Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nicholas C Jacobs"'
Autor:
Amanda C Collins, Sukanya Bhattacharya, Jenny Y Oh, Abigail Salzhauer, Charles T Taylor, Kate Wolitzky-Taylor, Robin L Aupperle, Alan J Budney, Nicholas C Jacobson
Publikováno v:
JMIR Formative Research, Vol 8, p e54751 (2024)
BackgroundExisting interventions for co-occurring depression and cannabis use often do not treat both disorders simultaneously and can result in higher rates of symptom relapse. Traditional in-person interventions are often difficult to obtain due to
Externí odkaz:
https://doaj.org/article/588d97a6b8594471b9d21d3edf166d84
Autor:
Anastasiia Pendergrass, Thijn R. Brummelkamp, India C Bradley, Jiwoong Park, Niki Song, Nicholas L Bean, Jinmei Li, Sandeep Kumar, Nicholas C Jacobs, Ariella Coler-Reilly, Roland E. Dolle, Damon T. Burrow, Malini Varadarajan, Timothy R. Peterson, Tanya H Pierre, Jan E. Carette, Sydney K Hart
Chloroquine is an anti-malarial and immunosuppressant drug that has cationic amphipathic chemical properties. We performed genome-wide screens in human cells with chloroquine and several other widely used cationic amphipathic drugs (CADs) including t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072420f8c7d34ecdaba1d0254430ac42
https://doi.org/10.1101/2020.04.10.035683
https://doi.org/10.1101/2020.04.10.035683
Moore’s law states that computers get faster and less expensive over time. In contrast in biopharma, there is the reverse spelling, Eroom’s law, which states that drug discovery is getting slower and costing more money every year. Herein, we prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463e6f4f65459ba03b0f2fcba29e61cb
https://doi.org/10.1101/487157
https://doi.org/10.1101/487157
Autor:
Damien Lekkas, Nicholas C Jacobson
Publikováno v:
Digital Health, Vol 9 (2023)
Background The socially unattractive and stigmatizing nature of suicidal thought and behavior (STB) makes it especially susceptible to censorship across most modern digital communication platforms. The ubiquitous integration of technology with day-to
Externí odkaz:
https://doaj.org/article/3dfbe2342bba4db89002bf1be35c6a7a
Autor:
Cynthia I Campbell, Ching-Hua Chen, Sara R Adams, Asma Asyyed, Ninad R Athale, Monique B Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C Jacobson, Heather K Jones, David Kotz, Chantal A Lambert-Harris, Zhiguo Li, Bethany McLeman, Varun Mishra, Catherine Stanger, Geetha Subramaniam, Weiyi Wu, Christopher Zegers, Lisa A Marsch
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e45556 (2023)
BackgroundMultiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individua
Externí odkaz:
https://doaj.org/article/1a9b68ddfd974a19b502e2f5ff319c20
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e40308 (2023)
BackgroundThe impacts of the COVID-19 pandemic on mental health worldwide and in the United States have been well documented. However, there is limited research examining the long-term effects of the pandemic on mental health, particularly in relatio
Externí odkaz:
https://doaj.org/article/2748a692d5684ca5a1c75eaf9adb1d67
Autor:
Song Li, Uwe Ohler, Aleksandra Mihailovic, Pavol Cekan, Claudia Bognanni, Thomas Tuschl, Carl S. Leonhardt, Thalia A. Farazi, Erik Larsson, Klaas E.A. Max, Nicholas C. Jacobs, Neelanjan Mukherjee, Stefanie Gerstberger, Masashi Yamaji, Cindy Meyer
Recent studies implicated the RNA-binding protein with multiple splicing (RBPMS) family of proteins in oocyte, retinal ganglion cell, heart, and gastrointestinal smooth muscle development. These RNA-binding proteins contain a single RNA recognition m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7f308990675ed8ed9ba6d84e4aa94f
https://europepmc.org/articles/PMC4114688/
https://europepmc.org/articles/PMC4114688/
Publikováno v:
JMIR Formative Research, Vol 6, Iss 12, p e40139 (2022)
BackgroundCannabis misuse in young adults is a major public health concern. An important predictor of continued use is cannabis craving. Due to the time-varying nature of cravings, brief momentary interventions delivered while cravings are elevated m
Externí odkaz:
https://doaj.org/article/300bfa4a3892419cada85055c6d489ed
Publikováno v:
PLOS Digital Health, Vol 1, Iss 11, p e0000126 (2022)
The current manuscript is a commentary on "Mobile phone-based interventions for mental health: A systematic meta-review of 14 meta-analyses of randomized controlled trials". Although embedded within a nuanced discussion, one of the primary conclusion
Externí odkaz:
https://doaj.org/article/195aac7b7df141539c6e21e028a4c254
Autor:
Uwe Ohler, Nicholas C. Jacobs, Markus Hafner, Perry J. Blackshear, Neelanjan Mukherjee, Elizabeth A. Kennington, Jeffrey Nusbaum, Thomas Tuschl
Publikováno v:
Genome Biology
Background ZFP36, also known as tristetraprolin or TTP, and ELAVL1, also known as HuR, are two disease-relevant RNA-binding proteins (RBPs) that both interact with AU-rich sequences but have antagonistic roles. While ELAVL1 binding has been profiled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cea5d16ca02b7f19e015b615cb3b01
https://pubmed.ncbi.nlm.nih.gov/24401661
https://pubmed.ncbi.nlm.nih.gov/24401661