Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicholas Delamere"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12870 (2022)
Lens ion homeostasis depends on Na,K-ATPase and NKCC1. TRPV4 and TRPV1 channels, which are mechanosensitive, play important roles in mechanisms that regulate the activity of these transporters. Here, we examined another mechanosensitive channel, piez
Externí odkaz:
https://doaj.org/article/1c7d99e487d74e6aa9f5a774fde135e7
Publikováno v:
Physiology. 38
Purpose: Previously we reported a mechanosensitive ion channel, TRPV4, along with functional connexin hemichannels on the NPE basolateral surface. In the lens, we have evidence of TRPV4-mediated hemichannel opening as part of a feedback mechanism tha
Publikováno v:
Physiology. 38
Purpose: Lens ion homeostasis is dependent on Na, K-ATPase and NKCC1. TRPV4 and TRPV1 channels, which are mechanosensitive, are known to regulate the activity of both these transporters. Here, we examined another mechanosensitive channel, piezo1, whi
Publikováno v:
Physiology. 38
ATP release from the lens via connexin hemichannels has been hypothesized as a response to TRPV4 activation when the lens is subjected to osmotic swelling. To explore the apparent linkage between TRPV4 activation and hemichannel opening we performed
Publikováno v:
The FASEB Journal. 36
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 2
Pages: 1673
Volume 24
Issue 2
Pages: 1673
Previously, we reported a mechanosensitive ion channel, TRPV4, along with functional connexin hemichannels on the basolateral surface of the ocular nonpigmented ciliary epithelium (NPE). In the lens, TRPV4-mediated hemichannel opening is part of a fe