Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Nicholas C. Popescu"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 4, Pp 412-419 (2004)
The identification of genes undergoing genetic or epigenetic alterations and contributing to the development of cancer is critical to our understanding of the molecular mechanisms of carcinogenesis. A new approach in identifying alterations of genes
Externí odkaz:
https://doaj.org/article/e1e936402818499d9838103200043407
Autor:
Drazen B. Zimonjic, Marian E. Durkin, Catherine L. Keck-Waggoner, Sang-Won Park, Snorri S. Thorgeirsson, Nicholas C. Popescu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 5, Pp 390-396 (2003)
Signaling by the transforming growth factor (TGF)family members is transduced from the cell surface to the nucleus by the Smad group of intracellular proteins. Because we detected alterations on the long arm of chromosome 5, we examined the status of
Externí odkaz:
https://doaj.org/article/10afa73f6cf54fb08e27a12f0c301a01
Supplementary Methods and Materials and Figure Legends for Figures 1-2 from DLC1 Interaction with S100A10 Mediates Inhibition of In Vitro Cell Invasion and Tumorigenicity of Lung Cancer Cells through a RhoGAP-Independent Mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bfe7a9bbf5789a970be7decb6cdeb5
https://doi.org/10.1158/0008-5472.22388481
https://doi.org/10.1158/0008-5472.22388481
Autor:
Yves Pommier, John N. Weinstein, David J. Goldstein, Mirit I. Aladjem, Nicholas C. Popescu, Ernest S. Kawasaki, Yong-Wei Zhang, Ling-Hua Meng, Hong-Liang Zhang, Tsutomu Shimura, Hong Liu, Zhi-Yong Liao, Philip L. Lorenzi, Drazen B. Zimonjic, Yong-Hong Wang, Uma Shankavaram, Audrey Player, Ze-Hong Miao
Supplementary Table 1 from Nonclassic Functions of Human Topoisomerase I: Genome-Wide and Pharmacologic Analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6e0ca06d590085bac545a2d742f10b
https://doi.org/10.1158/0008-5472.22367432.v1
https://doi.org/10.1158/0008-5472.22367432.v1
Supplementary Figure 1 from DLC1 Interaction with S100A10 Mediates Inhibition of In Vitro Cell Invasion and Tumorigenicity of Lung Cancer Cells through a RhoGAP-Independent Mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e26ee6b1f318aba0515b5c0406a39d9
https://doi.org/10.1158/0008-5472.22388487
https://doi.org/10.1158/0008-5472.22388487
Autor:
Douglas R. Lowy, Nicholas C. Popescu, William C. Vass, Xu-Yu Yang, Lyra Olson, Brajendra K. Tripathi, Dunrui Wang, Marian E. Durkin, Xiaolan Qian
PDF file - 304K, Suppl. Table 1: Validated siRNAs used in the current studies Suppl. Fig. 1 Stress fiber formation in MEFs with or without v-Ras expression. Suppl. Fig. 2 The spontaneous transformation is reproducible using another Adeno-Cre treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcde8a1fba00e16c4831ea7f45eb4d81
https://doi.org/10.1158/0008-5472.22394400
https://doi.org/10.1158/0008-5472.22394400
Autor:
Yves Pommier, John N. Weinstein, David J. Goldstein, Mirit I. Aladjem, Nicholas C. Popescu, Ernest S. Kawasaki, Yong-Wei Zhang, Ling-Hua Meng, Hong-Liang Zhang, Tsutomu Shimura, Hong Liu, Zhi-Yong Liao, Philip L. Lorenzi, Drazen B. Zimonjic, Yong-Hong Wang, Uma Shankavaram, Audrey Player, Ze-Hong Miao
The biological functions of nuclear topoisomerase I (Top1) have been difficult to study because knocking out TOP1 is lethal in metazoans. To reveal the functions of human Top1, we have generated stable Top1 small interfering RNA (siRNA) cell lines fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b425eb017b0ddd20376097ab2a2bc4
https://doi.org/10.1158/0008-5472.c.6495548
https://doi.org/10.1158/0008-5472.c.6495548
Autor:
Robert A. Weinberg, Harvey F. Lodish, Elinor Ng Eaton, Wenjun Guo, Nicholas C. Popescu, Ferenc Reinhardt, Ann Gifford, Megan Kaba, Sendurai A. Mani, Drazen B. Zimonjic, Beiyan Zhou, Cheng Cheng Zhang, Mai-Jing Liao
Supplementary Figures 1-2 from Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have In vivo Repopulating Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954fae57b80d6b0f1c93d6a8c13a192a
https://doi.org/10.1158/0008-5472.22367466
https://doi.org/10.1158/0008-5472.22367466
Autor:
Douglas R. Lowy, Nicholas C. Popescu, William C. Vass, Xu-Yu Yang, Lyra Olson, Brajendra K. Tripathi, Dunrui Wang, Marian E. Durkin, Xiaolan Qian
The tumor suppressor gene deleted in liver cancer-1 (DLC1), which encodes a protein with strong RhoGAP (GTPase activating protein) activity and weak Cdc42GAP activity, is inactivated in various human malignancies. Following Dlc1 inactivation, mouse e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d160bdb8d0db77be661194b8ded83740
https://doi.org/10.1158/0008-5472.c.6504021.v1
https://doi.org/10.1158/0008-5472.c.6504021.v1
Autor:
Robert A. Weinberg, Harvey F. Lodish, Elinor Ng Eaton, Wenjun Guo, Nicholas C. Popescu, Ferenc Reinhardt, Ann Gifford, Megan Kaba, Sendurai A. Mani, Drazen B. Zimonjic, Beiyan Zhou, Cheng Cheng Zhang, Mai-Jing Liao
The identification of mammary gland stem cells (MGSC) or progenitors is important for the study of normal breast development and tumorigenesis. Based on their immunophenotype, we have isolated a population of mouse mammary gland cells that are capabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159b863e6053b5e18e5388b593977f9d
https://doi.org/10.1158/0008-5472.c.6495558
https://doi.org/10.1158/0008-5472.c.6495558