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pro vyhledávání: '"Nicholas C Keith"'
Autor:
Nicole Hajicek, Nicholas C Keith, Edhriz Siraliev-Perez, Brenda RS Temple, Weigang Huang, Qisheng Zhang, T Kendall Harden, John Sondek
Publikováno v:
eLife, Vol 8 (2019)
Direct activation of the human phospholipase C-γ isozymes (PLC-γ1, -γ2) by tyrosine phosphorylation is fundamental to the control of diverse biological processes, including chemotaxis, platelet aggregation, and adaptive immunity. In turn, aberrant
Externí odkaz:
https://doaj.org/article/1d56ad94b75749b5a9664ffba654d969
Autor:
Rachael E. Workman, Marie J. Stoltzfus, Nicholas C. Keith, Chad W. Euler, Joseph Bondy-Denomy, Joshua W. Modell
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113849- (2024)
Summary: CRISPR-Cas immune systems provide bacteria with adaptive immunity against bacteriophages, but they are often transcriptionally repressed to mitigate auto-immunity. In some cases, CRISPR-Cas expression increases in response to a phage infecti
Externí odkaz:
https://doaj.org/article/8f1d1d1e943a4010b6fec27b0be2675a