Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicholas D Cober"'
Autor:
Rafael Soares Godoy, Nicholas D Cober, David P Cook, Emma McCourt, Yupu Deng, Liyuan Wang, Kenny Schlosser, Katelynn Rowe, Duncan J Stewart
Publikováno v:
eLife, Vol 12 (2023)
We sought to define the mechanism underlying lung microvascular regeneration in a model of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation. Intratracheal instillation of DT in transgenic mice expressing human diphth
Externí odkaz:
https://doaj.org/article/6be9dda738014335b2a97fbb476221b2
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Background We have previously reported important strain differences in response to SU5416 (SU, a vascular endothelial growth factor receptor 2 inhibitor) in rats and have identified a specific colony of Sprague‐Dawley rats that are hyperresponsive
Externí odkaz:
https://doaj.org/article/bd6bdc2e89554db99b9fe9ce8e38bd00
Publikováno v:
Hypertension. 79:1580-1590
Pulmonary arterial hypertension (PAH) is a deadly disease, characterized by increased vascular resistance, pulmonary arteriolar loss, and occlusive arterial remodeling, leading to eventual right heart failure. Evidence increasingly points to the pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003fc02036c5c7d588fe110502be98e2
https://doi.org/10.1161/hypertensionaha.122.18261
https://doi.org/10.1161/hypertensionaha.122.18261
Autor:
Nicholas D. Cober, Katelynn Rowe, Yupu Deng, Ainara Benavente-Babace, David W. Courtman, Michel Godin, Duncan J. Stewart
Publikováno v:
Journal of Extracellular Biology. 2
Extracellular vesicles (EVs) secreted by stem and progenitor cells have significant potential as cell-free ‘cellular’ therapeutics. Yet, small EVs (in vitro, but less efficiently than the uptake of free EVs. Following intrajugular administration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2fd6772fd1b91561f77c0d3ba8c18f
https://doi.org/10.1002/jex2.94
https://doi.org/10.1002/jex2.94
Autor:
Nicholas D Cober, Rafael Soares Godoy, David P Cook, Emma McCourt, Yupu Deng, Liyuan Wang, Kenny Schlosser, Katelynn Rowe, Duncan J Stewart
Publikováno v:
eLife. 12
We sought to define the mechanism underlying lung microvascular regeneration in a model of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation. Intratracheal instillation of DT in transgenic mice expressing human diphth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5278e7f9ad7b5122549e09487ca203
https://doi.org/10.7554/elife.80900
https://doi.org/10.7554/elife.80900
Autor:
Nicholas D Cober, Rafael Soares Godoy, David P Cook, Emma McCourt, Yupu Deng, Liyuan Wang, Kenny Schlosser, Katelynn Rowe, Duncan J Stewart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920f957e0eee7c6615310d156d6af624
https://doi.org/10.7554/elife.80900.sa2
https://doi.org/10.7554/elife.80900.sa2
Autor:
Nicholas D. Cober, Ketul R. Chaudhary, Yupu Deng, Chyan-Jang Lee, Katelynn Rowe, David W. Courtman, Duncan J. Stewart
BackgroundPulmonary arterial hypertension (PAH) is triggered by pulmonary vascular endothelial cell apoptosis and microvascular loss; therefore, therapies that can regenerate lost vasculature may offer therapeutic benefit. Endothelial colony forming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b5765226a18ca65be76f5cad83f36a
https://doi.org/10.1101/2022.11.05.514522
https://doi.org/10.1101/2022.11.05.514522
Autor:
Nicholas D Cober, Yupu Deng, Katelynn Rowe, Ainara Benavente-Babace, David W Courtman, Michel Godin, Duncan J Stewart
Publikováno v:
Circulation. 144
Introduction: Pulmonary arterial hypertension (PAH) is a devastating lung disease with no curative treatments available. Cell-based therapies are a promising regenerative approach, including the direct application of stem cell derived extracellular v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2c1ac283b91b0fe0ede9fdf3e07dcd2
https://doi.org/10.1161/circ.144.suppl_1.12242
https://doi.org/10.1161/circ.144.suppl_1.12242
Publikováno v:
Eur Respir J
Pulmonary arterial hypertension (PAH) is a devastating disease that involves pulmonary vasoconstriction, small vessel obliteration, large vessel thickening and obstruction, and development of plexiform lesions. PAH vasculopathy leads to progressive i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbe22629808925e2b53ed9066a9ea50
https://europepmc.org/articles/PMC8316496/
https://europepmc.org/articles/PMC8316496/
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We have previously reported important strain differences in response to SU5416 (SU, a vascular endothelial growth factor receptor 2 inhibitor) in rats and have identified a specific colony of Sprague‐Dawley rats that are hyperresponsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d945eaff0bf894871976a7c8b9ae4f
https://doi.org/10.1161/jaha.120.019488
https://doi.org/10.1161/jaha.120.019488