Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicholas D. Maynard"'
Autor:
John M. Findlay, Francesc Castro-Giner, Seiko Makino, Emily Rayner, Christiana Kartsonaki, William Cross, Michal Kovac, Danny Ulahannan, Claire Palles, Richard S. Gillies, Thomas P. MacGregor, David Church, Nicholas D. Maynard, Francesca Buffa, Jean-Baptiste Cazier, Trevor A. Graham, Lai-Mun Wang, Ricky A. Sharma, Mark Middleton, Ian Tomlinson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Oesophageal adenocarcinoma is often treated with chemotherapy before surgery. Here, the authors sequence cancer samples before and after chemotherapy and examine how the genome changes, focusing on changes in driver gene mutations and differential cl
Externí odkaz:
https://doaj.org/article/1aea2f25e1f04ce696257305762bffaf
Publikováno v:
Surgical Endoscopy. 36:5319-5325
Background Chyle leaks following oesophagectomy are a frustrating complication of surgery with considerable morbidity. The use of near infra-red (NIR) fluorescence in surgery is an emerging technology and the use of fluorescence to identify the thora
Autor:
Nicholas D. Maynard, Mohan Singh, Prem Chana, Khalid Akbari, Sotiris Mastoridis, Samar Shalaby, Bruno Sgromo
Publikováno v:
Minimally Invasive Therapy & Allied Technologies. 31:380-388
Oesophageal perforations and post-oesophagectomy anastomotic leaks are associated with high morbidity and mortality. Endoscopic vacuum therapy (EVT) is a novel treatment strategy with the potential to promote healing and ameliorate sepsis. Only two c
Autor:
R Marshall, Nicholas D. Maynard, Michela Neccia, Bruno Sgromo, Sotiris Mastoridis, Christine-Bianca Hanganu, Richard S. Gillies, Antonio Giuliani, Giada Bracalente
Publikováno v:
BMC Surgery
BMC Surgery, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Surgery, Vol 21, Iss 1, Pp 1-7 (2021)
Background Jejunal feeding is an invaluable method by which to improve the nutritional status of patients undergoing neoadjuvant and surgical treatment of oesophageal malignancies. However, the insertion of a feeding jejunostomy can cause significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd12dd7ce3f6c968ecfa818ce67de61d
Autor:
Nicholas D. Maynard, Tom Crosby, Nigel Trudgill, Robert J. Walker, Timothy J. Underwood, David A Cromwell, Saqib Rahman
Publikováno v:
Diseases of the Esophagus. 34
For patients with esophageal cancer, producing accurate prediction models for long-term survival after esophagectomy has proved challenging. We investigated whether Random Survival Forests (RSF), a machine learning method, could produce an accurate p
Autor:
Nicholas D. Maynard, Cristina Fiorani, Mark R. Middleton, Richard S. Gillies, Edward A. Dickson, John M. Findlay, Kevin M. Bradley, Somnath Mukherjee
Publikováno v:
European Radiology
Objectives We recently described metabolic nodal stage (mN) and response (mNR) of cancer of the esophagus and gastro-esophageal junction (GEJ) to neoadjuvant chemotherapy (NAC) using 18F-FDG PET-CT as new markers of disease progression, recurrence, a
Publikováno v:
Journal of the Nuffield Department of Surgical Sciences. 2
Gastro-oesophageal reflux disease (GORD) is a common condition in developed countries with an increasing incidence in the UK, currently estimated at 5 per 1000 person-years. Risk factors for GORD include Helicobacter pylori infection, obesity, alcoho
Publikováno v:
Annals of Medicine and Surgery
Aim It is recommended that management of complex benign upper gastrointestinal pathology is discussed at multi disciplinary team (MDT) meetings. American College of Gastroenterology (ACG) guidelines further recommend that treatment delivery is provid
Autor:
Stefan Antonowicz, John M. Findlay, Mark R. Middleton, Ashvina Segaran, Alexa Zhang, Richard S. Gillies, Jihene el Kafsi, Nicholas D. Maynard, Kevin M. Bradley
Publikováno v:
European Radiology
Objectives Fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET-CT) is typically considered to have minimal yield in gastric cancer, and so is not consistently recommended by international guidelines. However, its yield is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11721acf793b685cce62a5f2659412d1
https://orca.cardiff.ac.uk/id/eprint/131984/1/2019_Article_.pdf
https://orca.cardiff.ac.uk/id/eprint/131984/1/2019_Article_.pdf
Autor:
Fergus V. Gleeson, Kevin M. Bradley, Eugene J. Teoh, Mark R. Middleton, Richard S. Gillies, Sara di Carlo, John M. Findlay, James M. Franklin, Nicholas D. Maynard, G E Jones
Publikováno v:
European Radiology. 26:3519-3533
It is unknown whether restaging oesophageal cancer after neoadjuvant therapy with positron emission tomography-computed tomography (PET-CT) is more sensitive than contrast-enhanced CT for disease progression. We aimed to determine this and stratify r