Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicholas C. Hoffend"'
Autor:
Jason B. Muhitch, Nicholas C. Hoffend, Gissou Azabdaftari, Austin Miller, Wiam Bshara, Carl D. Morrison, Thomas Schwaab, Scott I. Abrams
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Tumor-associated macrophages have been well-characterized in solid malignancies, including renal cell carcinoma and generally correlate with poor prognosis. However, the molecular mechanisms which govern intratumoral macrophage behavior and
Externí odkaz:
https://doaj.org/article/e4701ddebf774665811e8d7e4d12c060
Publikováno v:
Epigenetics, Vol 12, Iss 2, Pp 105-112 (2017)
microRNAs (miRs) are small noncoding RNAs that regulate/fine tune many cellular protein networks by targeting mRNAs for either degradation or translational inhibition. Dicer, a type III endoribonuclease, is a critical component in miR biogenesis and
Externí odkaz:
https://doaj.org/article/321f66ba8ab545b090cc8d8f244de2bd
Autor:
Jason B. Muhitch, Thomas Schwaab, Scott I. Abrams, Junko Matsuzaki, Kunle Odunsi, Wiam Bshara, Graham W. Warren, Lalith K. Kumaraswamy, Leighton C. Stein, Nicholas C. Hoffend, Austin Miller, Lilia Heit, Vincent Goritz, Mohammad Habiby Kermany, Timothy B. Winslow, Anurag K. Singh
Purpose: While stereotactic body radiotherapy (SBRT) can reduce tumor volumes in patients with metastatic renal cell carcinoma (mRCC), little is known regarding the immunomodulatory effects of high-dose radiation in the tumor microenvironment. The ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48da3407f3dc47421d384bf0509b61d
https://doi.org/10.1158/1078-0432.c.6526448
https://doi.org/10.1158/1078-0432.c.6526448
Autor:
Jason B. Muhitch, Thomas Schwaab, Scott I. Abrams, Junko Matsuzaki, Kunle Odunsi, Wiam Bshara, Graham W. Warren, Lalith K. Kumaraswamy, Leighton C. Stein, Nicholas C. Hoffend, Austin Miller, Lilia Heit, Vincent Goritz, Mohammad Habiby Kermany, Timothy B. Winslow, Anurag K. Singh
Supplementary figure S3 shows gating strategy and isotype staining of live tumor cells used for patient samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f35a07ca3caf75c3a14776afa288e9
https://doi.org/10.1158/1078-0432.22466849
https://doi.org/10.1158/1078-0432.22466849
Autor:
Jason B. Muhitch, Thomas Schwaab, Scott I. Abrams, Junko Matsuzaki, Kunle Odunsi, Wiam Bshara, Graham W. Warren, Lalith K. Kumaraswamy, Leighton C. Stein, Nicholas C. Hoffend, Austin Miller, Lilia Heit, Vincent Goritz, Mohammad Habiby Kermany, Timothy B. Winslow, Anurag K. Singh
Supplementary table 3 shows immunohistochemical antibodies and dilutions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7d7f074c2a6a47cb6b8d1cd256a9e6
https://doi.org/10.1158/1078-0432.22466834
https://doi.org/10.1158/1078-0432.22466834
Autor:
Nicholas C. Hoffend, Thomas Schwaab, Jason B. Muhitch, Scott I. Abrams, Anurag K. Singh, Jacky Chow
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Strong evidence supports the tumor immune landscape as a determinant of patient responses to immunotherapy. Readily available therapies, including radiation, are being investigated as modifying agents with immune checkpoint blockade. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f83e7e04ec01ba8f5eea4a117a06e0e
https://doi.org/10.1073/pnas.2001933117
https://doi.org/10.1073/pnas.2001933117
Publikováno v:
Epigenetics. 12:105-112
microRNAs (miRs) are small noncoding RNAs that regulate/fine tune many cellular protein networks by targeting mRNAs for either degradation or translational inhibition. Dicer, a type III endoribonuclease, is a critical component in miR biogenesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afcf26d0fcdff9684b372fd094f2d1b
https://doi.org/10.1080/15592294.2016.1267886
https://doi.org/10.1080/15592294.2016.1267886
Autor:
Wiam Bshara, Gissou Azabdaftari, Austin Miller, Nicholas C. Hoffend, Carl Morrison, Jason B. Muhitch, Thomas Schwaab, Scott I. Abrams
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Tumor-associated macrophages have been well-characterized in solid malignancies, including renal cell carcinoma and generally correlate with poor prognosis. However, the molecular mechanisms which govern intratumoral macrophage behavior and patient o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5d75336ceefde82f8001934c2c8b6d
https://doi.org/10.1186/s40425-019-0630-0
https://doi.org/10.1186/s40425-019-0630-0
Autor:
Nicholas C. Hoffend, Jacky Chow, Anurag K. Singh, Scott I. Abrams, Madeline Gaudieri, Jason B. Muhitch, Thomas Schwaab
Publikováno v:
Clinical Cancer Research. 27:PO-038
Robust preclinical investigations into radiation-induced immunogenicity has led to increased enthusiasm for combining radiation with immunotherapy. Promising results in a limited number of patients treated with radiotherapy and immune-activating stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789e95e68731ec424222457d70b87f03
https://doi.org/10.1158/1557-3265.radsci21-po-038
https://doi.org/10.1158/1557-3265.radsci21-po-038
Publikováno v:
Oncotarget
// Nicholas C. Hoffend 1 , William J. Magner 1, 3 , Thomas B. Tomasi 1, 2, 3 1 Laboratory of Molecular Medicine, Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York, USA 2 Department of Medicine, State University of New York, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564a6f29c9df2973fb8ad234a3ffed0c
https://doi.org/10.18632/oncotarget.10273
https://doi.org/10.18632/oncotarget.10273