Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicholas C. Love"'
Autor:
Jinghua Lu, François Van Laethem, Abhisek Bhattacharya, Marco Craveiro, Ingrid Saba, Jonathan Chu, Nicholas C. Love, Anastasia Tikhonova, Sergei Radaev, Xiaoping Sun, Annette Ko, Tomer Arnon, Eric Shifrut, Nir Friedman, Nan-Ping Weng, Alfred Singer, Peter D. Sun
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
For T cells, functional antigen receptors are selected in the thymus from a pre-selection repertoire by interaction with self MHCs. Here the authors show that specific, non-germline coded features located in the complementarity determining region 3 o
Externí odkaz:
https://doaj.org/article/2135b8948a994dbda344f75d21b684fb
Publikováno v:
Respiratory Medicine and Research. 83:100985
Autor:
Tomer Arnon, Marco Craveiro, Nicholas C. Love, Sergei Radaev, Nan-ping Weng, Abhisek Bhattacharya, Xiaoping Sun, Jonathan Chu, Jinghua Lu, Nir Friedman, Ingrid Saba, Eric Shifrut, Anastasia N. Tikhonova, Alfred Singer, Annette Ko, Peter D. Sun, François Van Laethem
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
The αβ T cell receptor (TCR) repertoire on mature T cells is selected in the thymus, but the basis for thymic selection of MHC-restricted TCRs from a randomly generated pre-selection repertoire is not known. Here we perform comparative repertoire s