadequate for comprehensively investigating gene regulation. Global efforts to increase the tiss
Externí odkaz:
https://doaj.org/article/dd0dd5bf17d247a6862b9b6cc70e9726
Autor:
Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 and poor outcomes. Here the authors compare the transcriptomes of single cells isolated from healthy and CLD lungs to identify molecular characteristics
Externí odkaz:
https://doaj.org/article/8c96b7d10ceb4972b8de290313cf45fb
Autor:
Qi Liu, Yuan Zhou, Joy D. Cogan, Daphne B. Mitchell, Quanhu Sheng, Shilin Zhao, Youhuang Bai, Kristen K. Ciombor, Carleen M. Sabusap, M. Merced Malabanan, Cheryl R. Markin, Katrina Douglas, Guixiao Ding, Nicholas E. Banovich, Deborah A. Nickerson, Elizabeth E. Blue, Michael J. Bamshad, Kevin K. Brown, David A. Schwartz, John A. Phillips, Ruben Martinez-Barricarte, Margaret L. Salisbury, Yu Shyr, James E. Loyd, Jonathan A. Kropski, Timothy S. Blackwell
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:1345-1357
Up to 20% of idiopathic interstitial lung disease is familial, referred to as Familial Pulmonary Fibrosis (FPF). We performed an integrated analysis of FPF genetic risk by comprehensively evaluating for genetic rare variants (RVs) in a large cohort o
Publikováno v:
eLife, Vol 10 (2021)
One life-threatening outcome of cardiovascular disease is myocardial infarction, where cardiomyocytes are deprived of oxygen. To study inter-individual differences in response to hypoxia, we established an in vitro model of induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/7a6642153f2e4c3f94845153f945fe39
Autor:
Toshio Suzuki, Jonathan A. Kropski, Jingyuan Chen, Erica J. Carrier, Xinping Chen, Taylor P. Sherrill, Nichelle I. Winters, Jane E. Camarata, Vasiliy V. Polosukhin, Wei Han, Anandharajan Rathinasabapathy, Sergey Gutor, Peter Gulleman, Carleen Sabusap, Nicholas E. Banovich, Harikrishna Tanjore, Michael L. Freeman, Yuji Tada, Lisa R. Young, Jason J. Gokey, Timothy S. Blackwell, James D. West
Publikováno v:
American journal of respiratory and critical care medicine. 206(5)
Autor:
Samantha L. Bucktrout, Nicholas E. Banovich, Lisa H. Butterfield, Cansu Cimen-Bozkus, Josephine R. Giles, Zinaida Good, Daniel Goodman, Vanessa D. Jonsson, Caleb Lareau, Alexander Marson, Denna M. Maurer, Paul V. Munson, Mike Stubbington, Sarah Taylor, Abbey Cutchin
Publikováno v:
Nature Medicine. 28:1761-1764
Autor:
Jessica B. Blackburn, Jacob A. Schaff, Sergey Gutor, Rui-Hong Du, David Nichols, Taylor Sherrill, Austin J. Gutierrez, Matthew K. Xin, Nancy Wickersham, Yong Zhang, Michael J. Holtzman, Lorraine B. Ware, Nicholas E. Banovich, Jonathan A. Kropski, Timothy S. Blackwell, Bradley W. Richmond
Publikováno v:
American journal of respiratory cell and molecular biology. 67(3)
Loss of secretory IgA (SIgA) is common in chronic obstructive pulmonary disease (COPD) small airways and likely contributes to disease progression. We hypothesized that loss of SIgA results from reduced expression of pIgR (polymeric immunoglobulin re
Autor:
Ana P. M. Serezani, Bruno D. Pascoalino, Julia M. R. Bazzano, Katherine N. Vowell, Harikrishna Tanjore, Chase J. Taylor, Carla L. Calvi, A. Scott McCall, Matthew D. Bacchetta, Ciara M. Shaver, Lorraine B. Ware, Margaret L. Salisbury, Nicholas E. Banovich, Peggy L. Kendall, Jonathan A. Kropski, Timothy S. Blackwell
Publikováno v:
Am J Respir Cell Mol Biol
Immune cells have been implicated in idiopathic pulmonary fibrosis (IPF), but the phenotypes and effector mechanisms of these cells remain incompletely characterized. We performed mass cytometry to quantify immune cell subsets in lungs of 12 patients
Autor:
Heini M Natri, Christina B Del Azodi, Lance Peter, Chase J Taylor, Sagrika Chugh, Robert Kendle, Mei-i Chung, David K Flaherty, Brittany K Matlock, Carla L Calvi, Timothy S Blackwell, Lorraine B Ware, Matthew Bacchetta, Rajat Walia, Ciara M Shaver, Jonathan A Kropski, Davis J McCarthy, Nicholas E Banovich
Publikováno v:
bioRxiv
Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis (PF). Defining the genetic control of gene expression in a cell-type-specific and context-dependent manner is critical for understanding the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb33f8d2914884f147f02fc19d6ac0f
https://europepmc.org/articles/PMC10055257/
https://europepmc.org/articles/PMC10055257/