Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicholas D. Measom"'
Publikováno v:
Angewandte Chemie (International ed. in English). 60(47)
"Escaping from flatland", by increasing the saturation level and three-dimensionality of drug-like compounds, can enhance their potency, selectivity and pharmacokinetic profile. One approach that has attracted considerable recent attention is the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5102f3b19bb7a9c9e12a81f3db19a416
https://pubmed.ncbi.nlm.nih.gov/34151501
https://pubmed.ncbi.nlm.nih.gov/34151501
Publikováno v:
Comptes Rendus Chimie. 20:601-608
Deprotonation of a chiral alpha-oxygenated nitrile with the base 2,2,6,6-tetramethylpiperidylmagnesium chloride, TMPMgCl, gives rise to a chiral magnesiated nitrile, and this anion has sufficient configurational stability at low temperature to allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e2a1f98fcccd60362e57a7efb13555
https://doi.org/10.1016/j.crci.2016.11.006
https://doi.org/10.1016/j.crci.2016.11.006