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pro vyhledávání: '"Nicholas B. Watson"'
Autor:
Anthony R. Allen, Jia-Fei Poon, Rory C. McAtee, Nicholas B. Watson, Derek A. Pratt, Corey R.J. Stephenson
Publikováno v:
ACS catalysis. 12(14)
Alkene aminoarylation with arylsulfonylacetamides via a visible-light mediated radical Smiles-Truce rearrangement represents a convenient approach to the privileged arylethylamine pharmacaphore traditionally generated by circuitous, multi-step sequen
Publikováno v:
Cancer Letters. 241:13-22
Mutations in DNA are generally considered to have an etiologic role in the development of cancer. If so, it follows that reducing the frequency of such mutations will reduce the incidence of cancer induced by mutagens. Recent advances in elucidating
Publikováno v:
Advances in experimental medicine and biology. 614
Endogenously generated reactive oxygen species and genotoxic carcinogens can covalently modify bases in cellular DNA. If not recognized and removed prior to S-phase of the cell cycle, such modifications can block DNA replication fork progression. If
Publikováno v:
Advances In Experimental Medicine And Biology ISBN: 9780387749105
Endogenously generated reactive oxygen species and genotoxic carcinogens can covalently modify bases in cellular DNA. If not recognized and removed prior to S-phase of the cell cycle, such modifications can block DNA replication fork progression. If
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b0eccd0d7696557410404c7d896a04
https://doi.org/10.1007/978-0-387-74911-2_16
https://doi.org/10.1007/978-0-387-74911-2_16
Autor:
Nicholas B. Watson, Wolfgang Zacharias, Denise R. Clark, W. Glenn McGregor, Suparna Mukhopadhyay
Publikováno v:
Nucleic acids research. 32(19)
The REV1 gene encodes a Y-family DNA polymerase that has been postulated to have both catalytic and structural functions in translesion replication past UV photoproducts in mammalian cells. To examine if REV1 is implicated in DNA damage tolerance mec
Autor:
Marilyn, Diaz, Nicholas B, Watson, Gene, Turkington, Laurent K, Verkoczy, Norman R, Klinman, William Glenn, McGregor
Publikováno v:
Molecular cancer research : MCR. 1(11)
In the budding yeast Saccharomyces cerevisiae, DNA polymerase zeta (pol zeta) is responsible for the great majority of mutations generated during error-prone translesion replication of DNA that contains UV-induced lesions. The catalytic subunit of po