Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Nicholas C. Jacobs"'
Autor:
Michael V. Heinz, Damien Lekkas, Veronica Abreu, Camilla Lee, Lisa A. Marsch, Nicholas C. Jacobson
Publikováno v:
npj Mental Health Research, Vol 3, Iss 1, Pp 1-14 (2024)
Abstract Depression and anxiety frequently co-occur with opioid use disorder (OUD) yet are often overlooked in standard OUD treatments. This study evaluated the feasibility, acceptability, and preliminary effectiveness of a mobile application designe
Externí odkaz:
https://doaj.org/article/2ad98788ca1c48c39cfc6b2054eb45a6
Publikováno v:
Digital Biomarkers, Vol 8, Iss 1, Pp 181-193 (2024)
Introduction: Existing theories and empirical works link phone use with anxiety; however, most leverage subjective self-reports of phone use (e.g., validated questionnaires) that may not correspond well with true behavior. Moreover, most works linkin
Externí odkaz:
https://doaj.org/article/d53585d99d134088a5efc0343e818989
Autor:
Damien Lekkas, Nicholas C. Jacobson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Suicidal thought and behavior (STB) is highly stigmatized and taboo. Prone to censorship, yet pervasive online, STB risk detection may be improved through development of uniquely insightful digital markers. Focusing on Sanctioned Suicide, an
Externí odkaz:
https://doaj.org/article/8eab5ef2522a4d5c8da3c72cd042693c
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Major Depressive Disorder (MDD) presents considerable challenges to diagnosis and management due to symptom variability across time. Only recent work has highlighted the clinical implications for interrogating depression symptom variability.
Externí odkaz:
https://doaj.org/article/10a184fc9fc448fa8edbcce60ca5daf0
Autor:
Anastasiia Pendergrass, Thijn R. Brummelkamp, India C Bradley, Jiwoong Park, Niki Song, Nicholas L Bean, Jinmei Li, Sandeep Kumar, Nicholas C Jacobs, Ariella Coler-Reilly, Roland E. Dolle, Damon T. Burrow, Malini Varadarajan, Timothy R. Peterson, Tanya H Pierre, Jan E. Carette, Sydney K Hart
Chloroquine is an anti-malarial and immunosuppressant drug that has cationic amphipathic chemical properties. We performed genome-wide screens in human cells with chloroquine and several other widely used cationic amphipathic drugs (CADs) including t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072420f8c7d34ecdaba1d0254430ac42
https://doi.org/10.1101/2020.04.10.035683
https://doi.org/10.1101/2020.04.10.035683
Moore’s law states that computers get faster and less expensive over time. In contrast in biopharma, there is the reverse spelling, Eroom’s law, which states that drug discovery is getting slower and costing more money every year. Herein, we prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463e6f4f65459ba03b0f2fcba29e61cb
https://doi.org/10.1101/487157
https://doi.org/10.1101/487157
Autor:
Gisbert W. Teepe, Yanick X. Lukic, Birgit Kleim, Nicholas C. Jacobson, Fabian Schneider, Prabhakaran Santhanam, Elgar Fleisch, Tobias Kowatsch
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Depression remains a global health problem, with its prevalence rising worldwide. Digital biomarkers are increasingly investigated to initiate and tailor scalable interventions targeting depression. Due to the steady influx of new
Externí odkaz:
https://doaj.org/article/b38e250ed69b4476a034e82678bc8ca0
Autor:
Nicholas C. Jacobson, Brandon Feng
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Background Generalized anxiety disorder (GAD) is a highly prevalent condition. Monitoring GAD symptoms requires substantial time, effort, and cost. The development of digital phenotypes of GAD may enable new scalable, timely, and inexpensive
Externí odkaz:
https://doaj.org/article/a9a9a17b3f454bcbaed3ca0797f5a351
Autor:
Daniel Zarate, Vasileios Stavropoulos, Michelle Ball, Gabriel de Sena Collier, Nicholas C. Jacobson
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-24 (2022)
Abstract Background This PRISMA systematic literature review examined the use of digital data collection methods (including ecological momentary assessment [EMA], experience sampling method [ESM], digital biomarkers, passive sensing, mobile sensing,
Externí odkaz:
https://doaj.org/article/fe70c44a4516490babe916c70a3a27e7
Autor:
Michael V. Heinz, Sukanya Bhattacharya, Brianna Trudeau, Rachel Quist, Seo Ho Song, Camilla M. Lee, Nicholas C. Jacobson
Publikováno v:
Digital Health, Vol 9 (2023)
Background With a rapidly expanding gap between the need for and availability of mental health care, artificial intelligence (AI) presents a promising, scalable solution to mental health assessment and treatment. Given the novelty and inscrutable nat
Externí odkaz:
https://doaj.org/article/875af9a53e9c4db18d39fc8438d77de1