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pro vyhledávání: '"Nicholas D. Stafford"'
Autor:
Lorcan O’Toole, Nicholas D. Stafford
Publikováno v:
Treatment of Cancer ISBN: 9780429026638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67e5ab31090aa62970ed2edb2da4aceb
https://doi.org/10.1201/9780429026638-3
https://doi.org/10.1201/9780429026638-3
Publikováno v:
Head & Neck. 38:E1903-E1908
Background The neutrophil/lymphocyte ratio (NLR) has been found to be predictive of survival outcome in a range of tumors. The purpose of this study was to investigate the prognostic value of pretreatment (NLR) in patients with laryngeal squamous cel
Autor:
Nicholas D. Stafford, Andrew W Beavis, John Greenman, Rishi Srivastava, Ramsah Cheah, Victoria L. Green
Publikováno v:
International journal of oncology. 51(4)
Radiotherapy is the standard treatment for head and neck squamous cell carcinoma (HNSCC), however, radioresistance remains a major clinical problem despite significant improvements in treatment protocols. Therapeutic outcome could potentially be impr
Publikováno v:
Head & Neck. 37:449-459
Background The tumour microenvironment is a highly complex region where multiple interactions occur between host and cancer cells. The host response is defined by the presence and function of different tumour infiltrating lymphocytes and cytokines. H
Autor:
Elena Kuvshinova, Laszlo Karsai, Nicholas D. Stafford, Stephen Crank, Ruth Bower, Dmitriy Kuvshinov, Victoria L. Green, John Greenman
Publikováno v:
Future Science OA
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/re
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 265:63-67
Conventional chemotherapy has no role to play in the curative treatment of laryngeal carcinoma, yet the mortality rate from advanced disease has improved little over the last 20 years. Somatostatin is a naturally occurring peptide, which exerts anti-
Autor:
Nicholas D. Stafford, J. Greenman, James N. E. Ashman, Lynn Cawkwell, Helen K. Berrieman, Alastair MacDonald, Harriet S. Patmore
Publikováno v:
Cancer Letters. 258:55-62
Head and neck squamous cell carcinoma (HNSCC) demonstrates significant differences in the biological and clinical behaviour of tumours found at different sub-sites. We investigated the genetic profiles of 68 carcinomas (larynx n=35, hypopharynx n=19,
Publikováno v:
Headneck. 38
The neutrophil/lymphocyte ratio (NLR) has been found to be predictive of survival outcome in a range of tumors. The purpose of this study was to investigate the prognostic value of pretreatment (NLR) in patients with laryngeal squamous cell carcinoma
Publikováno v:
Clinical Otolaryngology. 30:164-168
Objectives: Radiotherapy is one of the principal treatment modalities for many types of head and neck tumour; what effects the dendritic cell (DC) population may have on treatment outcome have not been critically evaluated in laryngeal cancer. Design
Publikováno v:
Clinical Otolaryngology and Allied Sciences. 29:705-708
Survival rates for head and neck cancer are comparatively poor, typically 40% at 5 years. Radiotherapy is one of the most common modalities used to cure early-stage cancers. It has the advantage in that it preserves anatomical structure and function.