Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicholas Bland"'
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Converging evidence suggests that transcranial alternating current stimulation (tACS) may entrain endogenous neural oscillations to match the frequency and phase of the exogenously applied current and this entrainment may outlast the stimulation (alt
Externí odkaz:
https://doaj.org/article/13937d2739594c4ab26e3658bc786dd2
Autor:
Andrew Novak, David Laughton, Rebecca Lane, Emma Blackham, Jennifer Thomas, Elli Chatzopoulou, Joseph Wrigglesworth, Abdul Quddus, Saleh Ahmed, David Cousin, Lorna Duffy, Nathalie Dubois, John Unitt, Katalin Orban, Edward Browne, Michelle Ward, David Mycock, Maria Ieva, Nicholas Bland, Pascal George, Timothy Bourne, Hélène Asnagli, Louise Birch, Geraint Jones
Publikováno v:
Journal of Medicinal Chemistry. 65:16640-16650
Herein, we report the discovery of a first-in-class chemotype 2-(alkylsulfonamido)thiazol-4-yl)acetamides that act as pan-selective inhibitors of cytidine 5'-triphosphate synthetase (CTPS1/2), critical enzymes in the
Transcranial alternating current stimulation (tACS) has been proposed to modulate neural activity through two primary mechanisms: entrainment and neuroplasticity. The current study aimed to probe both of these mechanisms in the context of the sensori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f39f30de38a328d0a006b8e8d8d21b36
https://doi.org/10.1101/2022.10.17.512611
https://doi.org/10.1101/2022.10.17.512611
Autor:
Ruth Roberts, John S. Fossey, Rosanna Scarll, Timothy Schulz-utermoehl, Rebecca Lane, Alexander Quy, Badarinath Ampolu, Abigail Gulliver, Andrew G. Leach, Angelo Agathanggelou, Geraint Jones, Daniel T. Payne, Louise Male, Nicholas Bland, Jane Theresa Brown, Xingjian Li, Michael J. Morton, Lee Hale, Daniel Hamza, Elena G. Merisor, Mark J. Dutton, Tatjana Stankovic, Catherine A. Fitton, Stevenson Brett W
Publikováno v:
Li, X, Payne, D T, Ampolu, B, Bland, N, Brown, J T, Dutton, M J, Fitton, C A, Gulliver, A, Hale, L, Hamza, D, Jones, G, Lane, R, Leach, A G, Male, L, Merisor, E G, Morton, M J, Quy, A S, Roberts, R, Scarll, R, Schulz-Utermoehl, T, Stankovic, T, Stevenson, B, Fossey, J S & Agathanggelou, A 2019, ' Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia ', MedChemComm, vol. 10, no. 8, pp. 1379-1390 . https://doi.org/10.1039/c9md00297a
A protocol for growing, extracting and derivatising parthenolide obtained from feverfew varieties is reported. Aminated parthenolide derivatives were prepared via 1,4-addition of primary or secondary amines utilising established and modified methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b514a26009762ba3783399a798b94dfa
https://doi.org/10.26434/chemrxiv.7629680.v1
https://doi.org/10.26434/chemrxiv.7629680.v1